2026 Patrick A. Grant: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	45	19047	17458	7775	6928	74	13258

Overview

Patrick A. Grant is affiliated with the University of Virginia in the United States. Their research primarily focuses on the fields of Biochemistry, Genetics, and Molecular Biology, contributing to areas such as Molecular Biology, Genetics, Cellular and Molecular Neuroscience, Nutrition and Dietetics, and Oncology.

The scientist's work encompasses multiple key topics including:

CAR-T cell therapy research
Multiple Myeloma Research and Treatments
Biosimilars and Bioanalytical Methods
Genomics and Chromatin Dynamics
RNA Research and Splicing
RNA and protein synthesis mechanisms
DNA Repair Mechanisms

Recent papers authored or co-authored by Patrick A. Grant include:

The biochemical and genetic discovery of the SAGA complex, 2020, Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
Phase I First-in-Class Trial of MCARH109, a G Protein Coupled Receptor Class C Group 5 Member D (GPRC5D) Targeted CAR T Cell Therapy in Patients with Relapsed or Refractory Multiple Myeloma, 2021, Blood
MYBL2-Driven Transcriptional Programs Link Replication Stress and Error-prone DNA Repair With Genomic Instability in Lung Adenocarcinoma, 2021, Frontiers in Oncology
Transcriptional Profile of Exercise-Induced Protection Against Relapse to Cocaine Seeking in a Rat Model, 2023, Biological Psychiatry Global Open Science
Globally elevated levels of histone H3 lysine 9 trimethylation in early infancy are associated with poor growth trajectory in Bangladeshi children, 2023, Clinical Epigenetics

Frequent co-authors collaborating with Patrick A. Grant include:

David Auble
Kristyna Kupkova
Marilyn G. Pray-Grant
Sham Mailankody
Claudia Diamonte

Patrick A. Grant's publications have appeared in various venues reflecting multidisciplinary interests. These venues include:

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
Blood
Frontiers in Oncology
Biological Psychiatry Global Open Science
Clinical Epigenetics

Best Publications

Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex.

P A Grant;L Duggan;J Côté;S M Roberts

1346
Citations
Set2 Is a Nucleosomal Histone H3-Selective Methyltransferase That Mediates Transcriptional Repression

Brian D Strahl;Patrick A. Grant;Scott D. Briggs;Zu Wen Sun

725
Citations
Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair

Alexander W. Bird;David Y. Yu;Marilyn G. Pray-Grant;Qifeng Qiu

672
Citations
Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro.

M Vettese-Dadey;P A Grant;T R Hebbes;C Crane Robinson

665
Citations
Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation

Marilyn G. Pray-Grant;Jeremy A. Daniel;David Schieltz;John R. Yates

652
Citations
Transcriptional activators direct histone acetyltransferase complexes to nucleosomes

Rhea T. Utley;Keiko Ikeda;Patrick A. Grant;Jacques Côté

642
Citations
NuA4, an essential transcription adaptor/histone H4 acetyltransferase complex containing Esa1p and the ATM-related cofactor Tra1p.

Stéphane Allard;Rhea T. Utley;Julie Savard;Astrid Clarke

586
Citations
A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation.

Patrick A Grant;Patrick A Grant;David Schieltz;Marilyn G Pray-Grant;Marilyn G Pray-Grant;David J Steger;David J Steger

564
Citations
Expanded lysine acetylation specificity of Gcn5 in native complexes.

Patrick A. Grant;Anton Eberharter;Sam John;Richard G. Cook

463
Citations
Functional Organization of the Yeast SAGA Complex: Distinct Components Involved in Structural Integrity, Nucleosome Acetylation, and TATA-Binding Protein Interaction

David E. Sterner;Patrick A. Grant;Shannon M. Roberts;Laura J. Duggan

444
Citations
Deubiquitination of histone H2B by a yeast acetyltransferase complex regulates transcription.

Jeremy A. Daniel;Michael S. Torok;Zu-Wen Sun;David Schieltz

339
Citations
A tale of histone modifications

Patrick A Grant

319
Citations
The Something About Silencing protein, Sas3, is the catalytic subunit of NuA3, a yTAFII30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)–FACT complex

Sam John;LeAnn Howe;Stefan T. Tafrov;Patrick A. Grant

314
Citations
Histone H3 specific acetyltransferases are essential for cell cycle progression

LeAnn Howe;Darryl Auston;Patrick Grant;Sam John

296
Citations
The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.

Marilyn G. Pray-Grant;David Schieltz;Stacey J. McMahon;Jennifer M. Wood

282
Citations
Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.

Chuanbing Bian;Chuanbing Bian;Chao Xu;Jianbin Ruan;Kenneth K. Lee

275
Citations
Sex differences in histone modifications in the neonatal mouse brain

Houng-Wei Tsai;Patrick A. Grant;Emilie F. Rissman

275
Citations
Role of the Ada2 and Ada3 Transcriptional Coactivators in Histone Acetylation

Ramakrishnan Balasubramanian;Marilyn G. Pray-Grant;William Selleck;Patrick A. Grant

271
Citations
The Role of DNA Methylation and Histone Modifications in Transcriptional Regulation in Humans

Jaime L. Miller;Patrick A. Grant

268
Citations
The ATM-Related Cofactor Tra1 Is a Component of the Purified SAGA Complex

Patrick A Grant;David Schieltz;Marilyn G Pray-Grant;John R Yates

263
Citations