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Molecular Biology

D-Index
119
Citations
54824
World Ranking
268
National Ranking
158

Research.com Recognitions

  • 2013 - Fellow of the American Academy of Arts and Sciences

Overview

Jerry L. Workman is affiliated with the Stowers Institute for Medical Research in the United States. Their research primarily focuses on the field of Biochemistry, Genetics, and Molecular Biology, with 93 publications in this area. The scientist has contributed extensively to Molecular Biology, Genetics, Plant Science, Immunology, and Geriatrics and Gerontology.

The main topics of their research encompass:

  • RNA modifications and cancer
  • Genomics and Chromatin Dynamics
  • RNA Research and Splicing
  • Epigenetics and DNA Methylation
  • Cancer-related gene regulation
  • Ubiquitin and proteasome pathways
  • RNA and protein synthesis mechanisms

Significant papers authored or co-authored by Jerry L. Workman include:

  • The methyltransferase SETD2 couples transcription and splicing by engaging mRNA processing factors through its SHI domain, 2021, Nature Communications
  • The SAGA chromatin-modifying complex: the sum of its parts is greater than the whole, 2020, Genes & Development
  • The SESAME complex regulates cell senescence through the generation of acetyl-CoA, 2021, Nature Metabolism
  • Regulation of SETD2 stability is important for the fidelity of H3K36me3 deposition, 2020, Epigenetics & Chromatin
  • Paraspeckles interact with SWI/SNF subunit ARID1B to regulate transcription and splicing, 2022, EMBO Reports

The main publication venues where their work frequently appears are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Epigenetics & Chromatin
  • Proceedings of the National Academy of Sciences
  • Genes & Development

Jerry L. Workman has collaborated regularly with other researchers, notably:

  • Laurence Florens
  • Michael P. Washburn
  • Saikat Bhattacharya
  • Tamaki Suganuma
  • Divya Reddy

In recognition of their contributions to science, Jerry L. Workman was elected a Fellow of the American Academy of Arts and Sciences in 2013.

Best Publications

  • The Role of Chromatin during Transcription

    Bing Li;Michael Carey;Jerry L. Workman

  • Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription.

    Michael J. Carrozza;Bing Li;Laurence Florens;Tamaki Suganuma

  • Alteration of Nucleosome Structure as a Mechanism of Transcriptional Regulation

    J L Workman;R E Kingston

  • Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex.

    P A Grant;L Duggan;J Côté;S M Roberts

  • Histone acetyltransferase complexes: one size doesn't fit all

    Kenneth K Lee;Jerry L Workman

  • Stimulation of GAL4 Derivative Binding to Nucleosomal DNA by the Yeast SWI/SNF Complex

    Jacques Côté;Janet Quinn;Jerry L. Workman;Craig L. Peterson

  • New nomenclature for chromatin-modifying enzymes.

    C. David Allis;Shelley L. Berger;Jacques Cote;Sharon R Dent

  • Histone exchange, chromatin structure and the regulation of transcription

    Swaminathan Venkatesh;Jerry L. Workman

  • Purification and biochemical heterogeneity of the mammalian SWI-SNF complex.

    Weidong Wang;Jacques Côté;Yutong Xue;Sharleen Zhou

  • The TAFII250 Subunit of TFIID Has Histone Acetyltransferase Activity

    Craig A. Mizzen;Xiang Jiao Yang;Tetsuro Kokubo;James E. Brownell

  • ATP-dependent chromatin-remodeling complexes.

    Marissa Vignali;Ahmed H. Hassan;Kristen E. Neely;Jerry L. Workman

  • Histone ubiquitination: triggering gene activity.

    Vikki M. Weake;Jerry L. Workman

  • Acetylation by Tip60 Is Required for Selective Histone Variant Exchange at DNA Lesions

    Thomas Kusch;Laurence Florens;W. Hayes MacDonald;Selene K. Swanson

  • Function and Selectivity of Bromodomains in Anchoring Chromatin-Modifying Complexes to Promoter Nucleosomes

    Ahmed H. Hassan;Philippe Prochasson;Kristen E. Neely;Scott C. Galasinski

  • The diverse functions of histone acetyltransferase complexes.

    Michael J. Carrozza;Rhea T. Utley;Jerry L. Workman;Jacques Côté

  • Readers of histone modifications

    Miyong Yun;Jun Wu;Jerry L Workman;Bing Li

  • Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro.

    M Vettese-Dadey;P A Grant;T R Hebbes;C Crane Robinson

  • Transcriptional activators direct histone acetyltransferase complexes to nucleosomes

    Rhea T. Utley;Keiko Ikeda;Patrick A. Grant;Jacques Côté

  • Signals and Combinatorial Functions of Histone Modifications

    Tamaki Suganuma;Jerry L Workman

  • Promoter targeting and chromatin remodeling by the SWI/SNF complex.

    Craig L Peterson;Jerry L Workman

Frequent Co-Authors

Michael P. Washburn
Michael P. Washburn University of Kansas
Laurence Florens
Laurence Florens Stowers Institute for Medical Research
Susan M. Abmayr
Susan M. Abmayr Stowers Institute for Medical Research
Selene K. Swanson
Selene K. Swanson Stowers Institute for Medical Research
Bing Li
Bing Li Shanghai Jiao Tong University
Patrick A. Grant
Patrick A. Grant University of Virginia
Tom Owen-Hughes
Tom Owen-Hughes University of Dundee
David J. Steger
David J. Steger University of Pennsylvania
Sam John
Sam John National Institutes of Health
John R. Yates
John R. Yates Scripps Research Institute

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