World's Best Scientists 2026 revealed!
David A. Hafler

David A. Hafler

Award Badge
Immunology
USA
2026

D-Index & Metrics

Immunology

D-Index
155
Citations
95828
World Ranking
104
National Ranking
66

Medicine

D-Index
155
Citations
96172
World Ranking
959
National Ranking
550

David A. Hafler publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where David A. Hafler sits on this spectrum.

62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 68 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientists 807+ publications: 100 scientists
62 publications 807+

This scientist: 708 publications — 96th percentile

96% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

David A. Hafler D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where David A. Hafler sits on this spectrum.

40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 162 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40 D-Index 157+

This scientist: 155 D-Index — 98th percentile

98% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Immunology in United States Leader Award
  • 2018 - Member of the National Academy of Medicine (NAM)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

David A. Hafler is affiliated with Yale University in the United States and has contributed extensively to the fields of Medicine and Immunology and Microbiology. Their research spans multiple subfields, including Immunology, Infectious Diseases, Molecular Biology, Neurology, and Oncology.

Their main areas of study focus on immune cell function and interaction, T-cell and B-cell immunology, and COVID-19 clinical research studies. Additional research topics include single-cell and spatial transcriptomics, SARS-CoV-2 and COVID-19 research, immunotherapy and immune responses, and CAR-T cell therapy research.

Key recent publications by David A. Hafler include:

  • Dissection of artifactual and confounding glial signatures by single-cell sequencing of mouse and human brain (2022, Nature Neuroscience)
  • High-plex protein and whole transcriptome co-mapping at cellular resolution with spatial CITE-seq (2023, Nature Biotechnology)
  • Immune dysregulation and autoreactivity correlate with disease severity in SARS-CoV-2-associated multisystem inflammatory syndrome in children (2021, Immunity)
  • Single-cell multi-omics reveals dyssynchrony of the innate and adaptive immune system in progressive COVID-19 (2022, Nature Communications)
  • NEBULA is a fast negative binomial mixed model for differential or co-expression analysis of large-scale multi-subject single-cell data (2021, Communications Biology)

Frequent coauthors collaborating with David A. Hafler include:

  • Steven H. Kleinstein
  • Ruth R. Montgomery
  • Ofer Levy
  • Tomokazu S. Sumida
  • Albert C. Shaw

The scientist has published frequently in venues such as bioRxiv (Cold Spring Harbor Laboratory), ENCODE Datasets, Nature Immunology, Journal of Clinical Investigation, and JCI Insight.

Professional recognition includes membership in prominent organizations such as the National Academy of Medicine since 2018 and the Association of American Physicians.

Best Publications

  • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

    Stephen Sawcer;Garrett Hellenthal;Matti Pirinen;Chris C. A. Spencer

  • FOXP3 + regulatory T cells in the human immune system

    Shimon Sakaguchi;Makoto Miyara;Makoto Miyara;Cristina M. Costantino;Cristina M. Costantino;David A. Hafler;David A. Hafler

  • Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

    Youhai Chen;Vijay K. Kuchroo;Jun-ichi Inobe;David A. Hafler

  • CD4+CD25high Regulatory Cells in Human Peripheral Blood

    Clare Baecher-Allan;Julia A. Brown;Gordon J. Freeman;David A. Hafler

  • Risk alleles for multiple sclerosis identified by a genomewide study.

    David A. Hafler;Alastair Compston;Stephen Sawcer;Mark J. Daly

  • Loss of Functional Suppression by CD4+CD25+ Regulatory T Cells in Patients with Multiple Sclerosis

    Vissia Viglietta;Clare Baecher-Allan;Howard L. Weiner;David A. Hafler

  • Genetic and Epigenetic Fine-Mapping of Causal Autoimmune Disease Variants

    Kyle Kai How Farh;Alexander Marson;Jiang Zhu;Markus Kleinewietfeld

  • Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility

    Unknown

  • Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

    Ashley H. Beecham;Nikolaos A. Patsopoulos;Nikolaos A. Patsopoulos;Dionysia K. Xifara;Mary F. Davis

  • IL-21 and TGF-beta are required for differentiation of human T(H)17 cells.

    Li Yang;David E. Anderson;Clare Baecher-Allan;William D. Hastings

  • Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells

    Markus Kleinewietfeld;Arndt Manzel;Arndt Manzel;Jens Titze;Jens Titze;Heda Kvakan

  • Oral Tolerance: Immunologic Mechanisms and Treatment of Animal and Human Organ-Specific Autoimmune Diseases by Oral Administration of Autoantigens

    H. L. Weiner;A. Friedman;A. Miller;S. J. Khoury

  • T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis.

    Kohei Ota;Makoto Matsui;Edgar L. Milford;Glenn A. Mackin

  • Induction and molecular signature of pathogenic TH17 cells

    Youjin Lee;Amit Awasthi;Amit Awasthi;Nir Yosef;Nir Yosef;Francisco Javier Quintana

  • Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses.

    Nicole Joller;Ester Lozano;Patrick R. Burkett;Bonny Patel

  • Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

    Philip L De Jager;Philip L De Jager;Xiaoming Jia;Joanne Wang;Paul I W de Bakker

  • Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes

    S. Brian Wilson;Sally C. Kent;Kurt T. Patton;Tihamer Orban

  • A high resolution HLA and SNP haplotype map for disease association studies in the extended human MHC

    Paul I W de Bakker;Gil McVean;Pardis C Sabeti;Marcos M Miretti

  • Effects of oral administration of type II collagen on rheumatoid arthritis.

    DE Trentham;RA Dynesius-Trentham;EJ Orav;D Combitchi

  • Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells.

    Ana C. Anderson;David E. Anderson;Lisa Bregoli;William D. Hastings

  • Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis.

    Jingwu Zhang;Silva Markovic-Plese;Blishda Lacet;Jef Raus

Frequent Co-Authors

Howard L. Weiner
Howard L. Weiner Harvard University
Philip L. De Jager
Philip L. De Jager Columbia University
Stephen L. Hauser
Stephen L. Hauser University of California, San Francisco
Vijay K. Kuchroo
Vijay K. Kuchroo Harvard University
Samia J. Khoury
Samia J. Khoury American University of Beirut
Jorge R. Oksenberg
Jorge R. Oksenberg University of California, San Francisco
Stephen Sawcer
Stephen Sawcer University of Cambridge
Kevin C. O’Connor
Kevin C. O’Connor Yale University
John D. Rioux
John D. Rioux University of Montreal
Mark J. Daly
Mark J. Daly Massachusetts General Hospital

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