Andréa C. LeBlanc

Overview

Best Publications

• Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation

  François G. Gervais;Daigen Xu;George S. Robertson;John P. Vaillancourt

  1016
  Citations

• Fatal familial insomnia and familial Creutzfeldt-Jakob disease: disease phenotype determined by a DNA polymorphism

  Lev G. Goldfarb;Robert B. Petersen;Massimo Tabaton;Paul Brown

  898
  Citations

• Fatal Familial Insomnia, a Prion Disease with a Mutation at Codon 178 of the Prion Protein Gene

  Rossella Medori;Hans Juergen Tritschler;Andréa Leblanc;Federico Villare

  796
  Citations

• Selective cytotoxicity of intracellular amyloid β peptide1–42 through p53 and Bax in cultured primary human neurons

  Yan Zhang;Richard McLaughlin;Cynthia Goodyer;Andréa LeBlanc;Andréa LeBlanc

  549
  Citations

• Prion Protein Protects Human Neurons against Bax-mediated Apoptosis

  Younes Bounhar;Yan Zhang;Cynthia G. Goodyer;Andréa LeBlanc

  487
  Citations

• Amyloid β Peptide of Alzheimer’s Disease Downregulates Bcl-2 and Upregulates Bax Expression in Human Neurons

  Eric Paradis;Hélène Douillard;Maria Koutroumanis;Cynthia Goodyer

  422
  Citations

• Testosterone‐mediated neuroprotection through the androgen receptor in human primary neurons

  Jennifer Hammond;Quynh Le;Cynthia Goodyer;Morrie Gelfand

  386
  Citations

• Caspase-6 Role in Apoptosis of Human Neurons, Amyloidogenesis, and Alzheimer’s Disease

  Andréa LeBlanc;Andréa LeBlanc;Hui Liu;Hui Liu;Cynthia Goodyer;Catherine Bergeron

  361
  Citations

• Active Caspase-6 and Caspase-6-Cleaved Tau in Neuropil Threads, Neuritic Plaques, and Neurofibrillary Tangles of Alzheimer's Disease

  Huishan Guo;Steffen Albrecht;Steffen Albrecht;Martine Bourdeau;Tracy Petzke

  346
  Citations

• Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation

  V Kaushal;V Kaushal;R Dye;P Pakavathkumar;P Pakavathkumar;B Foveau;B Foveau

  276
  Citations

• Fatal familial insomnia A second kindred with mutation of prion protein gene at codon 178

  R. Medori;P. Montagna;H. J. Tritschler;A. LeBlanc

  253
  Citations

• Neuroprotective functions of prion protein

  Xavier Roucou;Malcolm Gains;Malcolm Gains;Andréa C LeBlanc;Andréa C LeBlanc

  241
  Citations

• Cytosolic Prion Protein Is Not Toxic and Protects against Bax-mediated Cell Death in Human Primary Neurons

  Xavier Roucou;Qi Guo;Yan Zhang;Cynthia G. Goodyer

  235
  Citations

• Caspase-1 inhibition alleviates cognitive impairment and neuropathology in an Alzheimer's disease mouse model.

  Joseph Flores;Anastasia Noël;Anastasia Noël;Bénédicte Foveau;Jeffrey Lynham;Jeffrey Lynham

  227
  Citations

• Cellular prion protein inhibits proapoptotic Bax conformational change in human neurons and in breast carcinoma MCF-7 cells.

  X Roucou;P N Giannopoulos;Y Zhang;Y Zhang;J Jodoin;J Jodoin

  204
  Citations

• Selective and Protracted Apoptosis in Human Primary Neurons Microinjected with Active Caspase-3, -6, -7, and -8

  Yan Zhang;Cynthia Goodyer;Andréa LeBlanc

  203
  Citations

• Cellular prion protein neuroprotective function: implications in prion diseases

  Xavier Roucou;Andréa C. LeBlanc

  202
  Citations

• Activation of caspase-6 in aging and mild cognitive impairment.

  Steffen Albrecht;Steffen Albrecht;Martine Bourdeau;David Bennett;Elliott J. Mufson

  194
  Citations

• Increased production of 4 kDa amyloid beta peptide in serum deprived human primary neuron cultures: possible involvement of apoptosis

  Andrea LeBlanc

  194
  Citations

• Estrogen and Androgen Protection of Human Neurons against Intracellular Amyloid β1-42 Toxicity through Heat Shock Protein 70

  Yan Zhang;Nathalie Champagne;Lenore K. Beitel;Cynthia G. Goodyer

  185
  Citations