World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
57
Citations
16522
World Ranking
3374
National Ranking
408

Overview

Nicholas J. Croucher is affiliated with Imperial College London in the United Kingdom and has contributed extensively to the fields of medicine, biochemistry, genetics, and molecular biology. Their research primarily focuses on epidemiology, microbiology, molecular biology, molecular medicine, and genetics. The scientist's work encompasses a range of topics including pneumonia and respiratory infections, bacterial infections and vaccines, respiratory viral infections, genomics and phylogenetic studies, antibiotic resistance in bacteria, influenza virus research, and streptococcal infections and treatments.

The publication record of Nicholas J. Croucher includes several papers appearing in high-impact journals between 2020 and 2024. Notable recent papers include:

  • Divergent serotype replacement trends and increasing diversity in pneumococcal disease in high income settings reduce the benefit of expanding vaccine valency (2020, Scientific Reports)
  • Rapid expansion and international spread of M1UK in the post-pandemic UK upsurge of Streptococcus pyogenes (2024, Nature Communications)
  • Emergence and dissemination of antimicrobial resistance in Escherichia coli causing bloodstream infections in Norway in 2002-17: a nationwide, longitudinal, microbial population genomic study (2021, The Lancet Microbe)
  • Designing ecologically optimized pneumococcal vaccines using population genomics (2020, Nature Microbiology)
  • Visualizing variation within Global Pneumococcal Sequence Clusters (GPSCs) and country population snapshots to contextualize pneumococcal isolates (2020, Microbial Genomics)

Nicholas J. Croucher collaborates frequently with a number of researchers, including:

  • Stephen D. Bentley
  • John A. Lees
  • Jukka Corander
  • Gerry Tonkin-Hill
  • Rebecca A. Gladstone

The scientist's output can be found in a variety of publication venues, predominantly:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Microbial Genomics
  • Genome Research
  • Nature Microbiology
  • SSRN Electronic Journal

Research by Nicholas J. Croucher spans core areas related to respiratory infections and bacterial genomics, with a significant emphasis on vaccine-related studies and antimicrobial resistance. Their work contributes to the understanding of pathogen diversity, vaccine strategy optimization, and tracking of bacterial population genetics on both national and international scales.

Best Publications

  • Rapid phylogenetic analysis of large samples of recombinant bacterial whole genome sequences using Gubbins.

    Nicholas J. Croucher;Andrew J. Page;Thomas R. Connor;Aidan J. Delaney

  • Rapid Pneumococcal Evolution in Response to Clinical Interventions

    Nicholas J. Croucher;Simon R. Harris;Christophe Fraser;Michael A. Quail

  • Evidence for several waves of global transmission in the seventh cholera pandemic

    Ankur Mutreja;Dong Wook Kim;Dong Wook Kim;Nicholas R Thomson;Thomas R Connor

  • Rapid whole-genome sequencing for investigation of a neonatal MRSA outbreak.

    Claudio U. Köser;Claudio U. Köser;Matthew T.G. Holden;Matthew J. Ellington;Edward J P Cartwright;Edward J P Cartwright

  • Phandango: an interactive viewer for bacterial population genomics

    James Hadfield;Nicholas J Croucher;Richard J Goater;Khalil Abudahab

  • Fast and flexible bacterial genomic epidemiology with PopPUNK.

    John A. Lees;Simon R. Harris;Gerry Tonkin-Hill;Rebecca A. Gladstone

  • Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species

    Claudio Donati;N. Luisa Hiller;Hervé Tettelin;Alessandro Muzzi

  • Population genomics of post-vaccine changes in pneumococcal epidemiology

    Nicholas J Croucher;Jonathan A Finkelstein;Jonathan A Finkelstein;Stephen I Pelton;Patrick K Mitchell

  • Dense genomic sampling identifies highways of pneumococcal recombination

    Claire Chewapreecha;Simon R Harris;Nicholas J Croucher;Claudia Turner;Claudia Turner;Claudia Turner

  • Antibiotic treatment of Clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts.

    Trevor D. Lawley;Simon Clare;Alan W. Walker;David Goulding

  • Studying bacterial transcriptomes using RNA-seq

    Nicholas J Croucher;Nicholas R Thomson

  • Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study.

    Stephanie W Lo;Rebecca A Gladstone;Andries J van Tonder;John A Lees

  • Rapid evolution of virulence and drug resistance in the emerging zoonotic pathogen Streptococcus suis

    Matthew T. G. Holden;Heidi Hauser;Mandy Sanders;Thi Hoa Ngo

  • Proteomic and Genomic Characterization of Highly Infectious Clostridium difficile 630 Spores

    Trevor D. Lawley;Nicholas J. Croucher;Lu Yu;Simon Clare

  • Sequence-based analysis uncovers an abundance of non-coding RNA in the total transcriptome of Mycobacterium tuberculosis.

    Kristine B Arnvig;Iñaki Comas;Nicholas R. Thomson;Joanna Houghton

  • A Strand-Specific RNA–Seq Analysis of the Transcriptome of the Typhoid Bacillus Salmonella Typhi

    Timothy T. Perkins;Robert A. Kingsley;Maria C. Fookes;Paul P. Gardner

  • Bayesian inference of ancestral dates on bacterial phylogenetic trees.

    Xavier Didelot;Nicholas J Croucher;Stephen D Bentley;Simon R Harris

  • Comprehensive Identification of Single Nucleotide Polymorphisms Associated with Beta-lactam Resistance within Pneumococcal Mosaic Genes

    Claire Chewapreecha;Pekka Marttinen;Pekka Marttinen;Nicholas J. Croucher;Susannah J. Salter

  • Pneumococcal Capsular Switching: A Historical Perspective

    Kelly L. Wyres;Lotte M. Lambertsen;Nicholas J. Croucher;Lesley McGee

  • Detection of recombination events in bacterial genomes from large population samples

    Pekka Marttinen;William Paul Hanage;Nicholas J. Croucher;Thomas Richard Connor

Frequent Co-Authors

Stephen D. Bentley
Stephen D. Bentley Wellcome Sanger Institute
Jukka Corander
Jukka Corander University of Oslo
Julian Parkhill
Julian Parkhill University of Cambridge
William P. Hanage
William P. Hanage Harvard University
Simon R. Harris
Simon R. Harris Wellcome Sanger Institute
Marc Lipsitch
Marc Lipsitch Harvard University
Christophe Fraser
Christophe Fraser University of Oxford
David M. Aanensen
David M. Aanensen University of Oxford
Keith P. Klugman
Keith P. Klugman Bill & Melinda Gates Foundation
Marco R. Oggioni
Marco R. Oggioni University of Leicester

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