What is he best known for?
The fields of study he is best known for:
His primary areas of study are Biochemistry, Receptor, Nuclear receptor, Internal medicine and Endocrinology.
The study of Biochemistry is intertwined with the study of Glucose homeostasis in a number of ways.
As part of the same scientific family, Patrick R. Griffin usually focuses on Receptor, concentrating on RAR-related orphan receptor alpha and intersecting with Retinoic acid and Coactivator.
His Nuclear receptor research includes themes of Peroxisome proliferator-activated receptor, RAR-related orphan receptor gamma, HEK 293 cells, Cell biology and Binding site.
His Peroxisome proliferator-activated receptor research is multidisciplinary, incorporating perspectives in Rosiglitazone, Stereochemistry and Phosphorylation.
His research in Enzyme intersects with topics in Oxidative phosphorylation and Nitric oxide.
His most cited work include:
- Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis (3637 citations)
- A Receptor in Pituitary and Hypothalamus That Functions in Growth Hormone Release (1821 citations)
- Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5 (639 citations)
What are the main themes of his work throughout his whole career to date?
Biochemistry, Receptor, Cell biology, Nuclear receptor and Biophysics are his primary areas of study.
In most of his Biochemistry studies, his work intersects topics such as Molecular biology.
His study in Receptor is interdisciplinary in nature, drawing from both Ligand, Pharmacology and Small molecule.
His research is interdisciplinary, bridging the disciplines of Allosteric regulation and Cell biology.
His work in Nuclear receptor covers topics such as Peroxisome proliferator-activated receptor which are related to areas like Endocrinology.
His study looks at the relationship between Biophysics and topics such as Hydrogen–deuterium exchange, which overlap with Stereochemistry.
He most often published in these fields:
- Biochemistry (24.75%)
- Receptor (19.12%)
- Cell biology (18.38%)
What were the highlights of his more recent work (between 2017-2021)?
- Cell biology (18.38%)
- Receptor (19.12%)
- Nuclear receptor (18.38%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Cell biology, Receptor, Nuclear receptor, Biophysics and Hydrogen–deuterium exchange.
His work deals with themes such as RNA, Helicase, Cell and Small molecule, which intersect with Cell biology.
He combines subjects such as Ligand, Pharmacology and Function with his study of Receptor.
His Nuclear receptor study combines topics from a wide range of disciplines, such as Coactivator, Agonist, Inverse agonist, Nuclear magnetic resonance spectroscopy and In vivo.
As a part of the same scientific family, Patrick R. Griffin mostly works in the field of Inverse agonist, focusing on Peroxisome proliferator-activated receptor and, on occasion, Corepressor.
His research integrates issues of Protein structure, Gap junction, Allosteric regulation and Binding site in his study of Biophysics.
Between 2017 and 2021, his most popular works were:
- Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments. (135 citations)
- HP1 reshapes nucleosome core to promote phase separation of heterochromatin (131 citations)
- Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors (120 citations)
In his most recent research, the most cited papers focused on:
His main research concerns Cell biology, Receptor, Biophysics, Nuclear receptor and Protein structure.
Patrick R. Griffin works in the field of Cell biology, focusing on Signal transduction in particular.
His Receptor study integrates concerns from other disciplines, such as Cell, Retinoic acid and Pharmacology.
His Biophysics research is multidisciplinary, incorporating elements of Coactivator, Peroxisome proliferator-activated receptor, Allosteric regulation and Corepressor.
His Nuclear receptor research incorporates elements of Nuclear magnetic resonance spectroscopy, Binding site and Mass spectrometry.
His Protein structure research incorporates themes from Cytoplasm, Hydrogen–deuterium exchange, Cryo-electron microscopy, Steric effects and Inverse agonist.
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