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Biology and Biochemistry

D-Index
59
Citations
18750
World Ranking
12298
National Ranking
5260

Overview

Carlo C. Maley is affiliated with Arizona State University in the United States and has contributed extensively to research in biochemistry, genetics, molecular biology, and medicine. Their work spans numerous subfields including molecular biology, cancer research, genetics, oncology, and pathology and forensic medicine.

The scientist's research topics cover a range of areas such as cancer genomics and diagnostics, single-cell and spatial transcriptomics, evolution and genetic dynamics, cancer cells and metastasis, genetic factors in colorectal cancer, radiomics and machine learning in medical imaging, and mathematical biology tumor growth.

Key recent publications by Carlo C. Maley include:

  • Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma (2022) in Cell
  • Cancer risk across mammals (2021) in Nature
  • Extrachromosomal DNA in the cancerous transformation of Barrett's oesophagus (2023) in Nature
  • Exploiting evolutionary steering to induce collateral drug sensitivity in cancer (2020) in Nature Communications
  • Identifying key questions in the ecology and evolution of cancer (2020) in Evolutionary Applications

Frequent co-authors working alongside Carlo C. Maley include Lorraine King, Jeffrey R. Marks, Luis Cisneros, Athena Aktipis, and Diego Mallo.

The scientist has published regularly in several venues, with the most frequent being bioRxiv (Cold Spring Harbor Laboratory), Cancer Research, Nature Communications, Evolution Medicine and Public Health, and Nature.

Best Publications

  • Clonal evolution in cancer

    Mel Greaves;Carlo C. Maley

  • Cancer as an evolutionary and ecological process.

    Lauren M.F. Merlo;John W. Pepper;Brian J. Reid;Carlo C. Maley

  • Genetic clonal diversity predicts progression to esophageal adenocarcinoma

    Carlo C. Maley;Patricia C. Galipeau;Jennifer C. Finley;V. Jon Wongsurawat

  • Pan-cancer analysis of the extent and consequences of intratumor heterogeneity

    Noemi Andor;Trevor A Graham;Marnix Jansen;Li C Xia

  • The Human Tumor Atlas Network: Charting Tumor Transitions Across Space and Time at Single-Cell Resolution

    Orit Rozenblatt-Rosen;Aviv Regev;Aviv Regev;Aviv Regev;Philipp Oberdoerffer;Tal Nawy

  • Cancer across the tree of life: cooperation and cheating in multicellularity

    C. Athena Aktipis;Amy M. Boddy;Gunther Jansen;Urszula Hibner

  • Is eating behavior manipulated by the gastrointestinal microbiota? Evolutionary pressures and potential mechanisms.

    Joe Alcock;Carlo C. Maley;C. Athena Aktipis

  • Potential Mechanisms for Cancer Resistance in Elephants and Comparative Cellular Response to DNA Damage in Humans

    Lisa M Abegglen;Aleah Fox Caulin;Ashley Chan;Kristy Lee

  • Classifying the evolutionary and ecological features of neoplasms

    Carlo C. Maley;Athena Aktipis;Trevor A. Graham;Andrea Sottoriva

  • Peto's Paradox: evolution's prescription for cancer prevention.

    Aleah F. Caulin;Carlo C. Maley

  • Progress in chemoprevention drug development: the promise of molecular biomarkers for prevention of intraepithelial neoplasia and cancer--a plan to move forward.

    Gary J. Kelloff;Scott M. Lippman;Andrew J. Dannenberg;Caroline C. Sigman

  • NSAIDs Modulate CDKN2A, TP53, and DNA Content Risk for Progression to Esophageal Adenocarcinoma

    Patricia C Galipeau;Xiaohong Li;Patricia L Blount;Patricia L Blount;Carlo C Maley

  • Selectively Advantageous Mutations and Hitchhikers in Neoplasms: p16 Lesions Are Selected in Barrett's Esophagus

    Carlo C. Maley;Patricia C. Galipeau;Xiaohong Li;Carissa A. Sanchez

  • Life history trade-offs in cancer evolution

    C. Athena Aktipis;Amy M. Boddy;Robert A. Gatenby;Joel S. Brown

  • Genomic Instability in Cancer: Teetering on the Limit of Tolerance

    Noemi Andor;Carlo C. Maley;Carlo C. Maley;Hanlee P. Ji

  • The combination of genetic instability and clonal expansion predicts progression to esophageal adenocarcinoma.

    Carlo C. Maley;Patricia C. Galipeau;Xiaohong Li;Carissa A. Sanchez

  • A comprehensive survey of clonal diversity measures in Barrett's esophagus as biomarkers of progression to esophageal adenocarcinoma

    Lauren M.F. Merlo;Najaf A. Shah;Xiaohong Li;Patricia L. Blount;Patricia L. Blount

  • Temporal and spatial evolution of somatic chromosomal alterations: a case-cohort study of Barrett's esophagus.

    Xiaohong Li;Patricia C. Galipeau;Thomas G. Paulson;Carissa A. Sanchez

  • Single-cell genotyping demonstrates complex clonal diversity in acute myeloid leukemia

    Amy L. Paguirigan;Jordan Smith;Soheil Meshinchi;Martin Carroll

  • Extent of Low-Grade Dysplasia Is a Risk Factor for the Development of Esophageal Adenocarcinoma in Barrett's Esophagus

    Amitabh Srivastava;Jason L Hornick;Xiaohong Li;Patricia L Blount;Patricia L Blount

Frequent Co-Authors

Brian J. Reid
Brian J. Reid Fred Hutchinson Cancer Research Center
Jeffrey R. Marks
Jeffrey R. Marks Duke University
Trevor A. Graham
Trevor A. Graham Institute of Cancer Research
Peter S. Rabinovitch
Peter S. Rabinovitch University of Washington
Robert D. Odze
Robert D. Odze Brigham and Women's Hospital
Thomas L. Vaughan
Thomas L. Vaughan University of Washington
Joseph Y. Lo
Joseph Y. Lo Duke University
Maciej A. Mazurowski
Maciej A. Mazurowski Duke University
Robert B. West
Robert B. West Stanford University
Kornelia Polyak
Kornelia Polyak Harvard University

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