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Immunology

D-Index
57
Citations
10146
World Ranking
3640
National Ranking
250

Overview

Luisa Klotz is affiliated with the University Hospital Münster in Germany and has a prominent publication record in the field of medicine, particularly within neurology and related disciplines. Their research output spans key areas such as pathology and forensic medicine, neurology, immunology, molecular biology, and rheumatology.

Their primary research topics include:

  • Multiple Sclerosis Research Studies
  • Peripheral Neuropathies and Disorders
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Polyomavirus and related diseases
  • Systemic Lupus Erythematosus Research
  • T-cell and B-cell Immunology
  • Rheumatoid Arthritis Research and Therapies

Among recent publications authored or co-authored by Klotz are:

  • Safety and efficacy of rozanolixizumab in patients with generalised myasthenia gravis (MycarinG): a randomised, double-blind, placebo-controlled, adaptive phase 3 study (2023, The Lancet Neurology)
  • Multiple Sclerosis Therapy Consensus Group (MSTCG): position statement on disease-modifying therapies for multiple sclerosis (white paper) (2021, Therapeutic Advances in Neurological Disorders)
  • Update on the diagnosis and treatment of neuromyelitis optica spectrum disorders (NMOSD) - revised recommendations of the Neuromyelitis Optica Study Group (NEMOS). Part I: Diagnosis and differential diagnosis (2023, Journal of Neurology)
  • Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients (2020, Journal of Neuroinflammation)
  • Update on the diagnosis and treatment of neuromyelitis optica spectrum disorders (NMOSD) - revised recommendations of the Neuromyelitis Optica Study Group (NEMOS). Part II: Attack therapy and long-term management (2023, Journal of Neurology)

Klotz has collaborated frequently with several experts in the neurological field, including:

  • Heinz Wiendl (62 collaborations)
  • Sven G. Meuth (40 collaborations)
  • Friedemann Paul (31 collaborations)
  • Catharina C. Groß (29 collaborations)
  • Stefan Bittner (28 collaborations)

Their work is often published in specialized journals, particularly:

  • Neurology
  • Neurology Neuroimmunology & Neuroinflammation
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Neurology
  • Journal of Neurology Neurosurgery & Psychiatry

With a total of 235 publications in medicine, Klotz's research covers a broad spectrum but maintains a strong focus on neurological and immunological aspects related to neuroinflammatory disorders and autoimmune diseases.

Best Publications

  • Gut microbiota from multiple sclerosis patients enables spontaneous autoimmune encephalomyelitis in mice.

    Kerstin Berer;Lisa Ann Gerdes;Egle Cekanaviciute;Xiaoming Jia

  • The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity.

    Luisa Klotz;Sven Burgdorf;Indra Dani;Kaoru Saijo

  • Sodium chloride promotes pro-inflammatory macrophage polarization thereby aggravating CNS autoimmunity.

    Stephanie Hucke;Melanie Eschborn;Marie Liebmann;Martin Herold

  • Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulation.

    Catharina C. Gross;Andreas Schulte-Mecklenbeck;Anna Rünzi;Tanja Kuhlmann

  • Dimethyl fumarate treatment alters circulating T helper cell subsets in multiple sclerosis

    Catharina C. Gross;Andreas Schulte-Mecklenbeck;Svenja Klinsing;Anita Posevitz-Fejfár

  • Peroxisome proliferator-activated receptor gamma control of dendritic cell function contributes to development of CD4+ T cell anergy.

    Luisa Klotz;Indra Dani;Frank Edenhofer;Lars Nolden

  • Peroxisome Proliferator-Activated Receptor-γ Modulates the Response of Macrophages to Lipopolysaccharide and Glucocorticoids

    Michael Heming;Sandra Gran;Saskia-L. Jauch;Lena Fischer-Riepe

  • Cerebrospinal fluid findings in patients with myelin oligodendrocyte glycoprotein (MOG) antibodies. Part 1: Results from 163 lumbar punctures in 100 adult patients

    Sven Jarius;Hannah Pellkofer;Nadja Siebert;Mirjam Korporal-Kuhnke

  • Proinflammatory Stimulation and Pioglitazone Treatment Regulate Peroxisome Proliferator-Activated Receptor γ Levels in Peripheral Blood Mononuclear Cells from Healthy Controls and Multiple Sclerosis Patients

    Luisa Klotz;Martina Schmidt;Thomas Giese;Magdalena Sastre

  • Comparison of switching to 6-week dosing of natalizumab versus continuing with 4-week dosing in patients with relapsing-remitting multiple sclerosis (NOVA): a randomised, controlled, open-label, phase 3b trial

    Unknown

  • CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome.

    Catharina C. Gross;Céline Meyer;Urvashi Bhatia;Lidia Yshii

  • Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects

    Luisa Klotz;Melanie Eschborn;Maren Lindner;Marie Liebmann

  • Nur77 serves as a molecular brake of the metabolic switch during T cell activation to restrict autoimmunity

    Marie Liebmann;Stephanie Hucke;Kathrin Koch;Melanie Eschborn

  • Higher sensitivity in the detection of inflammatory brain lesions in patients with clinically isolated syndromes suggestive of multiple sclerosis using high field MRI: an intraindividual comparison of 1.5 T with 3.0 T.

    Mike P. Wattjes;Götz G. Lutterbey;Michael Harzheim;Jiirgen Gieseke;Jiirgen Gieseke

  • Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells

    Kerstin Göbel;Susann Pankratz;Chloi-Magdalini Asaridou;Alexander M. Herrmann

  • Fingolimod treatment promotes regulatory phenotype and function of B cells

    Berit Grützke;Stephanie Hucke;Catharina C. Gross;Martin V. B. Herold

  • Broader Epstein–Barr virus–specific T cell receptor repertoire in patients with multiple sclerosis

    Unknown

  • Complete Epstein-Barr virus seropositivity in a large cohort of patients with early multiple sclerosis.

    Sargis Abrahamyan;Sargis Abrahamyan;Bettina Eberspächer;Muna-Miriam Hoshi;Lilian Aly

  • Risks and risk management in modern multiple sclerosis immunotherapeutic treatment.

    Luisa Klotz;Joachim Havla;Nicholas Schwab;Reinhard Hohlfeld

  • Ocrelizumab Extended Interval Dosing in Multiple Sclerosis in Times of COVID-19.

    Leoni Rolfes;Marc Pawlitzki;Steffen Pfeuffer;Christopher Nelke

  • Salt-dependent chemotaxis of macrophages.

    Silke Müller;Thomas Quast;Agnes Schröder;Stephanie Hucke

  • Alemtuzumab treatment alters circulating innate immune cells in multiple sclerosis

    Catharina C. Gross;Diana Ahmetspahic;Tobias Ruck;Andreas Schulte-Mecklenbeck

  • Immune mechanisms of new therapeutic strategies in multiple sclerosis-A focus on alemtuzumab.

    Luisa Klotz;Sven G. Meuth;Heinz Wiendl

  • CC chemokine receptor 4 is required for experimental autoimmune encephalomyelitis by regulating GM-CSF and IL-23 production in dendritic cells

    Karola Poppensieker;David-Marian Otte;Britta Schürmann;Andreas Limmer

Frequent Co-Authors

Heinz Wiendl
Heinz Wiendl University of Münster
Sven G. Meuth
Sven G. Meuth University of Münster
Catharina C. Gross
Catharina C. Gross University of Münster
Frauke Zipp
Frauke Zipp Johannes Gutenberg University of Mainz
Ralf Gold
Ralf Gold Ruhr University Bochum
Brigitte Wildemann
Brigitte Wildemann University Hospital Heidelberg
Hayrettin Tumani
Hayrettin Tumani University of Ulm
Friedemann Paul
Friedemann Paul Charité - University Medicine Berlin
Martin Stangel
Martin Stangel Hannover Medical School
Percy A. Knolle
Percy A. Knolle Technical University of Munich

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