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Kevin C. O’Connor

Kevin C. O’Connor

D-Index & Metrics

Biology and Biochemistry

D-Index
62
Citations
13306
World Ranking
10833
National Ranking
4701

Overview

Kevin C. O'Connor is affiliated with Yale University in the United States and specializes primarily in the field of Medicine, with a significant focus on Neurology, Immunology, Radiology, Nuclear Medicine and Imaging, Oncology, and Molecular Biology. Their research portfolio includes substantial work related to autoimmune neurological disorders, immunopathology, and cell-based therapies.

O'Connor has contributed to various main topics within these fields, including:

  • Myasthenia Gravis and Thymoma
  • Peripheral Neuropathies and Disorders
  • Monoclonal and Polyclonal Antibodies Research
  • T-cell and B-cell Immunology
  • CAR-T cell therapy research
  • Antifungal resistance and susceptibility
  • Autoimmune Neurological Disorders and Treatments

Their notable recent publications include:

  • "Inflammatory Responses After Ischemic Stroke," 2022, in Seminars in Immunopathology
  • "Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells," 2023, in Nature Biotechnology
  • "Autoimmune Pathology in Myasthenia Gravis Disease Subtypes Is Governed by Divergent Mechanisms of Immunopathology," 2020, in Frontiers in Immunology
  • "The B cell immunobiology that underlies CNS autoantibody-mediated diseases," 2020, in Nature Reviews Neurology
  • "Thymus-derived B cell clones persist in the circulation after thymectomy in myasthenia gravis," 2020, in Proceedings of the National Academy of Sciences

Kevin C. O'Connor frequently publishes in the following venues:

  • Science Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neurology
  • Neurology Neuroimmunology & Neuroinflammation
  • The Journal of Immunology

Their research connections include collaborations with frequent co-authors:

  • Richard J. Nowak
  • Minh Pham
  • Miriam L. Fichtner
  • Gianvito Masi
  • Ruoyi Jiang

Best Publications

  • 5th National Audit Project (NAP5) on accidental awareness during general anaesthesia: summary of main findings and risk factors†‡

    J.J. Pandit;J. Andrade;D.G. Bogod;J.M. Hitchman

  • Comprehensive serological profiling of human populations using a synthetic human virome

    George J. Xu;Tomasz Kula;Tomasz Kula;Qikai Xu;Qikai Xu;Mamie Z. Li;Mamie Z. Li

  • B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes

    Joel N. H. Stern;Gur Yaari;Gur Yaari;Jason A. Vander Heiden;George Church

  • pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires.

    Jason A. Vander Heiden;Gur Yaari;Mohamed Uduman;Joel N.H. Stern

  • Mutation detection using Surveyor nuclease.

    Peter Qiu;Harini Shandilya;James M D'Alessio;Kevin O'Connor

  • Self-antigen tetramers discriminate between myelin autoantibodies to native or denatured protein

    Kevin C O'Connor;Katherine A McLaughlin;Philip L De Jager;Tanuja Chitnis;Tanuja Chitnis

  • MOG cell-based assay detects non-MS patients with inflammatory neurologic disease

    P Waters;M Woodhall;K C O'Connor;M Reindl

  • Relief of expressed suicidal intent by ECT: a consortium for research in ECT study

    Charles H. Kellner;Max Fink;Rebecca Knapp;Georgios Petrides

  • Imaging robust microglial activation after lipopolysaccharide administration in humans with PET

    Christine M. Sandiego;Jean-Dominique Gallezot;Brian Pittman;Nabeel Nabulsi

  • Epstein–Barr virus infection is not a characteristic feature of multiple sclerosis brain

    Simon N. Willis;Christine Stadelmann;Scott J. Rodig;Scott J. Rodig;Tyler Caron;Tyler Caron

  • Dysregulated T cell expression of TIM3 in multiple sclerosis

    Ken Koguchi;David E. Anderson;Li Yang;Kevin C. O'Connor

  • The Neuroimmunology of Multiple Sclerosis: Possible Roles of T and B Lymphocytes in Immunopathogenesis

    Kevin C. O'connor;Amit Bar-Or;David A. Hafler

  • Related B cell clones populate the meninges and parenchyma of patients with multiple sclerosis

    Laura Lovato;Simon N. Willis;Simon N. Willis;Scott J. Rodig;Tyler Caron

  • Models of Somatic Hypermutation Targeting and Substitution Based on Synonymous Mutations from High-Throughput Immunoglobulin Sequencing Data

    Gur Yaari;Gur Yaari;Jason A. Vander Heiden;Mohamed Uduman;Daniel Gadala-Maria

  • Antibodies produced by clonally expanded plasma cells in multiple sclerosis cerebrospinal fluid

    Gregory P. Owens;Jeffrey L. Bennett;Hans Lassmann;Kevin C. O'Connor

  • Age-Dependent B Cell Autoimmunity to a Myelin Surface Antigen in Pediatric Multiple Sclerosis

    Katherine A. McLaughlin;Tanuja Chitnis;Jia Newcombe;Bettina Franz

  • Antibodies from Inflamed Central Nervous System Tissue Recognize Myelin Oligodendrocyte Glycoprotein

    Kevin C. O’Connor;Heiner Appel;Lisa Bregoli;Matthew E. Call

  • Plasma cells in muscle in inclusion body myositis and polymyositis.

    S. A. Greenberg;E. M. Bradshaw;J. L. Pinkus;G. S. Pinkus

  • The neuroinflammation marker translocator protein is not elevated in individuals with mild-to-moderate depression: A [11C]PBR28 PET study

    Jonas Hannestad;Nicole DellaGioia;Jean-Dominique Gallezot;Keunpoong Lim

  • Autoantibodies frequently detected in patients with aplastic anemia.

    Naoto Hirano;Marcus O. Butler;Michael S. von Bergwelt-Baildon;Britta Maecker

Frequent Co-Authors

David A. Hafler
David A. Hafler Yale University
Steven H. Kleinstein
Steven H. Kleinstein Yale University
Amit Bar-Or
Amit Bar-Or University of Pennsylvania
Max Fink
Max Fink Stony Brook University
Patrick Waters
Patrick Waters University of Oxford
Tanuja Chitnis
Tanuja Chitnis Harvard University
Brenda Banwell
Brenda Banwell Children's Hospital of Philadelphia
Anthony A. Amato
Anthony A. Amato Claude Bernard University Lyon 1
Kai W. Wucherpfennig
Kai W. Wucherpfennig Harvard University
Scott J. Rodig
Scott J. Rodig Harvard University

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