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Medicine

D-Index
106
Citations
44515
World Ranking
6489
National Ranking
181

Overview

Ian Jacobs is affiliated with the University of New South Wales in Australia. Their research primarily focuses on medicine, with significant contributions in biochemistry, genetics, and molecular biology. The work covers a range of subfields including reproductive medicine, genetics, oncology, obstetrics and gynecology, and cancer research.

Their research topics predominantly address ovarian cancer diagnosis and treatment, followed by investigations into BRCA gene mutations in cancer, endometrial and cervical cancer treatments, colorectal cancer screening and detection, genetic associations and epidemiology, endometriosis research and treatment, and cancer genomics and diagnostics.

Several recent papers illustrate the scope and focus of their research:

  • Ovarian cancer population screening and mortality after long-term follow-up in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial (2021), The Lancet
  • Ovarian and Breast Cancer Risks Associated With Pathogenic Variants in RAD51C and RAD51D (2020), JNCI Journal of the National Cancer Institute
  • Improved early detection of ovarian cancer using longitudinal multimarker models (2020), British Journal of Cancer
  • Ovarian cancer symptoms, routes to diagnosis and survival - Population cohort study in the 'no screen' arm of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) (2020), Gynecologic Oncology
  • Comprehensive epithelial tubo-ovarian cancer risk prediction model incorporating genetic and epidemiological risk factors (2021), Journal of Medical Genetics

Frequent co-authors collaborating with Ian Jacobs include Usha Menon, Aleksandra Gentry-Maharaj, Matthew Burnell, Andy Ryan, and Jatinderpal Kalsi. These collaborations have led to a substantial number of joint publications spanning clinical trials, genetics, and epidemiological studies.

Their work has been published in several notable academic venues, most frequently in:

  • Cancers
  • bioRxiv (Cold Spring Harbor Laboratory)
  • BJOG An International Journal of Obstetrics & Gynaecology
  • Gynecologic Oncology
  • Health Technology Assessment

Ian Jacobs' research output shows a strong emphasis on cancer-related diseases, particularly ovarian cancer, addressing both clinical and genetic aspects. Their interdisciplinary approach spans diagnostics, treatment, risk prediction, and population screening strategies within the broader field of reproductive medicine and oncology.

Best Publications

  • The CA 125 tumour-associated antigen: a review of the literature

    Ian Jacobs;Robert C. Bast

  • A risk of malignancy index incorporating CA 125, ultrasound and menopausal status for the accurate preoperative diagnosis of ovarian cancer

    I Jacobs;D Oram;J Fairbanks;J Turner

  • Three biomarkers identified from serum proteomic analysis for the detection of early stage ovarian cancer

    Zhen Zhang;Robert C. Bast;Yinhua Yu;Jinong Li

  • Ovarian cancer screening and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial.

    Ian J Jacobs;Ian J Jacobs;Ian J Jacobs;Usha Menon;Andy Ryan;Aleksandra Gentry-Maharaj

  • Epigenetic stem cell signature in cancer.

    Martin Widschwendter;Heidi Fiegl;Heidi Fiegl;Daniel Egle;Elisabeth Mueller-Holzner

  • Menarche, menopause, and breast cancer risk: Individual participant meta-analysis, including 118 964 women with breast cancer from 117 epidemiological studies

    N. Hamajima;K. Hirose;K. Tajima;T. Rohan

  • Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer

    Andrew E. Teschendorff;Usha Menon;Aleksandra Gentry-Maharaj;Susan J. Ramus

  • Management of women who test positive for high-risk types of human papillomavirus: The HART study

    Jack Cuzick;A Szarewski;H Cubie;G Hulman

  • Sensitivity and specificity of multimodal and ultrasound screening for ovarian cancer, and stage distribution of detected cancers: Results of the prevalence screen of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)

    Usha Menon;Aleksandra Gentry-Maharaj;Rachel Hallett;Andy Ryan

  • SCREENING FOR OVARIAN CANCER : A PILOT RANDOMISED CONTROLLED TRIAL

    Ian J. Jacobs;Steven J. Skates;Nicola MacDonald;Usha Menon

  • Ovarian Cancer Population Screening and Mortality After Long-Term Follow-up in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): A Randomised Controlled Trial

    Usha Menon;Aleksandra Gentry-Maharaj;Matthew Burnell;Naveena Singh

  • Progress and Challenges in Screening for Early Detection of Ovarian Cancer

    Ian J. Jacobs;Usha Menon

  • New tumor markers: CA125 and beyond

    Robert C. Bast;D. Badgwell;Z. Lu;R. Marquez

  • Type and timing of menopausal hormone therapy and breast cancer risk: individual participant meta-analysis of the worldwide epidemiological evidence

    N. Hamajima;K. Hirose;K. Tajima;T. Rohan

  • Controlling Molecular Doping in Organic Semiconductors

    Ian E. Jacobs;Adam J. Moulé

  • Prevalence screening for ovarian cancer in postmenopausal women by CA 125 measurement and ultrasonography.

    Ian Jacobs;Ann Prys Davies;Jane Bridges;Isabel Stabile

  • Part 1: Executive summary: 2010 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations.

    Mary Fran Hazinski;Jerry P. Nolan;John E. Billi;Bernd W. Böttiger

  • Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer

    Susan J. Ramus;Honglin Song;Ed Dicks;Jonathan P. Tyrer

  • Diagnostic Performance of Nanoparticle-Enhanced Magnetic Resonance Imaging in the Diagnosis of Lymph Node Metastases in Patients With Endometrial and Cervical Cancer

    Andrea G. Rockall;Syed A. Sohaib;Mukesh G. Harisinghani;Syed A. Babar

  • PTEN methylation is associated with advanced stage and microsatellite instability in endometrial carcinoma.

    Helga B. Salvesen;Helga B. Salvesen;Nicola MacDonald;Andy Ryan;Ian J. Jacobs

Frequent Co-Authors

Usha Menon
Usha Menon University College London
Susan J. Ramus
Susan J. Ramus University of New South Wales
Martin Widschwendter
Martin Widschwendter University College London
Robert C. Bast
Robert C. Bast The University of Texas MD Anderson Cancer Center
Lesley Fallowfield
Lesley Fallowfield University of Sussex
Alistair McGuire
Alistair McGuire London School of Economics and Political Science
Andrew Berchuck
Andrew Berchuck Duke University
Andrew M. Ryan
Andrew M. Ryan University of Michigan–Ann Arbor
Susanne K. Kjaer
Susanne K. Kjaer University of Copenhagen
Paul D.P. Pharoah
Paul D.P. Pharoah University of Cambridge

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