World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
91
Citations
26730
World Ranking
11866
National Ranking
6087

Research.com Recognitions

  • 1921 - Member of the National Academy of Sciences

Overview

Thomas L. Vaughan is affiliated with the University of Washington in the United States. Their research primarily falls within the broad field of Medicine, with a focus on several subfields including Surgery, Pulmonary and Respiratory Medicine, Molecular Biology, Gastroenterology, and Cancer Research. The body of work encompasses a significant number of publications, particularly concentrated on esophageal and gastric cancer research and treatment.

Key topics of their research include:

  • Esophageal Cancer Research and Treatment
  • Gastric Cancer Management and Outcomes
  • Helicobacter pylori-related gastroenterology studies
  • Eosinophilic Esophagitis
  • Cancer-related gene regulation
  • Gastroesophageal reflux and treatments
  • Gastrointestinal Tumor Research and Treatment

Among recent publications, several highlight genetic associations and clinical heterogeneity in gastroesophageal conditions. Representative papers include:

  • Multitrait genetic association analysis identifies 50 new risk loci for gastro-oesophageal reflux, seven new loci for Barrett's oesophagus and provides insights into clinical heterogeneity in reflux diagnosis (2021, Gut)
  • GWAS meta-analysis of 16 790 patients with Barrett's oesophagus and oesophageal adenocarcinoma identifies 16 novel genetic risk loci and provides insights into disease aetiology beyond the single marker level (2022, Gut)
  • Sex-Specific Genetic Associations for Barrett's Esophagus and Esophageal Adenocarcinoma (2020, Gastroenterology)
  • Germline variation in the insulin-like growth factor pathway and risk of Barrett's esophagus and esophageal adenocarcinoma (2020, Carcinogenesis)
  • Assessing the genetic relationship between gastro-esophageal reflux disease and risk of COVID-19 infection (2021, Human Molecular Genetics)

Frequent co-authors in Vaughan's publications include Harvey A. Risch, Marilie D. Gammon, David C. Whiteman, Douglas A. Corley, and Wong-Ho Chow. These collaborations reflect a multidisciplinary approach to medical research in related fields.

Thomas L. Vaughan's work has appeared in multiple publication venues, notably:

  • UNC Libraries
  • Human Molecular Genetics
  • Gut
  • Gastroenterology
  • Carcinogenesis

Among recognized distinctions, Vaughan is noted as a Member of the National Academy of Sciences, an honor dating back to 1921.

Best Publications

  • Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms

    Emad M El-Omar;Charles S Rabkin;Marilie D Gammon;Thomas L Vaughan

  • Population attributable risks of esophageal and gastric cancers.

    Lawrence S. Engel;Lawrence S. Engel;Wong Ho Chow;Thomas L. Vaughan;Marilie D. Gammon

  • Tobacco, Alcohol, and Socioeconomic Status and Adenocarcinomas of the Esophagus and Gastric Cardia

    Marilie D. Gammon;Habibul Ahsan;Janet B. Schoenberg;A. Brian West

  • Body mass index and risk of adenocarcinomas of the esophagus and gastric cardia.

    Wong Ho Chow;William J. Blot;Thomas L. Vaughan;Harvey A. Risch

  • Epidemiology and Pathogenesis of Esophageal Cancer

    Rebecca S. Holmes;Rebecca S. Holmes;Thomas L. Vaughan;Thomas L. Vaughan

  • An Inverse Relation between cagA + Strains of Helicobacter pylori Infection and Risk of Esophageal and Gastric Cardia Adenocarcinoma

    Wong Ho Chow;Martin J. Blaser;Martin J. Blaser;William J. Blot;Marilie D. Gammon

  • Obesity, alcohol, and tobacco as risk factors for cancers of the esophagus and gastric cardia: adenocarcinoma versus squamous cell carcinoma.

    Thomas L. Vaughan;Scott Davis;Alan Kristal;David B. Thomas

  • Nutrient Intake and Risk of Subtypes of Esophageal and Gastric Cancer

    Susan T. Mayne;Harvey A. Risch;Robert Dubrow;Wong Ho Chow

  • Use of aspirin and other nonsteroidal anti-inflammatory drugs and risk of esophageal and gastric cancer.

    D C Farrow;T L Vaughan;P D Hansten;J L Stanford

  • Barrett’s oesophagus and oesophageal adenocarcinoma: time for a new synthesis

    Brian J. Reid;Xiaohong Li;Patricia C. Galipeau;Thomas L. Vaughan;Thomas L. Vaughan

  • Occupational exposure assessment in case-control studies: opportunities for improvement

    K Teschke;A F Olshan;J L Daniels;A J De Roos

  • Central adiposity and risk of Barrett's esophagus.

    Zoe R. Edelstein;Zoe R. Edelstein;Diana C. Farrow;Diana C. Farrow;Mary P. Bronner;Sheldon N. Rosen

  • Cigarette Smoking and Adenocarcinomas of the Esophagus and Esophagogastric Junction: A Pooled Analysis From the International BEACON Consortium

    Michael B. Cook;Farin Kamangar;Farin Kamangar;David C. Whiteman;Neal D. Freedman

  • Epidemiology and risk factors for gastroesophageal junction tumors: understanding the rising incidence of this disease.

    Matthew F. Buas;Thomas L. Vaughan;Thomas L. Vaughan

  • Effect of Segment Length on Risk for Neoplastic Progression in Patients with Barrett Esophagus

    Rebecca E. Rudolph;Thomas L. Vaughan;Barry E. Storer;Rodger C. Haggitt

  • Body mass index in relation to oesophageal and oesophagogastric junction adenocarcinomas: a pooled analysis from the International BEACON Consortium

    Cathrine Hoyo;Michael B. Cook;Farin Kamangar;Farin Kamangar;Neal D. Freedman

  • A Functional Polymorphism of Toll-Like Receptor 4 Gene Increases Risk of Gastric Carcinoma and Its Precursors

    Georgina Louise Hold;Charles S. Rabkin;Wong-Ho Chow;Malcolm Gavin Smith

  • Gastroesophageal reflux disease, use of H2 receptor antagonists, and risk of esophageal and gastric cancer.

    Diana C. Farrow;Diana C. Farrow;Thomas L. Vaughan;Carol Sweeney;Marilie D. Gammon

  • NSAIDs Modulate CDKN2A, TP53, and DNA Content Risk for Progression to Esophageal Adenocarcinoma

    Patricia C Galipeau;Xiaohong Li;Patricia L Blount;Patricia L Blount;Carlo C Maley

  • Semen quality of men employed at a lead smelter

    B H Alexander;H Checkoway;C van Netten;C H Muller

Frequent Co-Authors

Marilie D. Gammon
Marilie D. Gammon University of North Carolina at Chapel Hill
Harvey A. Risch
Harvey A. Risch Yale University
Brian J. Reid
Brian J. Reid Fred Hutchinson Cancer Research Center
David C. Whiteman
David C. Whiteman QIMR Berghofer Medical Research Institute
Douglas A. Corley
Douglas A. Corley Kaiser Permanente
Nicholas J. Shaheen
Nicholas J. Shaheen University of North Carolina at Chapel Hill
Anna H. Wu
Anna H. Wu University of Southern California
Weimin Ye
Weimin Ye Karolinska Institute
Wong Ho Chow
Wong Ho Chow The University of Texas MD Anderson Cancer Center
Janet L. Stanford
Janet L. Stanford Fred Hutchinson Cancer Research Center

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