Genetics, Immunology, Somatic hypermutation, Cell biology and Antibody are his primary areas of study. His work on Mutation, Acquired immune system and Systems biology as part of general Genetics study is frequently linked to VJ recombination, therefore connecting diverse disciplines of science. His Somatic hypermutation research incorporates themes from Germline mutation, DNA sequencing theory, Computational biology and Sequence analysis.
Steven H. Kleinstein has researched Cell biology in several fields, including Cytotoxic T cell, Regulation of gene expression and Cellular differentiation. Steven H. Kleinstein combines subjects such as Cancer research, Phosphoenolpyruvate carboxykinase and Transforming growth factor beta with his study of Cytotoxic T cell. His Antibody research includes themes of Molecular biology, Immune system and Antigen.
The scientist’s investigation covers issues in Immunology, Somatic hypermutation, Immune system, Antibody and Genetics. His research in Immunology intersects with topics in Disease and Virology. His studies in Somatic hypermutation integrate themes in fields like Negative selection, Computational biology, Selection and Affinity maturation.
The various areas that Steven H. Kleinstein examines in his Immune system study include Molecular biology and Antagonism. His research in Antibody focuses on subjects like Antigen, which are connected to Pathology. His study in the fields of Gene, Mutation, Mutation rate and Germline mutation under the domain of Genetics overlaps with other disciplines such as VJ recombination.
His primary areas of study are B cell, Antibody, Immune system, Immunology and Somatic hypermutation. His B cell study incorporates themes from Myasthenia gravis, Cancer research and Mutation. His work focuses on many connections between Immune system and other disciplines, such as Cytotoxic T cell, that overlap with his field of interest in Immunopathology and Innate immune system.
His Immunology research integrates issues from Asymptomatic and Disease. His Somatic hypermutation study combines topics in areas such as Computational biology and Gene, Affinity maturation. His biological study spans a wide range of topics, including Antigen and Virology.
Steven H. Kleinstein mainly investigates Immune system, Immunology, Antibody, B cell and Virology. His research brings together the fields of Cytotoxic T cell and Immune system. Steven H. Kleinstein studied Immunology and Central nervous system that intersect with Peripheral blood mononuclear cell.
Epitope and Monoclonal antibody are among the areas of Antibody where the researcher is concentrating his efforts. As a member of one scientific family, Steven H. Kleinstein mostly works in the field of Epitope, focusing on Influenza vaccine and, on occasion, Somatic hypermutation. Steven H. Kleinstein studies B cell, namely Germinal center.
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Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.
Ping Chih Ho;Jessica Dauz Bihuniak;Andrew N. MacIntyre;Matthew Staron.
Two levels of protection for the B cell genome during somatic hypermutation
Man Liu;Jamie L. Duke;Daniel J. Richter;Daniel J. Richter;Carola G. Vinuesa.
Germinal Center B Cell and T Follicular Helper Cell Development Initiates in the Interfollicular Zone
Steven M. Kerfoot;Gur Yaari;Jaymin R. Patel;Kody L. Johnson.
B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes
Joel N. H. Stern;Gur Yaari;Gur Yaari;Jason A. Vander Heiden;George Church.
Science Translational Medicine (2014)
Definition of Germinal-Center B Cell Migration In Vivo Reveals Predominant Intrazonal Circulation Patterns
Anja E. Hauser;Tobias Junt;Thorsten R. Mempel;Michael W. Sneddon.
pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires.
Jason A. Vander Heiden;Gur Yaari;Mohamed Uduman;Joel N.H. Stern.
Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data
Namita T. Gupta;Jason A. Vander Heiden;Mohamed Uduman;Daniel Gadala-Maria.
Differential expression of Ly6C and T-bet distinguish effector and memory Th1 CD4(+) cell properties during viral infection.
Heather D. Marshall;Anmol Chandele;Yong Woo Jung;Yong Woo Jung;Hailong Meng.
CD80 and PD-L2 define functionally distinct memory B cell subsets that are independent of antibody isotype
Griselda V Zuccarino-Catania;Saheli Sadanand;Florian J Weisel;Mary M Tomayko.
Nature Immunology (2014)
Antigen-specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity
Krzysztof Bryniarski;Wlodzimierz Ptak;Asha Jayakumar;Kerstin Püllmann.
The Journal of Allergy and Clinical Immunology (2013)
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