What is he best known for?
The fields of study he is best known for:
Hans A. Kretzschmar mainly focuses on Pathology, Degenerative disease, Frontotemporal lobar degeneration, Amyotrophic lateral sclerosis and Frontotemporal dementia. His Pathology study is mostly concerned with Alzheimer's disease, Anatomical pathology, Tau protein, Neuropathology and Disease. His Degenerative disease research integrates issues from Creutzfeldt-Jakob Syndrome, Dementia, Pathogenesis and Virology.
His Frontotemporal lobar degeneration research is multidisciplinary, relying on both Genetics and Ubiquitin. His studies deal with areas such as Mutation and Progressive supranuclear palsy, Corticobasal degeneration as well as Amyotrophic lateral sclerosis. His studies in Frontotemporal dementia integrate themes in fields like Inclusion bodies, RNA-Binding Protein FUS and Tauopathy.
His most cited work include:
- Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis (4135 citations)
- Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry. (1620 citations)
- The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS (815 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Pathology, Disease, Dementia, Degenerative disease and Biochemistry. Alzheimer's disease, Frontotemporal lobar degeneration, Cerebrospinal fluid, Tau protein and Differential diagnosis are the subjects of his Pathology studies. Hans A. Kretzschmar regularly links together related areas like Amyotrophic lateral sclerosis in his Frontotemporal lobar degeneration studies.
His research investigates the connection between Disease and topics such as Virology that intersect with issues in Gene. His Degenerative disease research is under the purview of Central nervous system disease. His study in Biochemistry is interdisciplinary in nature, drawing from both Oligomer and Amyloid.
He most often published in these fields:
- Pathology (43.34%)
- Disease (17.34%)
- Dementia (11.76%)
What were the highlights of his more recent work (between 2011-2019)?
- Pathology (43.34%)
- Neuroscience (10.22%)
- Neurodegeneration (7.12%)
In recent papers he was focusing on the following fields of study:
Pathology, Neuroscience, Neurodegeneration, Disease and Internal medicine are his primary areas of study. His Pathology study integrates concerns from other disciplines, such as Mutation and Phenotype. His work deals with themes such as Syntaxin and Synaptotagmin 1, which intersect with Neuroscience.
His Neurodegeneration study also includes fields such as
- C9orf72 and related DNA Repeat Expansion,
- Molecular biology most often made with reference to Trinucleotide repeat expansion. Hans A. Kretzschmar has researched Disease in several fields, including Neurology, Genotype and Bioinformatics. The Internal medicine study combines topics in areas such as Gastroenterology, Endocrinology and Oncology.
Between 2011 and 2019, his most popular works were:
- The C9orf72 GGGGCC Repeat Is Translated into Aggregating Dipeptide-Repeat Proteins in FTLD/ALS (815 citations)
- Mutations in the colony stimulating factor 1 receptor ( CSF1R ) gene cause hereditary diffuse leukoencephalopathy with spheroids (325 citations)
- Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins (303 citations)
In his most recent research, the most cited papers focused on:
Hans A. Kretzschmar mainly investigates Pathology, Genetics, Neurodegeneration, C9orf72 and C9orf72 Protein. In most of his Pathology studies, his work intersects topics such as Phenotype. He has included themes like Methylation, Epigenomics, DNA methylation, Mutation and Neuroscience in his Neurodegeneration study.
His biological study spans a wide range of topics, including DNA Repeat Expansion and Amyotrophic lateral sclerosis. His Amyotrophic lateral sclerosis research includes elements of Frontotemporal lobar degeneration, Frontotemporal dementia and Cell biology. The concepts of his Alzheimer's disease study are interwoven with issues in Preclinical imaging, Progressive supranuclear palsy, Retina, Intracellular and Human genetics.
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