World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
135
Citations
63449
World Ranking
352
National Ranking
236

Overview

Donald F. Hunt is a researcher affiliated with the University of Virginia in the United States. Their work spans multiple areas within biochemistry, genetics, and molecular biology, with a strong focus on molecular biology and immunology. Hunt's research encompasses a variety of scientific subfields, including spectroscopy, nuclear and high energy physics, and plant science.

The scientist's recent published papers include a diverse set of studies:

  • Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry (2020, Journal of the American Society for Mass Spectrometry)
  • MHC-restricted phosphopeptide antigens: preclinical validation and first-in-humans clinical trial in participants with high-risk melanoma (2020, Journal for ImmunoTherapy of Cancer)
  • Dark Matter Search Results from 4.2 Tonne−Years of Exposure of the LUX-ZEPLIN (LZ) Experiment (2025, Physical Review Letters)
  • Independent transcriptomic and proteomic regulation by type I and II protein arginine methyltransferases (2021, iScience)
  • Tyrosine Phosphorylation of the Myosin Regulatory Light Chain Controls Non-muscle Myosin II Assembly and Function in Migrating Cells (2020, Current Biology)

Hunt frequently publishes in well-established venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Analytical Chemistry
  • Nature Communications
  • iScience
  • Molecular & Cellular Proteomics

The scientist's collaborative network includes recurring partnerships with several coauthors, notably:

  • Jeffrey Shabanowitz
  • Dina L. Bai
  • Keira E. Mahoney
  • David Shechter
  • Rodolfo Zentella

Donald F. Hunt's investigations address key topics within immunotherapy and immune responses as well as vaccines and immunoinformatics approaches. Other central areas of study include epigenetics and DNA methylation, mass spectrometry techniques and applications, plant molecular biology research, genomics and chromatin dynamics, and advanced proteomics techniques and applications.

Best Publications

  • Peptide and protein sequence analysis by electron transfer dissociation mass spectrometry

    John E. P. Syka;Joshua J. Coon;Melanie J. Schroeder;Jeffrey Shabanowitz

  • Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae

    Scott B Ficarro;Mark L McCleland;P Todd Stukenberg;Daniel J Burke

  • Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry

    Donald F. Hunt;Robert A. Henderson;Jeffrey Shabanowitz;Kazuyasu Sakaguchi

  • Protein sequencing by tandem mass spectrometry

    Donald F. Hunt;John R. Yates;Jeffrey Shabanowitz;Scott Winston

  • Identification of the regulatory phosphorylation sites in pp42/mitogen-activated protein kinase (MAP kinase).

    D. M. Payne;A. J. Rossomando;P. Martino;A. K. Erickson

  • Regulation of HP1–chromatin binding by histone H3 methylation and phosphorylation

    Wolfgang Fischle;Boo Shan Tseng;Holger L. Dormann;Beatrix M. Ueberheide

  • Identification of a peptide recognized by five melanoma-specific human cytotoxic T cell lines

    Andrea L. Cox;Jonathan Skipper;Ye Chen;Robert A. Henderson

  • Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes.

    Jer Yuan Hsu;Zu Wen Sun;Xiumin Li;Melanie Reuben

  • Histone Methyltransferases Direct Different Degrees of Methylation to Define Distinct Chromatin Domains.

    Judd C. Rice;Scott D. Briggs;Beatrix Ueberheide;Cynthia M. Barber

  • Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad

    Donald F. Hunt;Hanspeter Michel;Tracey A. Dickinson;Jeffrey Shabanowitz

  • A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis

    François Dragon;Jennifer E. G. Gallagher;Patricia A. Compagnone-Post;Brianna M. Mitchell

  • Set2 Is a Nucleosomal Histone H3-Selective Methyltransferase That Mediates Transcriptional Repression

    Brian D Strahl;Patrick A. Grant;Scott D. Briggs;Zu Wen Sun

  • Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry

    An Chi;Curtis Huttenhower;Lewis Y. Geer;Joshua J. Coon;Joshua J. Coon

  • HLA-A2.1-associated peptides from a mutant cell line: a second pathway of antigen presentation.

    Robert A. Henderson;Hanspeter Michel;Kazuyasu Sakaguchi;Jeffrey Shabanowitz

  • The utility of ETD mass spectrometry in proteomic analysis.

    Leann M Mikesh;Beatrix Ueberheide;An Chi;Joshua J Coon

  • Gene silencing: Trans -histone regulatory pathway in chromatin

    Scott D. Briggs;Tiaojiang Xiao;Zu Wen Sun;Jennifer A. Caldwell

  • Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation.

    Scott Ficarro;Olga Chertihin;V. Anne Westbrook;Forest White

  • Aurora B Phosphorylates Centromeric MCAK and Regulates Its Localization and Microtubule Depolymerization Activity

    Weijie Lan;Xin Zhang;Susan L Kline-Smith;Sara E Rosasco

  • Methylation of histone H4 at arginine 3 occurs in vivo and is mediated by the nuclear receptor coactivator PRMT1

    Brian D. Strahl;Scott D. Briggs;Cynthia J. Brame;Jennifer A. Caldwell

  • Protein identification using sequential ion/ion reactions and tandem mass spectrometry

    Joshua J. Coon;Beatrix Ueberheide;John E. P. Syka;Deanna D. Dryhurst

Frequent Co-Authors

Jeffrey Shabanowitz
Jeffrey Shabanowitz University of Virginia
Victor H. Engelhard
Victor H. Engelhard University of Virginia
Benjamin A. Garcia
Benjamin A. Garcia Washington University in St. Louis
C. David Allis
C. David Allis Rockefeller University
Craig L. Slingluff
Craig L. Slingluff University of Virginia
Patrick R. Griffin
Patrick R. Griffin Scripps Research Institute
Joshua J. Coon
Joshua J. Coon University of Wisconsin–Madison
John R. Yates
John R. Yates Scripps Research Institute
Ettore Appella
Ettore Appella National Institutes of Health

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Donald F. Hunt

Trending Scientists

Recently Published Articles