World's Best Scientists 2026 revealed!
Donald W. Nicholson

Donald W. Nicholson

D-Index & Metrics

Biology and Biochemistry

D-Index
84
Citations
53259
World Ranking
3227
National Ranking
1633

Research.com Recognitions

  • 2007 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Donald W. Nicholson is a researcher affiliated with MSD in the United States. Their work spans multiple scientific disciplines, including psychology, chemistry, and agricultural and biological sciences. Their research contributions reflect a multidisciplinary approach that integrates clinical and organic chemistry perspectives with plant science methodologies.

Their recent publication, titled "Psychedelic-assisted grief therapy: a mixed-method case study", was published in 2024 in the journal Mortality. This paper adds to the study of psychedelic therapies and their potential applications in clinical psychology.

Frequent coauthors collaborating with Nicholson include:

  • Pablo Sabucedo
  • Chris Evans
  • Magí Farré
  • Débora González

The venues where Nicholson has published are currently limited but include the journal Mortality.

The main fields of study associated with Nicholson's work are:

  • Psychology
  • Chemistry
  • Agricultural and Biological Sciences

Within these fields, interested subfields are:

  • Clinical Psychology
  • Organic Chemistry
  • Plant Science

Key research topics explored in Nicholson's publications cover:

  • Psychedelics and Drug Studies
  • Chemical synthesis and alkaloids
  • Natural Compound Pharmacology Studies

In recognition of contributions to science, Nicholson was awarded the title of Fellow of the American Association for the Advancement of Science (AAAS) in 2007.

Best Publications

  • Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

    D W Nicholson;A Ali;N A Thornberry;J P Vaillancourt

  • Caspases: killer proteases

    Donald W. Nicholson;Nancy A. Thornberry

  • Human ICE/CED-3 Protease Nomenclature

    Emad S Alnemri;David J Livingston;Donald W Nicholson;Guy Salvesen

  • A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B FUNCTIONAL RELATIONSHIPS ESTABLISHED FOR KEY MEDIATORS OF APOPTOSIS

    Nancy A. Thornberry;Thomas A. Rano;Erin P. Peterson;Dita M. Rasper

  • Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner.

    Elizabeth A. Slee;Mary T. Harte;Ruth M. Kluck;Beni B. Wolf

  • Caspase structure, proteolytic substrates, and function during apoptotic cell death.

    DW Nicholson

  • Inhibition of Human Caspases by Peptide-based and Macromolecular Inhibitors

    Margarita Garcia-Calvo;Erin P. Peterson;Barbara Leiting;Rejean Ruel

  • Apoptosis and caspases regulate death and inflammation in sepsis

    Richard S. Hotchkiss;Donald W. Nicholson

  • Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B

    Darmon Aj;Nicholson Dw;Bleackley Rc

  • From bench to clinic with apoptosis-based therapeutic agents

    Donald W. Nicholson

  • Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation

    François G. Gervais;Daigen Xu;George S. Robertson;John P. Vaillancourt

  • Mitochondrial protein import.

    Franz-Ulrich Hartl;Nikolaus Pfanner;Donald W. Nicholson;Walter Neupert

  • Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

    L. Galluzzi;L. Galluzzi;L. Galluzzi;S. A. Aaronson;J. Abrams;E. S. Alnemri

  • Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin.

    Rona K. Graham;Yu Deng;Elizabeth J. Slow;Brendan Haigh

  • Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract.

    Y.P. Goldberg;D.W. Nicholson;D.M. Rasper;M.A. Kalchman

  • Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death.

    Livia Casciola-Rosen;Donald W. Nicholson;Tae Chong;Kevin R. Rowan

  • Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte.

    R. S. Hotchkiss;K. C. Chang;P. E. Swanson;K. W. Tinsley

  • Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

    Vanessa S. Marsden;Liam O'Connor;Liam O'Connor;Lorraine A. O'Reilly;John Silke

  • Caspase Cleavage of Gene Products Associated with Triplet Expansion Disorders Generates Truncated Fragments Containing the Polyglutamine Tract

    Cheryl L. Wellington;Lisa M. Ellerby;Abigail S. Hackam;Russell L. Margolis

  • CPP32/apopain is a key interleukin 1 beta converting enzyme-like protease involved in Fas-mediated apoptosis.

    Jörg Schlegel;Iris Peters;Sten Orrenius;Douglas K. Miller

Frequent Co-Authors

Sophie Roy
Sophie Roy MSD (United States)
Nancy A. Thornberry
Nancy A. Thornberry MSD (United States)
Michael R. Hayden
Michael R. Hayden University of British Columbia
Robert Zamboni
Robert Zamboni MSD (United States)
Walter Neupert
Walter Neupert Max Planck Institute of Biochemistry
Anthony W. Ford-Hutchinson
Anthony W. Ford-Hutchinson Independent Scientist / Consultant, US
Joseph A. Mancini
Joseph A. Mancini MSD (United States)
Roshni R. Singaraja
Roshni R. Singaraja Agency for Science, Technology and Research
Antony Rosen
Antony Rosen Johns Hopkins University School of Medicine
Blair R. Leavitt
Blair R. Leavitt University of British Columbia

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Best Scientists Citing Donald W. Nicholson