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Medicine

D-Index
147
Citations
114123
World Ranking
1254
National Ranking
727

Research.com Recognitions

  • 2001 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Robert C. Bast is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research primarily focuses on medical and biochemical fields, with particular emphasis on molecular biology, cancer research, reproductive medicine, oncology, and pulmonary and respiratory medicine.

Bast has contributed extensively to research on ovarian cancer diagnosis and treatment, cancer genomics and diagnostics, autophagy in disease and therapy, molecular mechanisms related to cancer, lipid metabolism in cancer, PARP inhibition in cancer therapy, and the role of ferroptosis in cancer prognosis.

Frequent co-authors in their work include Zhen Lü, Weiqun Mao, Karen H. Lu, Gamze Bildik, and Hailing Yang.

Notable publication venues where Bast has frequently published include Cancer Research, Cancers, Holland-Frei Cancer Medicine, Clinical Cancer Research, and the Journal of Clinical Oncology.

Some recent papers authored or co-authored by Bast are:

  • Biomarkers and Strategies for Early Detection of Ovarian Cancer (2020) in Cancer Epidemiology Biomarkers & Prevention
  • IL-6 promotes drug resistance through formation of polyploid giant cancer cells and stromal fibroblast reprogramming (2021) in Oncogenesis
  • Development of a Multiprotein Classifier for the Detection of Early Stage Ovarian Cancer (2022) in Cancers
  • Targeting progesterone signaling prevents metastatic ovarian cancer (2020) in Proceedings of the National Academy of Sciences
  • DIRAS3: An Imprinted Tumor Suppressor Gene that Regulates RAS and PI3K-driven Cancer Growth, Motility, Autophagy, and Tumor Dormancy (2021) in Molecular Cancer Therapeutics

Awards and honors granted to Bast include election as a Fellow of the American Association for the Advancement of Science (AAAS) in 2001 and membership in the Association of American Physicians.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy

    Daniel J. Klionsky;Fabio C. Abdalla;Hagai Abeliovich;Robert T. Abraham

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer

    Lyndsay Harris;Herbert Fritsche;Robert Mennel;Larry Norton

  • A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancer.

    R C Bast;T L Klug;E St John;E Jenison

  • Reactivity of a monoclonal antibody with human ovarian carcinoma.

    Robert C Bast;M. Feeney;H. Lazarus;L. M. Nadler

  • ASCO 2006 Update of Recommendations for the Use of Tumor Markers in Gastrointestinal Cancer

    Gershon Y. Locker;Stanley R Hamilton;Jules Harris;John M. Jessup

  • The biology of ovarian cancer: new opportunities for translation

    Robert C. Bast;Bryan Hennessy;Gordon B. Mills

  • Rethinking ovarian cancer: recommendations for improving outcomes

    Sebastian Vaughan;Jermaine I. Coward;Robert C. Bast;Andy Berchuck

  • The CA 125 tumour-associated antigen: a review of the literature

    Ian Jacobs;Robert C. Bast

  • Rethinking ovarian cancer II: Reducing mortality from high-grade serous ovarian cancer

    David D. Bowtell;David D. Bowtell;Steffen Böhm;Ahmed A. Ahmed;Paul Joseph Aspuria

  • Three biomarkers identified from serum proteomic analysis for the detection of early stage ovarian cancer

    Zhen Zhang;Robert C. Bast;Yinhua Yu;Jinong Li

  • A novel multiple marker bioassay utilizing HE4 and CA125 for the prediction of ovarian cancer in patients with a pelvic mass

    Richard G. Moore;D. Scott McMeekin;Amy K. Brown;Paul DiSilvestro

  • 2000 Update of Recommendations for the Use of Tumor Markers in Breast and Colorectal Cancer: Clinical Practice Guidelines of the American Society of Clinical Oncology*

    Robert C. Bast;Peter Ravdin;Daniel F. Hayes;Susan Bates

  • The use of multiple novel tumor biomarkers for the detection of ovarian carcinoma in patients with a pelvic mass

    Richard G. Moore;Amy K. Brown;M. Craig Miller;Steven Skates

  • Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women With Early-Stage Invasive Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline

    Lyndsay N. Harris;Nofisat Ismaila;Lisa M. McShane;Fabrice Andre

  • Tumor Marker Utility Grading System: a Framework to Evaluate Clinical Utility of Tumor Markers

    Daniel F. Hayes;Daniel F. Hayes;Robert C. Bast;Christopher E. Desch;Herbert Fritsche

  • Effect of Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor on Hematopoietic Reconstitution after High-Dose Chemotherapy and Autologous Bone Marrow Transplantation

    Stephen J. Brandt;William P. Peters;Susan K. Atwater;Joanne Kurtzberg

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Tissue distribution of a coelomic-epithelium-related antigen recognized by the monoclonal antibody OC125.

    Kabawat Se;Bast Rc;Bhan Ak;Welch Wr

Frequent Co-Authors

Andrew Berchuck
Andrew Berchuck Duke University
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University
Raphael E. Pollock
Raphael E. Pollock The Ohio State University
Ralph R. Weichselbaum
Ralph R. Weichselbaum University of Chicago
Karen H. Lu
Karen H. Lu The University of Texas MD Anderson Cancer Center
Jinsong Liu
Jinsong Liu The University of Texas MD Anderson Cancer Center
Ian Jacobs
Ian Jacobs University of New South Wales
Anil K. Sood
Anil K. Sood The University of Texas MD Anderson Cancer Center
David M. Gershenson
David M. Gershenson The University of Texas MD Anderson Cancer Center
Jonathan S. Berek
Jonathan S. Berek Stanford University

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