Manuela Neumann focuses on Pathology, Frontotemporal lobar degeneration, Amyotrophic lateral sclerosis, Frontotemporal dementia and Ubiquitin. The various areas that she examines in her Pathology study include Neuroscience and Phosphorylation. Her studies in Frontotemporal lobar degeneration integrate themes in fields like Neuropathology, Pathological, RNA-Binding Protein FUS and Genetics.
She works mostly in the field of Amyotrophic lateral sclerosis, limiting it down to concerns involving Neurodegeneration and, occasionally, C9orf72 Protein. Her study in Frontotemporal dementia is interdisciplinary in nature, drawing from both Progressive supranuclear palsy, Anatomical pathology and Gene mutation. She has included themes like Immunohistochemistry, TAR DNA-Binding Protein 43, Monoclonal antibody and Pathogenesis in her Ubiquitin study.
Her primary areas of study are Pathology, Frontotemporal lobar degeneration, Frontotemporal dementia, Amyotrophic lateral sclerosis and Disease. Much of her study explores Pathology relationship to Ubiquitin. The concepts of her Frontotemporal lobar degeneration study are interwoven with issues in Genetics, Pathological, Molecular biology, Cytoplasmic inclusion and Neuroscience.
Her Frontotemporal dementia research is multidisciplinary, incorporating perspectives in Mutation, Gene mutation, Progressive supranuclear palsy and Tau protein. Her Amyotrophic lateral sclerosis research is multidisciplinary, incorporating elements of C9orf72, Neurodegeneration and Spinal cord. Manuela Neumann focuses mostly in the field of Disease, narrowing it down to topics relating to Immunology and, in certain cases, Disease progression and Biomarker.
Pathology, Disease, C9orf72, Cell biology and Neurofilament light are her primary areas of study. Her work carried out in the field of Pathology brings together such families of science as Phenotype and Neuroscience. Her Disease study combines topics from a wide range of disciplines, such as Genetics, Neurofilament and Genotyping.
Her research integrates issues of C9orf72 Protein and Mutation in her study of C9orf72. In her research, Whole genome sequencing is intimately related to Frontotemporal lobar degeneration, which falls under the overarching field of Gene. Her research in Congenic intersects with topics in Internal medicine, Amyotrophic lateral sclerosis and Neurodegeneration.
Her scientific interests lie mostly in Cell biology, Pathology, Disease, Tauopathy and C9orf72. Her biological study spans a wide range of topics, including Arginine, Neurodegeneration and RNA-Binding Protein FUS. Her Alzheimer's disease study, which is part of a larger body of work in Pathology, is frequently linked to Invariant feature, bridging the gap between disciplines.
Her work on Disease progression, Alpha-synuclein and Neurofilament light as part of general Disease research is frequently linked to Intermediate filament, thereby connecting diverse disciplines of science. Her C9orf72 study combines topics in areas such as C9orf72 Protein, Haploinsufficiency, Mutation and Gene isoform. Manuela Neumann combines subjects such as Frontotemporal dementia and Pathogenesis with her study of Trinucleotide repeat expansion.
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Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Manuela Neumann;Deepak M. Sampathu;Linda K. Kwong;Adam C. Truax.
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration
Nigel J. Cairns;Eileen H. Bigio;Ian R A Mackenzie;Manuela Neumann.
Acta Neuropathologica (2007)
Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations
Ian R.A. Mackenzie;Eileen H. Bigio;Paul G. Ince;Felix Geser.
Annals of Neurology (2007)
Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update
Ian R. A. Mackenzie;Manuela Neumann;Eileen H. Bigio;Nigel J. Cairns.
Acta Neuropathologica (2010)
TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
Ian R.A. Mackenzie;Rosa Rademakers;Manuela Neumann.
Lancet Neurology (2010)
A harmonized classification system for FTLD-TDP pathology
Ian R. A. Mackenzie;Manuela Neumann;Atik Baborie;Deepak M. Sampathu.
Acta Neuropathologica (2011)
ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import
Dorothee Dormann;Dorothee Dormann;Ramona Rodde;Ramona Rodde;Dieter Edbauer;Eva Bentmann;Eva Bentmann.
The EMBO Journal (2010)
TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis
Vivianna M. Van Deerlin;James B. Leverenz;James B. Leverenz;Lynn M. Bekris;Thomas D. Bird;Thomas D. Bird.
Lancet Neurology (2008)
A new subtype of frontotemporal lobar degeneration with FUS pathology.
Manuela Neumann;Rosa Rademakers;Sigrun Roeber;Matt Baker.
Subcellular Localization of Wild-Type and Parkinson's Disease-Associated Mutant α-Synuclein in Human and Transgenic Mouse Brain
Philipp J. Kahle;Manuela Neumann;Laurence Ozmen;Veronika Müller.
The Journal of Neuroscience (2000)
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