What is he best known for?
The fields of study he is best known for:
- Gene
- Immune system
- Antibody
Immunology, Antigen, Autoantibody, Antibody and Autoimmunity are his primary areas of study.
His biological study spans a wide range of topics, including Systemic lupus erythematosus, Graft-versus-host disease and Cell biology.
His Antigen research also works with subjects such as
- B-cell receptor which connect with Chromatin,
- T cell and related B cell,
- Cellular differentiation which is related to area like Somatic hypermutation.
His study in Autoantibody is interdisciplinary in nature, drawing from both Lupus nephritis, Autoimmune disease, Toll-like receptor and CD20.
His studies in Antibody integrate themes in fields like Inflammation, Molecular biology, Spleen and B-1 cell.
His Autoimmunity study combines topics from a wide range of disciplines, such as Mutation, Germline mutation, Immunoglobulin G, Lupus erythematosus and Proinflammatory cytokine.
His most cited work include:
- Chromatin–IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors (1700 citations)
- Prevention of graft versus host disease by inactivation of host antigen-presenting cells. (1087 citations)
- Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. (827 citations)
What are the main themes of his work throughout his whole career to date?
Mark J. Shlomchik mostly deals with Immunology, B cell, Antigen, Cell biology and Antibody.
He regularly ties together related areas like Systemic lupus erythematosus in his Immunology studies.
His B cell research includes themes of Molecular biology and CD40, B-1 cell.
In his research on the topic of Antigen, Chromatin is strongly related with B-cell receptor.
His research integrates issues of Cell, Receptor, breakpoint cluster region, Cellular differentiation and Naive B cell in his study of Cell biology.
His Autoantibody research is multidisciplinary, incorporating perspectives in Transgene, Rheumatoid factor, Inflammation, Proinflammatory cytokine and Autoimmune disease.
He most often published in these fields:
- Immunology (68.40%)
- B cell (39.62%)
- Antigen (28.77%)
What were the highlights of his more recent work (between 2017-2021)?
- Immunology (68.40%)
- B cell (39.62%)
- Germinal center (24.53%)
In recent papers he was focusing on the following fields of study:
Mark J. Shlomchik mainly investigates Immunology, B cell, Germinal center, Antigen and Cell biology.
His work in Immunology is not limited to one particular discipline; it also encompasses Systemic lupus erythematosus.
His B cell study incorporates themes from Molecular biology and Bone marrow.
He interconnects Humoral immunity, Phosphorylation, Affinity maturation and Somatic cell in the investigation of issues within Germinal center.
His Antigen research incorporates elements of Immune system and Immunological memory.
His Cell biology study combines topics in areas such as Receptor, breakpoint cluster region and Naive B cell.
Between 2017 and 2021, his most popular works were:
- To NET or not to NET:current opinions and state of the science regarding the formation of neutrophil extracellular traps. (124 citations)
- B Cell Receptor and CD40 Signaling Are Rewired for Synergistic Induction of the c-Myc Transcription Factor in Germinal Center B Cells (111 citations)
- Kidney-infiltrating T cells in murine lupus nephritis are metabolically and functionally exhausted (40 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Immune system
- Antibody
His primary areas of investigation include Germinal center, Cell biology, Phosphorylation, Antigen and breakpoint cluster region.
His Germinal center study is related to the wider topic of B cell.
His B cell research is multidisciplinary, relying on both mTORC1, Cell signaling and Somatic cell.
The concepts of his Cell biology study are interwoven with issues in Receptor, Major histocompatibility complex and Memory B cell.
His Antigen research includes elements of Myeloid, Immunity, Immunological memory and Heart transplantation.
His research in breakpoint cluster region intersects with topics in Protein kinase B, PTEN, Germline mutation and Protein kinase A.
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