World's Best Scientists 2026 revealed!
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Best Scientists
2025
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Immunology
USA
2026

D-Index & Metrics

Best Scientists

D-Index
173
Citations
133687
World Ranking
767
National Ranking
468

Immunology

D-Index
172
Citations
131422
World Ranking
49
National Ranking
36

Medicine

D-Index
175
Citations
135688
World Ranking
426
National Ranking
255

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Best Scientists Award
  • 2025 - Research.com Immunology in United States Leader Award

Overview

Howard L. Weiner is affiliated with Harvard University in the United States and has a prolific publication record in the field of medicine, primarily focusing on neurology and related subfields. Their work spans several interconnected disciplines including immunology, molecular biology, pathology and forensic medicine, and psychiatry and mental health.

They have contributed extensively to research topics such as multiple sclerosis, neuroinflammation, neurodegeneration, epilepsy, gut microbiota, peripheral neuropathies, tryptophan in brain disorders, and Alzheimer's disease research and treatments. The breadth of these topics reflects a deep engagement with neurological disorders and their underlying mechanisms.

Notable recent publications by Howard L. Weiner include:

  • Updated International Tuberous Sclerosis Complex Diagnostic Criteria and Surveillance and Management Recommendations, 2021, Pediatric Neurology
  • Gut microbiome of multiple sclerosis patients and paired household healthy controls reveal associations with disease risk and course, 2022, Cell
  • Blood neurofilament light: a critical review of its application to neurologic disease, 2020, Annals of Clinical and Translational Neurology
  • Gut Microbiome in Progressive Multiple Sclerosis, 2021, Annals of Neurology
  • Locus for severity implicates CNS resilience in progression of multiple sclerosis, 2023, Nature

Howard L. Weiner has published frequently in several scientific journals, with the most frequent venues including:

  • Neurology (31 publications)
  • Journal of Neurosurgery Pediatrics (14 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (12 publications)
  • Epilepsia (9 publications)
  • Multiple Sclerosis and Related Disorders (9 publications)

Collaboration has been a significant part of their academic activity, working closely with co-authors such as:

  • Tanuja Chitnis (92 joint publications)
  • Brian C. Healy (55 joint publications)
  • Bonnie I. Glanz (43 joint publications)
  • Rohit Bakshi (34 joint publications)
  • Laura M. Cox (31 joint publications)

The main fields of study for Howard L. Weiner focus on the medical sciences with a strong specialization in neurology and related life science fields. Their research emphasizes understanding neurological conditions with an interdisciplinary approach involving immunological and molecular biological perspectives.

Best Publications

  • Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells.

    Estelle Bettelli;Yijun Carrier;Wenda Gao;Thomas Korn

  • The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

    Susanne Krasemann;Susanne Krasemann;Charlotte Madore;Ron Cialic;Caroline Baufeld

  • Identification of a unique TGF-β–dependent molecular and functional signature in microglia

    Oleg Butovsky;Mark P Jedrychowski;Craig S Moore;Ron Cialic

  • Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

    Youhai Chen;Vijay K. Kuchroo;Jun-ichi Inobe;David A. Hafler

  • Loss of Functional Suppression by CD4+CD25+ Regulatory T Cells in Patients with Multiple Sclerosis

    Vissia Viglietta;Clare Baecher-Allan;Howard L. Weiner;David A. Hafler

  • B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

    Vijay K Kuchroo;Mercy Prabhu Das;Julia A Brown;Ann M Ranger

  • Control of T reg and T H 17 cell differentiation by the aryl hydrocarbon receptor

    Francisco J. Quintana;Alexandre S. Basso;Antonio H. Iglesias;Thomas Korn

  • Alterations of the human gut microbiome in multiple sclerosis

    Sushrut Jangi;Roopali Gandhi;Laura M. Cox;Ning Li

  • Alemtuzumab versus interferon beta 1a as first-line treatment for patients with relapsing-remitting multiple sclerosis: a randomised controlled phase 3 trial.

    Jeffrey A. Cohen;Alasdair J. Coles;Douglas L. Arnold;Christian Confavreux

  • Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: A randomised controlled phase 3 trial

    Alasdair J. Coles;Cary L. Twyman;Douglas L. Arnold;Jeffrey A. Cohen

  • Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells.

    Howard L. Weiner

  • Oral Tolerance: Immunologic Mechanisms and Treatment of Animal and Human Organ-Specific Autoimmune Diseases by Oral Administration of Autoantigens

    H. L. Weiner;A. Friedman;A. Miller;S. J. Khoury

  • Oral tolerance: immune mechanisms and treatment of autoimmune diseases

    Howard L. Weiner

  • T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis.

    Kohei Ota;Makoto Matsui;Edgar L. Milford;Glenn A. Mackin

  • Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering.

    Ariel Miller;Ofer Lider;Anita B. Roberts;Michael B. Sporn

  • CCR5+ and CXCR3+ T cells are increased in multiple sclerosis and their ligands MIP-1α and IP-10 are expressed in demyelinating brain lesions

    Konstantin E. Balashov;James B. Rottman;Howard L. Weiner;Wayne W. Hancock

  • Microglial signatures and their role in health and disease

    Oleg Butovsky;Howard L. Weiner

  • Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalomyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor beta, interleukin 4, and prostaglandin E expression in the brain.

    S J Khoury;W W Hancock;H L Weiner

  • Multiple Sclerosis: Mechanisms and Immunotherapy

    Clare Baecher-Allan;Belinda J. Kaskow;Howard L. Weiner

  • Intensive immunosuppression in progressive multiple sclerosis. A randomized, three-arm study of high-dose intravenous cyclophosphamide, plasma exchange, and ACTH.

    Hauser Sl;Dawson Dm;Lehrich;Beal Mf

  • Oral tolerance: immune mechanisms and the generation of Th3-type TGF-beta-secreting regulatory cells

    Howard L Weiner

  • Erratum: Identification of a unique TGF-β-dependent molecular and functional signature in microglia (Nature Neuroscience (2014) 17 (131-143))

    Oleg Butovsky;Mark P. Jedrychowski;Craig S. Moore;Ron Cialic

Frequent Co-Authors

David A. Hafler
David A. Hafler Yale University
Samia J. Khoury
Samia J. Khoury American University of Beirut
Tanuja Chitnis
Tanuja Chitnis Harvard University
Rohit Bakshi
Rohit Bakshi Brigham and Women's Hospital
Francisco J. Quintana
Francisco J. Quintana Harvard Medical School
Charles R.G. Guttmann
Charles R.G. Guttmann Brigham and Women's Hospital
Stephen L. Hauser
Stephen L. Hauser University of California, San Francisco
Vijay K. Kuchroo
Vijay K. Kuchroo Harvard University
Philip L. De Jager
Philip L. De Jager Columbia University
Orrin Devinsky
Orrin Devinsky New York University

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