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D-Index & Metrics

Molecular Biology

D-Index
82
Citations
31152
World Ranking
924
National Ranking
490

Research.com Recognitions

  • 2006 - Member of the National Academy of Sciences
  • 1998 - Fellow of the American Academy of Arts and Sciences

Overview

Carl Wu is affiliated with Johns Hopkins University in the United States. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with a particular focus on Molecular Biology as a subfield. Additional areas of study include Plant Science, Biophysics, Immunology, and Ecology.

The research topics Carl Wu has contributed to include:

  • Genomics and Chromatin Dynamics
  • RNA and protein synthesis mechanisms
  • Diffusion and Search Dynamics
  • RNA Research and Splicing
  • Advanced biosensing and bioanalysis techniques
  • Chromosomal and Genetic Variations
  • DNA and Nucleic Acid Chemistry

Frequent publication venues for Carl Wu's work are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Molecular Cell
  • Biophysical Journal
  • Nature Structural & Molecular Biology

Some of the recent papers published by Carl Wu include:

  • Spatiotemporal coordination of transcription preinitiation complex assembly in live cells, 2021, Molecular Cell
  • Live-cell single particle imaging reveals the role of RNA polymerase II in histone H2A.Z eviction, 2020, eLife
  • Single-molecule imaging of chromatin remodelers reveals role of ATPase in promoting fast kinetics of target search and dissociation from chromatin, 2021, eLife
  • Kinetic principles underlying pioneer function of GAGA transcription factor in live cells, 2022, Nature Structural & Molecular Biology
  • Single-molecule tracking of transcription protein dynamics in living cells: seeing is believing, but what are we seeing?, 2021, Current Opinion in Genetics & Development

The scientist has collaborated frequently with several peers in their research efforts. Notable co-authors include:

  • Taekjip Ha
  • Anand Ranjan
  • Luke D. Lavis
  • Xinyu A. Feng
  • Giho Park

Carl Wu has been recognized with several honors, including membership in the National Academy of Sciences awarded in 2006 and a fellowship at the American Academy of Arts and Sciences since 1998.

Best Publications

  • ATP-Driven Exchange of Histone H2AZ Variant Catalyzed by SWR1 Chromatin Remodeling Complex

    Gaku Mizuguchi;Xuetong Shen;Joe Landry;Wei Hua Wu

  • Heat Shock Transcription Factors: Structure and Regulation

    Carl Wu

  • A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling

    Joanna Wysocka;Tomek Swigut;Hua Xiao;Thomas A. Milne

  • The 5′ ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I

    Carl Wu

  • A chromatin remodelling complex involved in transcription and DNA processing

    Xuetong Shen;Gaku Mizuguchi;Ali Hamiche;Carl Wu

  • ATP-dependent nucleosome disruption at a heat-shock promoter mediated by binding of GAGA transcription factor

    Toshio Tsukiyama;Peter B. Becker;Peter B. Becker;Carl Wu

  • Purification and properties of an ATP-dependent nucleosome remodeling factor.

    Toshio Tsukiyama;Carl Wu

  • Regulation of heat shock factor trimer formation: role of a conserved leucine zipper

    Sridhar K. Rabindran;Raymond I. Haroun;Joachim Clos;Jan Wisniewski

  • Molecular cloning and expression of a human heat shock factor, HSF1.

    Sridhar K. Rabindran;Gisele Giorgi;Joachim Clos;Carl Wu

  • Displacement of sequence-specific transcription factors from mitotic chromatin

    Marian A. Martínez-Balbás;Anup Dey;Sridhar K. Rabindran;Keiko Ozato

  • Protein traffic on the heat shock promoter: Parking, stalling, and trucking along

    John Lis;Carl Wu

  • ISWI, a member of the SWl2/SNF2 ATPase family, encodes the 140 kDa subunit of the nucleosome remodeling factor

    Toshio Tsukiyama;Carla Daniel;John Tamkun;Carl Wu

  • CHARACTERIZATION OF THE IMITATION SWITCH SUBFAMILY OF ATP-DEPENDENT CHROMATIN-REMODELING FACTORS IN SACCHAROMYCES CEREVISIAE

    Toshio Tsukiyama;Jeffrey Palmer;Carolyn C. Landel;Joseph Shiloach

  • Two protein-binding sites in chromatin implicated in the activation of heat-shock genes.

    Carl Wu

  • Fast multicolor 3D imaging using aberration-corrected multifocus microscopy

    Sara Abrahamsson;Sara Abrahamsson;Sara Abrahamsson;Jiji Chen;Bassam Hajj;Sjoerd Stallinga

  • The ISWI chromatin-remodeling protein is required for gene expression and the maintenance of higher order chromatin structure in vivo.

    Renate Deuring;Laura Fanti;Laura Fanti;Jennifer A Armstrong;Melinda Sarte

  • Bending of DNA by gene-regulatory proteins: construction and use of a DNA bending vector

    Jin Kim;Christian W Zwieb;Carl Wu;Sankar Adhya

  • Purification and properties of Drosophila heat shock activator protein.

    Carl Wu;Susan Wilson;Barbara Walker;Igor Dawid

  • Stress-induced oligomerization and chromosomal relocalization of heat-shock factor.

    Westwood Jt;Clos J;Wu C

  • The chromatin structure of specific genes: I. Evidence for higher order domains of defined DNA sequence

    Carl Wu;Paul M. Bingham;Kenneth J. Livak;Robert Holmgren

Frequent Co-Authors

Hua Xiao
Hua Xiao Michigan State University
Toshio Tsukiyama
Toshio Tsukiyama Fred Hutchinson Cancer Research Center
Peter B. Becker
Peter B. Becker Ludwig-Maximilians-Universität München
Sarah C. R. Elgin
Sarah C. R. Elgin Washington University in St. Louis
Feng Wang
Feng Wang Swinburne University of Technology
Rodolfo Ghirlando
Rodolfo Ghirlando National Institutes of Health
C. David Allis
C. David Allis Rockefeller University
Cornelia I. Bargmann
Cornelia I. Bargmann Rockefeller University
David Landsman
David Landsman National Institutes of Health
Robert H. Singer
Robert H. Singer Albert Einstein College of Medicine

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