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Sophie Roy

D-Index & Metrics

Biology and Biochemistry

D-Index
50
Citations
18477
World Ranking
17408
National Ranking
7153

Sophie Roy publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Sophie Roy sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 108 publications — 8th percentile

8% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Sophie Roy D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Sophie Roy sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 50 D-Index — 11th percentile

11% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Sophie Roy is a researcher primarily affiliated with MSD in the United States. Their work spans multiple fields, with significant contributions to Medicine and Biochemistry, Genetics and Molecular Biology. Their research interests focus on various subfields including Immunology, Public Health, Environmental and Occupational Health, Molecular Biology, Oncology, and Genetics.

The scientist has published extensively on topics such as T-cell and B-cell Immunology, Forensic Toxicology and Drug Analysis, Opioid Use Disorder Treatment, Monoclonal and Polyclonal Antibodies Research, CAR-T cell therapy research, Immune Cell Function and Interaction, and Chronic Obstructive Pulmonary Disease (COPD) Research.

Recent publications by Sophie Roy include:

  • Sequential immunotherapy: towards cures for autoimmunity, 2024, Nature Reviews Drug Discovery
  • The fatigue-induced alteration in postural control is larger in hypobaric than in normobaric hypoxia, 2020, Scientific Reports
  • Calcium regulates acid-sensing ion channel 3 activation by competing with protons in the channel pore and at an allosteric binding site, 2022, Open Biology
  • Soluble guanylate cyclase stimulators for the treatment of hypertension: Discovery of MK-2947, 2020, Bioorganic & Medicinal Chemistry Letters
  • Prenatal diagnosis of 2q13 duplications: The crucial role of the family survey in genetic counseling on novel copy number variations, 2020, European Journal of Medical Genetics

Frequent coauthors collaborating with Sophie Roy include:

  • Francisco Ramírez-Valle
  • Joseph Maranville
  • Robert M. Plenge
  • Céline Eiden
  • Marie-Christine Picot

The most common publication venues for this researcher are:

  • Nature Reviews Drug Discovery
  • Therapies
  • Scientific Reports
  • Open Biology
  • Bioorganic & Medicinal Chemistry Letters

Best Publications

  • A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B FUNCTIONAL RELATIONSHIPS ESTABLISHED FOR KEY MEDIATORS OF APOPTOSIS

    Nancy A. Thornberry;Thomas A. Rano;Erin P. Peterson;Dita M. Rasper

  • Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation

    François G. Gervais;Daigen Xu;George S. Robertson;John P. Vaillancourt

  • Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin.

    Rona K. Graham;Yu Deng;Elizabeth J. Slow;Brendan Haigh

  • Malignant transformation by a mutant of the IFN-inducible dsRNA-dependent protein kinase.

    Antonis E. Koromilas;Sophie Roy;Glen N. Barber;Michael G. Katze

  • Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte.

    R. S. Hotchkiss;K. C. Chang;P. E. Swanson;K. W. Tinsley

  • Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

    Vanessa S. Marsden;Liam O'Connor;Liam O'Connor;Lorraine A. O'Reilly;John Silke

  • Caspase Cleavage of Gene Products Associated with Triplet Expansion Disorders Generates Truncated Fragments Containing the Polyglutamine Tract

    Cheryl L. Wellington;Lisa M. Ellerby;Abigail S. Hackam;Russell L. Margolis

  • The Caspase-3 Precursor Has a Cytosolic and Mitochondrial Distribution: Implications for Apoptotic Signaling

    Marie Mancini;Donald W. Nicholson;Sophie Roy;Nancy A. Thornberry

  • A bulge structure in HIV-1 TAR RNA is required for Tat binding and Tat-mediated trans-activation.

    S. Roy;U. Delling;Chein-Hwa Chen;C. A. Rosen

  • Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms

    Maya Saleh;John P. Vaillancourt;Rona K. Graham;Matthew Huyck

  • Caspase-2 Is Localized at the Golgi Complex and Cleaves Golgin-160 during Apoptosis

    Marie Mancini;Carolyn E. Machamer;Sophie Roy;Donald W. Nicholson

  • Caspase Cleavage of Mutant Huntingtin Precedes Neurodegeneration in Huntington's Disease

    Cheryl L. Wellington;Lisa M. Ellerby;Claire-Anne Gutekunst;Danny Rogers

  • Granzyme B Directly and Efficiently Cleaves Several Downstream Caspase Substrates: Implications for CTL-Induced Apoptosis

    Felipe Andrade;Sophie Roy;Donald Nicholson;Nancy Thornberry

  • Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells.

    Cheryl L. Wellington;Roshni Singaraja;Lisa Ellerby;Jane Savill

  • Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex.

    Dita M. Rasper;John P. Vaillancourt;Shinji Hadano;Shinji Hadano;Vicky M. Houtzager

  • Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi.

    François G. Gervais;Roshni Singaraja;Steven Xanthoudakis;Claire-Anne Gutekunst

  • Hsp60 accelerates the maturation of pro-caspase-3 by upstream activator proteases during apoptosis

    Steven Xanthoudakis;Sophie Roy;Dita Rasper;Trevor Hennessey

  • Cross-Talk in Cell Death Signaling

    Sophie Roy;Donald W. Nicholson

  • Caspases cleave focal adhesion kinase during apoptosis to generate a FRNK-like polypeptide.

    François G. Gervais;Nancy A. Thornberry;Salvatore C. Ruffolo;Donald W. Nicholson

  • Maintenance of caspase-3 proenzyme dormancy by an intrinsic “safety catch” regulatory tripeptide

    Sophie Roy;Christopher I. Bayly;Yves Gareau;Vicky M. Houtzager

Frequent Co-Authors

Donald W. Nicholson
Donald W. Nicholson MSD (United States)
Nancy A. Thornberry
Nancy A. Thornberry MSD (United States)
Robert Zamboni
Robert Zamboni MSD (United States)
Michael R. Hayden
Michael R. Hayden University of British Columbia
Gregory J. Kaczorowski
Gregory J. Kaczorowski MSD (United States)
Nahum Sonenberg
Nahum Sonenberg McGill University
Maria L. Garcia
Maria L. Garcia MSD (United States)
Blair R. Leavitt
Blair R. Leavitt University of British Columbia
Antony Rosen
Antony Rosen Johns Hopkins University School of Medicine
Roshni R. Singaraja
Roshni R. Singaraja Agency for Science, Technology and Research

External Links

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Best Scientists Citing Sophie Roy

Michael R. Hayden

Michael R. Hayden

University of British Columbia

Publications: 120

Guy S. Salvesen

Guy S. Salvesen

Sanford Burnham Prebys Medical Discovery Institute

Publications: 101

John C. Reed

John C. Reed

Johnson & Johnson (United States)

Publications: 55

Dale E. Bredesen

Dale E. Bredesen

University of California, Los Angeles

Publications: 52

Andréa C. LeBlanc

Andréa C. LeBlanc

Jewish General Hospital

Publications: 52

Andreas Strasser

Andreas Strasser

Walter and Eliza Hall Institute of Medical Research

Publications: 49

Guido Kroemer

Guido Kroemer

Université Paris Cité

Publications: 47

Boris Zhivotovsky

Boris Zhivotovsky

Karolinska Institute

Publications: 45

Peter Vandenabeele

Peter Vandenabeele

Ghent University

Publications: 44

Douglas R. Green

Douglas R. Green

St. Jude Children's Research Hospital

Publications: 41

Blair R. Leavitt

Blair R. Leavitt

University of British Columbia

Publications: 39

Antony Rosen

Antony Rosen

Johns Hopkins University School of Medicine

Publications: 36

Richard S. Hotchkiss

Richard S. Hotchkiss

Washington University in St. Louis

Publications: 35

Rona K. Graham

Rona K. Graham

Université de Sherbrooke

Publications: 35

Donald W. Nicholson

Donald W. Nicholson

MSD (United States)

Publications: 32

Junying Yuan

Junying Yuan

Harvard University

Publications: 31

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