World's Best Scientists 2026 revealed!
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Best Female Scientists
2025

D-Index & Metrics

Best Female Scientists

D-Index
108
Citations
42376
World Ranking
977
National Ranking
595

Medicine

D-Index
112
Citations
45758
World Ranking
5146
National Ranking
2783

Research.com Recognitions

  • 2025 - Research.com Best Female Scientists Award
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Karen H. Lu is affiliated with The University of Texas MD Anderson Cancer Center in the United States. Their research spans multiple fields, primarily focusing on medicine and biochemistry, genetics, and molecular biology. The scientist has contributed extensively to subfields including reproductive medicine, oncology, genetics, obstetrics and gynecology, and cancer research.

The focal topics of their work include ovarian cancer diagnosis and treatment, endometrial and cervical cancer treatments, BRCA gene mutations in cancer, cancer genomics and diagnostics, PARP inhibition in cancer therapy, cancer immunotherapy and biomarkers, and genetic factors in colorectal cancer.

Frequent coauthors in their research encompass Shannon N. Westin, Amir A. Jazaeri, Bryan Fellman, Pamela T. Soliman, and Nicole D. Fleming.

Publications by Karen H. Lu appear regularly in leading venues such as Gynecologic Oncology, Cancer Research, Journal of Clinical Oncology, Clinical Cancer Research, and International Journal of Gynecological Cancer.

Notable recent papers include:

  • Endometrial Cancer, 2020, New England Journal of Medicine
  • Germline and Somatic Tumor Testing in Epithelial Ovarian Cancer: ASCO Guideline, 2020, Journal of Clinical Oncology
  • Molecular Analysis of Clinically Defined Subsets of High-Grade Serous Ovarian Cancer, 2020, Cell Reports
  • Clinical research in ovarian cancer: consensus recommendations from the Gynecologic Cancer InterGroup, 2022, The Lancet Oncology
  • Prospective phase II trial of levonorgestrel intrauterine device: nonsurgical approach for complex atypical hyperplasia and early-stage endometrial cancer, 2020, American Journal of Obstetrics and Gynecology

Karen H. Lu has also been recognized as a member of the Association of American Physicians.

Best Publications

  • Rethinking ovarian cancer II: Reducing mortality from high-grade serous ovarian cancer

    David D. Bowtell;David D. Bowtell;Steffen Böhm;Ahmed A. Ahmed;Paul Joseph Aspuria

  • Prophylactic Surgery to Reduce the Risk of Gynecologic Cancers in the Lynch Syndrome

    Kathleen M. Schmeler;Henry T. Lynch;Lee-May Chen;Mark F. Munsell

  • Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk

    Ganna Chornokur;Hui-Yi Lin;Jonathan P. Tyrer;Kate Lawrenson

  • Recommendations for the care of individuals with an inherited predisposition to Lynch syndrome: a systematic review.

    Noralane M. Lindor;Gloria M. Petersen;Donald W. Hadley;Anita Y. Kinney

  • Grading ovarian serous carcinoma using a two-tier system.

    Anais Malpica;Michael T. Deavers;Karen Lu;Diane C. Bodurka

  • Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer

    Victor Abkevich;Kirsten Timms;Bryan T. Hennessy;Jennifer Potter

  • Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1.

    Chi Lam Au Yeung;Ngai Na Co;Tetsushi Tsuruga;Tsz Lun Yeung

  • New tumor markers: CA125 and beyond

    Robert C. Bast;D. Badgwell;Z. Lu;R. Marquez

  • The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers

    Kwai Wa Cheng;John P. Lahad;Wen Lin Kuo;Anna Lapuk

  • Potential markers that complement expression of CA125 in epithelial ovarian cancer

    Daniel G. Rosen;Lin Wang;J. Neeley Atkinson;Yinhua Yu

  • Selection of Potential Markers for Epithelial Ovarian Cancer with Gene Expression Arrays and Recursive Descent Partition Analysis

    Karen H. Lu;Andrea P. Patterson;Lin Wang;Rebecca T. Marquez

  • Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer.

    Timothy R. Rebbeck;Nandita Mitra;Fei Wan;Olga M. Sinilnikova

  • PI3K/AKT/mTOR Inhibitors in Patients With Breast and Gynecologic Malignancies Harboring PIK3CA Mutations

    Filip Janku;Jennifer J. Wheler;Shannon N. Westin;Stacy L. Moulder

  • Addressing the Role of Obesity in Endometrial Cancer Risk, Prevention, and Treatment

    Michaela A. Onstad;Rosemarie E. Schmandt;Karen H. Lu

  • High Frequency of PIK3R1 and PIK3R2 Mutations in Endometrial Cancer Elucidates a Novel Mechanism for Regulation of PTEN Protein Stability

    Lydia W.T. Cheung;Bryan T. Hennessy;Bryan T. Hennessy;Jie Li;Shuangxing Yu

  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

    Catherine M Phelan;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Jonathan P Tyrer;Siddhartha P Kar

  • Gynecologic cancer as a "sentinel cancer" for women with hereditary nonpolyposis colorectal cancer syndrome.

    Karen H. Lu;Mai Dinh;Wendy Kohlmann;Patrice Watson

  • Somatic Mutations in BRCA1 and BRCA2 Could Expand the Number of Patients That Benefit From Poly (ADP Ribose) Polymerase Inhibitors in Ovarian Cancer

    Bryan T.J. Hennessy;Kirsten M. Timms;Mark S. Carey;Alexander Gutin

  • Hereditary Colorectal Cancer Syndromes: American Society of Clinical Oncology Clinical Practice Guideline Endorsement of the Familial Risk–Colorectal Cancer: European Society for Medical Oncology Clinical Practice Guidelines

    Elena M. Stoffel;Pamela B. Mangu;Stephen B. Gruber;Stanley R. Hamilton

  • Uterine papillary serous carcinoma (UPSC): a single institution review of 129 cases.

    Brian M Slomovitz;Thomas W Burke;Patricia J Eifel;Lois M Ramondetta

Frequent Co-Authors

Russell Broaddus
Russell Broaddus University of North Carolina at Chapel Hill
David M. Gershenson
David M. Gershenson The University of Texas MD Anderson Cancer Center
Robert C. Bast
Robert C. Bast The University of Texas MD Anderson Cancer Center
Samuel C. Mok
Samuel C. Mok The University of Texas MD Anderson Cancer Center
Gordon B. Mills
Gordon B. Mills Oregon Health & Science University
Banu Arun
Banu Arun The University of Texas MD Anderson Cancer Center
Graham G. Giles
Graham G. Giles University of Melbourne
Robert L. Coleman
Robert L. Coleman The University of Texas MD Anderson Cancer Center
Mark F. Munsell
Mark F. Munsell The University of Texas MD Anderson Cancer Center
Pedro Tomas Ramirez
Pedro Tomas Ramirez The University of Texas MD Anderson Cancer Center

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