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Jeffrey R. Marks

Jeffrey R. Marks

D-Index & Metrics

Medicine

D-Index
100
Citations
71308
World Ranking
8103
National Ranking
4203

Overview

Jeffrey R. Marks is affiliated with Duke University in the United States. Their research primarily focuses on cancer biology, with particular emphasis on breast cancer and molecular mechanisms underlying cancer progression and treatment outcomes.

The scientist's recent publications explore various aspects of cancer development and recurrence, especially in breast cancer. Notable papers include:

  • Transition to invasive breast cancer is associated with progressive changes in the structure and composition of tumor stroma (2022, Cell)
  • Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer (2022, Nature Genetics)
  • Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts (2022, Cancer Cell)
  • RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence (2020, Cell Death and Differentiation)
  • Tumor-associated nonmyelinating Schwann cell-expressed PVT1 promotes pancreatic cancer kynurenine pathway and tumor immune exclusion (2023, Science Advances)

Their coauthors frequently include Lorraine King, Carlo C. Maley, Lauren C. Peres, Robert B. West, and E. Shelley Hwang.

Jeffrey R. Marks has published extensively in the following venues:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Epidemiology Biomarkers & Prevention
  • Journal of Clinical Oncology
  • npj Breast Cancer

The scientist's work spans several main fields of study:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Subfields of study include:

  • Cancer Research
  • Molecular Biology
  • Oncology
  • Radiology, Nuclear Medicine and Imaging
  • Genetics

Main topics covered in their research are:

  • Cancer Genomics and Diagnostics
  • Breast Cancer Treatment Studies
  • Single-cell and spatial transcriptomics
  • Radiomics and Machine Learning in Medical Imaging
  • Cancer Cells and Metastasis
  • Ovarian cancer diagnosis and treatment
  • BRCA gene mutations in cancer

Their multidisciplinary approach integrates advanced molecular classification techniques with genomic analysis and imaging methodologies. This combination supports an in-depth understanding of tumor biology, cancer recurrence, and treatment resistance in breast cancer and other cancer types.

Best Publications

  • Comprehensive molecular portraits of human breast tumours

    Daniel C. Koboldt;Robert S. Fulton;Michael D. McLellan;Heather Schmidt

  • The Immune Landscape of Cancer

    Vésteinn Thorsson;David L Gibbs;Scott D Brown;Denise Wolf

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Pan-cancer analysis of whole genomes

    Peter J. Campbell;Gad Getz;Jan O. Korbel;Joshua M. Stuart

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Comprehensive Characterization of Cancer Driver Genes and Mutations.

    Matthew H Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • Oncogenic pathway signatures in human cancers as a guide to targeted therapies.

    Andrea H. Bild;Guang Yao;Jeffrey T. Chang;Quanli Wang

  • Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer.

    Giovanni Ciriello;Giovanni Ciriello;Michael L. Gatza;Michael L. Gatza;Andrew H. Beck;Matthew D. Wilkerson

  • Predicting the clinical status of human breast cancer by using gene expression profiles.

    Mike West;Carrie Blanchette;Holly Dressman;Erich Huang

  • BRCA1 mutations in primary breast and ovarian carcinomas

    P. Andrew Futreal;Qingyun Liu;Donna Shattuck-Eidens;Charles Cochran

  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Alison M. Taylor;Alison M. Taylor;Juliann Shih;Gavin Ha;Gavin Ha;Galen F. Gao

  • Young Age at Diagnosis Correlates With Worse Prognosis and Defines a Subset of Breast Cancers With Shared Patterns of Gene Expression

    Carey K. Anders;David S. Hsu;Gloria Broadwater;Chaitanya R. Acharya

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • Pathogenic Germline Variants in 10,389 Adult Cancers

    Kuan-Lin Huang;R Jay Mashl;Yige Wu;Deborah I Ritter

  • Retraction: Genomic signatures to guide the use of chemotherapeutics

    Anil Potti;Holly K Dressman;Andrea Bild;Richard F Riedel

  • Compromised HOXA5 function can limit p53 expression in human breast tumours

    Venu Raman;Shelby A. Martensen;David Reisman;Ella Evron

  • Overexpression and Mutation of p53 in Epithelial Ovarian Cancer

    Jeffrey R. Marks;Andrew M. Davidoff;Billie-Jo M. Kerns;P. A. Humphrey

  • Erratum: Comprehensive Characterization of Cancer Driver Genes and Mutations (ARTICLE (2018) 173(2) (371–385), (S009286741830237X), (10.1016/j.cell.2018.02.060))

    Matthew H. Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • High frequency of hypermethylation at the 14-3-3 σ locus leads to gene silencing in breast cancer

    Anne T. Ferguson;Ella Evron;Christopher B. Umbricht;Tej K. Pandita

  • Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells

    T Baba;T Baba;P A Convery;N Matsumura;N Matsumura;R S Whitaker

Frequent Co-Authors

Andrew Berchuck
Andrew Berchuck Duke University
Joellen M. Schildkraut
Joellen M. Schildkraut University of Virginia
Carlo C. Maley
Carlo C. Maley Arizona State University
Joseph R. Nevins
Joseph R. Nevins Duke University
Robert C. Bast
Robert C. Bast The University of Texas MD Anderson Cancer Center
Joseph Y. Lo
Joseph Y. Lo Duke University
Maciej A. Mazurowski
Maciej A. Mazurowski Duke University
Michael West
Michael West Duke University
Elaine R. Mardis
Elaine R. Mardis The Ohio State University
Matthew Meyerson
Matthew Meyerson Harvard University

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