World's Best Scientists 2026 revealed!

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Immunology

D-Index
94
Citations
23823
World Ranking
943
National Ranking
517

Medicine

D-Index
94
Citations
23857
World Ranking
10629
National Ranking
5465

Overview

Geoffrey R. Hill is affiliated with the Fred Hutchinson Cancer Research Center in the United States. Their primary research focus lies in the fields of medicine, with significant contributions to immunology and microbiology. The subfields of study that dominate their work include immunology, hematology, oncology, epidemiology, and molecular biology.

The scientist's publications frequently explore topics such as hematopoietic stem cell transplantation, immune cell function and interaction, T-cell and B-cell immunology, CAR-T cell therapy research, immunotherapy and immune responses, multiple myeloma research and treatments, as well as cytomegalovirus and herpesvirus research.

Key papers authored by Geoffrey R. Hill include:

  • The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation (2020, Nature Immunology)
  • Immunotherapy of multiple myeloma (2020, Journal of Clinical Investigation)
  • Current Concepts and Advances in Graft-Versus-Host Disease Immunology (2021, Annual Review of Immunology)
  • Cytokines and costimulation in acute graft-versus-host disease (2020, Blood)
  • Dissecting the biology of allogeneic HSCT to enhance the GvT effect whilst minimizing GvHD (2020, Nature Reviews Clinical Oncology)

Frequent coauthors collaborating with Geoffrey R. Hill include:

  • Kathleen S. Ensbey
  • Simone A. Minnie
  • Motoko Koyama
  • Scott N. Furlan
  • Ping Zhang

The main venues where their research is published encompass:

  • Blood
  • Transplantation and Cellular Therapy
  • Zenodo (CERN European Organization for Nuclear Research)
  • Journal of Clinical Investigation
  • Immunity

Best Publications

  • Total body irradiation and acute graft-versus-host disease: The role of gastrointestinal damage and inflammatory cytokines

    Geoffrey R. Hill;Geoffrey R. Hill;James M. Crawford;James M. Crawford;Kenneth R. Cooke;Kenneth R. Cooke;Yani S. Brinson;Yani S. Brinson

  • The primacy of the gastrointestinal tract as a target organ of acute graft-versus-host disease: rationale for the use of cytokine shields in allogeneic bone marrow transplantation

    Geoffrey R. Hill;James L. M. Ferrara

  • An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation

    Kelli P. A. MacDonald;James S. Palmer;Stephen Cronau;Elke Jane Seppanen

  • Tumor necrosis factor- alpha production to lipopolysaccharide stimulation by donor cells predicts the severity of experimental acute graft-versus-host disease.

    Kenneth R. Cooke;Geoffrey R. Hill;James M. Crawford;David Bungard

  • LPS antagonism reduces graft-versus-host disease and preserves graft-versus-leukemia activity after experimental bone marrow transplantation.

    Kenneth R. Cooke;Armin Gerbitz;James M. Crawford;Takanori Teshima

  • Interleukin-11 promotes T cell polarization and prevents acute graft-versus-host disease after allogeneic bone marrow transplantation.

    Geoffrey R. Hill;Kenneth R. Cooke;Takanori Teshima;James M. Crawford

  • Chronic graft-versus-host disease: biological insights from preclinical and clinical studies

    Kelli P. A. MacDonald;Geoffrey R. Hill;Geoffrey R. Hill;Bruce R. Blazar

  • Differential roles of IL-1 and TNF-α on graft-versus-host disease and graft versus leukemia

    Geoffrey R. Hill;Takanori Teshima;Takanori Teshima;Armin Gerbitz;Luying Pan

  • Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells.

    Nimitha R Mathew;Nimitha R Mathew;Francis Baumgartner;Lukas Braun;David O'Sullivan

  • TIGIT immune checkpoint blockade restores CD8+ T-cell immunity against multiple myeloma.

    Camille Guillerey;Camille Guillerey;Heidi Harjunpää;Heidi Harjunpää;Nadège Carrié;Sahar Kassem

  • Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease

    Motoko Koyama;Rachel D Kuns;Stuart D Olver;Neil C Raffelt

  • Cytokine cascades in acute graft-versus-host disease.

    Werner Krenger;Geoffrey R. Hill;James L.M. Ferrara

  • Innate immunity defines the capacity of antiviral T cells to limit persistent infection

    Daniel M. Andrews;Marie J. Estcourt;Marie J. Estcourt;Christopher E. Andoniou;Christopher E. Andoniou;Matthew E. Wikstrom;Matthew E. Wikstrom

  • CSF-1–dependant donor-derived macrophages mediate chronic graft-versus-host disease

    Kylie A. Alexander;Ryan Flynn;Katie E. Lineburg;Rachel D. Kuns

  • CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis.

    Alice McNally;Geoffrey R. Hill;Tim Sparwasser;Ranjeny Thomas

  • Increased T follicular helper cells and germinal center B cells are required for cGVHD and bronchiolitis obliterans

    Ryan P Flynn;Jing Du;Rachelle G. Veenstra;Dawn K Reichenbach

  • MHC class II antigen presentation by the intestinal epithelium initiates graft-versus-host disease and is influenced by the microbiota

    Motoko Koyama;Motoko Koyama;Pamela Mukhopadhyay;Iona S. Schuster;Andrea S. Henden

  • IL-11 separates graft-versus-leukemia effects from graft-versus-host disease after bone marrow transplantation

    Takanori Teshima;Geoffrey R. Hill;Luying Pan;Yani S. Brinson

  • Oncogenic JAK2 V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms

    Alessandro Prestipino;Alica J. Emhardt;Konrad Aumann;David O’Sullivan

  • The Colony-Stimulating Factor 1 Receptor Is Expressed on Dendritic Cells during Differentiation and Regulates Their Expansion

    Kelli P A MacDonald;Vanessa Rowe;Helen M Bofinger;Ranjeny Thomas

  • Addition of interleukin-6 inhibition with tocilizumab to standard graft-versus-host disease prophylaxis after allogeneic stem-cell transplantation: a phase 1/2 trial.

    Glen A. Kennedy;Glen A. Kennedy;Antiopi Varelias;Slavica Vuckovic;Laetitia Le Texier

  • A role for natural regulatory T cells in the pathogenesis of experimental cerebral malaria

    Fiona H. Amante;Amanda C. Stanley;Louise M. Randall;Louise M. Randall;Yonghong Zhou

  • Keratinocyte Growth Factor Separates Graft-Versus-Leukemia Effects From Graft-Versus-Host Disease

    Oleg I. Krijanovski;Geoffrey R. Hill;Geoffrey R. Hill;Geoffrey R. Hill;Kenneth R. Cooke;Kenneth R. Cooke;Kenneth R. Cooke;Takanori Teshima;Takanori Teshima;Takanori Teshima

Frequent Co-Authors

Kelli P. A. MacDonald
Kelli P. A. MacDonald QIMR Berghofer Medical Research Institute
Mark J. Smyth
Mark J. Smyth QIMR Berghofer Medical Research Institute
Andrew D. Clouston
Andrew D. Clouston University of Queensland
Bruce R. Blazar
Bruce R. Blazar University of Minnesota
Mariapia A. Degli-Esposti
Mariapia A. Degli-Esposti Monash University
Christian R. Engwerda
Christian R. Engwerda QIMR Berghofer Medical Research Institute
James L.M. Ferrara
James L.M. Ferrara Icahn School of Medicine at Mount Sinai
Kenneth R. Cooke
Kenneth R. Cooke Johns Hopkins University School of Medicine
Jonathan S. Serody
Jonathan S. Serody University of North Carolina at Chapel Hill
Michele W. L. Teng
Michele W. L. Teng QIMR Berghofer Medical Research Institute

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