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D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
11702
World Ranking
11485
National Ranking
223

Overview

Pilar Santisteban is affiliated with the Spanish National Research Council in Spain. Their research spans multiple fields within biochemistry, genetics, and molecular biology, with a focus that also intersects medicine. The scientist has contributed significantly to molecular biology, endocrinology, diabetes and metabolism, genetics, cell biology, and cancer research.

The scientist's main research topics incorporate thyroid cancer diagnosis and treatment, RNA research and splicing, Hippo pathway signaling and YAP/TAZ, cancer-related molecular mechanisms, Wnt/β-catenin signaling in development and cancer, RNA regulation and disease, and fibroblast growth factor research.

Their recent publications include the following papers:

  • ADAR1-mediated RNA editing is a novel oncogenic process in thyroid cancer and regulates miR-200 activity (2020, Oncogene)
  • Gene network transitions in embryos depend upon interactions between a pioneer transcription factor and core histones (2020, Nature Genetics)
  • Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer (2024, Nature Communications)
  • BRAF V600E Status Sharply Differentiates Lymph Node Metastasis-associated Mortality Risk in Papillary Thyroid Cancer (2021, The Journal of Clinical Endocrinology & Metabolism)
  • An ADAR1-dependent RNA editing event in the cyclin-dependent kinase CDK13 promotes thyroid cancer hallmarks (2021, Molecular Cancer)

Frequent co-authors include Celia Fernández-Méndez, Garcilaso Riesco-Eizaguirre, Julia Ramírez-Moya, Carlos Carrasco-López, and Antonio De la Vieja.

Pilar Santisteban has published regularly in venues such as Thyroid, Endocrine Abstracts, Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, Endocrine Related Cancer, and Cancers.

Best Publications

  • Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer

    Michael Mingzhao Xing;Ali S. Alzahrani;Kathryn A. Carson;David Viola

  • mRNA circularization by METTL3–eIF3h enhances translation and promotes oncogenesis

    Junho Choe;Shuibin Lin;Shuibin Lin;Shuibin Lin;Wencai Zhang;Qi Liu;Qi Liu

  • Association Between BRAF V600E Mutation and Recurrence of Papillary Thyroid Cancer

    Mingzhao Xing;Ali S. Alzahrani;Kathryn A. Carson;Young Kee Shong

  • The oncogene BRAFV600E is associated with a high risk of recurrence and less differentiated papillary thyroid carcinoma due to the impairment of Na+/I− targeting to the membrane

    Garcilaso Riesco-Eizaguirre;P. Gutiérrez-Martínez;Miguel Angel García-Cabezas;Manuel Nistal

  • Retinoic acid regulates growth hormone gene expression.

    Gabriela Bedo;Pilar Santisteban;Ana Aranda

  • The BRAFV600E Oncogene Induces Transforming Growth Factor β Secretion Leading to Sodium Iodide Symporter Repression and Increased Malignancy in Thyroid Cancer

    Garcilaso Riesco-Eizaguirre;Irene Rodríguez;Antonio De la Vieja;Eugenia Costamagna

  • Thyroglobulin gene expression is regulated by insulin and insulin-like growth factor I, as well as thyrotropin, in FRTL-5 thyroid cells.

    P Santisteban;L D Kohn;R Di Lauro

  • Thyroid transcription factors in development, differentiation and disease

    Lara P. Fernández;Arístides López-Márquez;Pilar Santisteban

  • A perspective view of sodium iodide symporter research and its clinical implications

    Garcilaso Riesco-Eizaguirre;Pilar Santisteban

  • Differential Clinicopathological Risk and Prognosis of Major Papillary Thyroid Cancer Variants.

    Xiaoguang Shi;Rengyun Liu;Fulvio Basolo;Riccardo Giannini

  • Activation of the GLP-1 Receptor by Liraglutide Increases ACE2 Expression, Reversing Right Ventricle Hypertrophy, and Improving the Production of SP-A and SP-B in the Lungs of Type 1 Diabetes Rats.

    Marina Romaní-Pérez;Verónica Outeiriño-Iglesias;Christian M. Moya;Christian M. Moya;Pilar Santisteban

  • The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.

    Iñigo Landa;Sergio Ruiz-Llorente;Cristina Montero-Conde;Lucía Inglada-Pérez

  • Insulin and insulin-like growth factor I regulate a thyroid-specific nuclear protein that binds to the thyroglobulin promoter.

    P Santisteban;A Acebrón;M Polycarpou-Schwarz;R Di Lauro

  • New insights in thyroid follicular cell biology and its impact in thyroid cancer therapy

    Garcilaso Riesco-Eizaguirre;Pilar Santisteban

  • The Functional Interaction between the Paired Domain Transcription Factor Pax8 and Smad3 Is Involved in Transforming Growth Factor-β Repression of the Sodium/Iodide Symporter Gene

    Eugenia Costamagna;Bibian García;Pilar Santisteban

  • DNA Methylation Signatures Identify Biologically Distinct Thyroid Cancer Subtypes

    Sandra Rodríguez-Rodero;Agustín F. Fernández;Juan Luís Fernández-Morera;Patricia Castro-Santos

  • Role of the Wnt pathway in thyroid cancer

    Ana Sastre-Perona;Pilar Santisteban

  • Thyroid-specific gene expression in the multi-step process of thyroid carcinogenesis.

    Purificación Ros;Dévora L Rossi;Alvaro Acebrón;Pilar Santisteban

  • MicroRNA deep-sequencing reveals master regulators of follicular and papillary thyroid tumors.

    Veronika Mancikova;Esmeralda Castelblanco;Elena Pineiro-Yanez;Javier Perales-Paton

  • AssociationBetween BRAFV600EMutationand MortalityinPatientsWithPapillaryThyroidCancer

    Mingzhao Xing;Ali S. Alzahrani;Kathryn A. Carson;David Viola

Frequent Co-Authors

Leonard D. Kohn
Leonard D. Kohn National Institutes of Health
Alfred King-Yin Lam
Alfred King-Yin Lam Griffith University
Piero Crespo
Piero Crespo Spanish National Research Council
Rossella Elisei
Rossella Elisei University of Pisa
Michele De Luca
Michele De Luca University of Modena and Reggio Emilia
Frank J. Slack
Frank J. Slack Beth Israel Deaconess Medical Center
Richard I. Gregory
Richard I. Gregory Boston Children's Hospital
Gonzalo Gómez-López
Gonzalo Gómez-López Universidade de Vigo
Daniela Corda
Daniela Corda National Academies of Sciences, Engineering, and Medicine
James A. Fagin
James A. Fagin Memorial Sloan Kettering Cancer Center

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