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Immunology

D-Index
74
Citations
15612
World Ranking
2077
National Ranking
79

Overview

Christian R. Engwerda is affiliated with the QIMR Berghofer Medical Research Institute in Australia. Their research predominantly spans the fields of Medicine and Immunology and Microbiology, with significant focus on Immunology, Public Health, Environmental and Occupational Health, and Epidemiology. Additional specialization includes Molecular Biology and Virology.

The scientist's primary research topics cover Immune Cell Function and Interaction, Research on Leishmaniasis Studies, Malaria Research and Control, Mosquito-borne diseases and control, Trypanosoma species research and implications, HIV Research and Treatment, and T-cell and B-cell Immunology.

Christian R. Engwerda's recent publications include the following works:

  • The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation, 2020, Nature Immunology
  • BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection, 2021, Cell
  • Infection-induced plasmablasts are a nutrient sink that impairs humoral immunity to malaria, 2020, Nature Immunology
  • Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis, 2020, Nature Communications
  • Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis, 2020, Cell Reports

The frequent coauthors with whom Christian R. Engwerda has collaborated include:

  • Michelle J. Boyle
  • Fabian de Labastida Rivera
  • Dean Andrew
  • Jessica R. Loughland
  • Megan S. F. Soon

Their publications are often found in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Immunology
  • SSRN Electronic Journal
  • Zenodo (CERN European Organization for Nuclear Research)
  • Parasite Immunology

Best Publications

  • Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells

    Yulong Gao;Yulong Gao;Fernando Souza-Fonseca-Guimaraes;Fernando Souza-Fonseca-Guimaraes;Fernando Souza-Fonseca-Guimaraes;Tobias Bald;Susanna S Ng;Susanna S Ng

  • DENDRITIC CELLS, BUT NOT MACROPHAGES, PRODUCE IL-12 IMMEDIATELY FOLLOWING LEISHMANIA DONOVANI INFECTION

    Patricia M. A. Gorak;Christian R. Engwerda;Paul M. Kaye

  • Locally Up-regulated Lymphotoxin α, Not Systemic Tumor Necrosis Factor α, Is the Principle Mediator of Murine Cerebral Malaria

    Christian R. Engwerda;Tracey L. Mynott;Sanjeet Sawhney;J. Brian De Souza

  • Balancing immunity and pathology in visceral leishmaniasis.

    Amanda C Stanley;Christian R Engwerda

  • Single-cell RNA-seq and computational analysis using temporal mixture modelling resolves Th1/Tfh fate bifurcation in malaria

    Tapio Lönnberg;Tapio Lönnberg;Valentine Svensson;Kylie R. James;Daniel Fernandez-Ruiz

  • The immunopathology of experimental visceral leishmaniasis

    Paul M. Kaye;Mattias Svensson;Manabu Ato;Asher Maroof

  • Recipient nonhematopoietic antigen-presenting cells are sufficient to induce lethal acute graft-versus-host disease

    Motoko Koyama;Rachel D Kuns;Stuart D Olver;Neil C Raffelt

  • The importance of the spleen in malaria

    Christian R. Engwerda;Lynette Beattie;Fiona H. Amante

  • B Cell-Deficient Mice Are Highly Resistant to Leishmania donovani Infection, but Develop Neutrophil-Mediated Tissue Pathology

    Sara C. Smelt;Sara E. J. Cotterell;Christian R. Engwerda;Paul M. Kaye

  • Bone marrow-derived and resident liver macrophages display unique transcriptomic signatures but similar biological functions

    Lynette Beattie;Lynette Beattie;Amy Sawtell;Jason L. Mann;Teija C.M. Frame

  • Development and regulation of cell-mediated immune responses to the blood stages of malaria: implications for vaccine research

    Michael Francis Good;Huji Xu;Michelle Wykes;Christian R. Engwerda

  • CSF-1–dependant donor-derived macrophages mediate chronic graft-versus-host disease

    Kylie A. Alexander;Ryan Flynn;Katie E. Lineburg;Rachel D. Kuns

  • Macrophages, pathology and parasite persistence in experimental visceral leishmaniasis

    Christian R. Engwerda;Manabu Ato;Paul M. Kaye

  • Defective CCR7 expression on dendritic cells contributes to the development of visceral leishmaniasis.

    Manabu Ato;Simona Stäger;Christian R. Engwerda;Paul M. Kaye

  • Granzyme B Expression by CD8+ T Cells Is Required for the Development of Experimental Cerebral Malaria

    Ashraful Haque;Shannon E. Best;Klara Unosson;Fiona H. Amante

  • Organ-specific immune responses associated with infectious disease.

    Christian R Engwerda;Paul M Kaye

  • A role for natural regulatory T cells in the pathogenesis of experimental cerebral malaria

    Fiona H. Amante;Amanda C. Stanley;Louise M. Randall;Louise M. Randall;Yonghong Zhou

  • Vaccines to prevent leishmaniasis

    Rajiv Kumar;Christian Engwerda

  • Immune-Mediated Mechanisms of Parasite Tissue Sequestration during Experimental Cerebral Malaria

    Fiona H Amante;Ashraful K M Nazmul Haque;Amanda C Stanley;Fabian De Labastida Rivera

  • IFNγ differentially controls the development of idiopathic pneumonia syndrome and GVHD of the gastrointestinal tract

    Angela C. Burman;Tatjana Banovic;Rachel D. Kuns;Andrew D. Clouston

Frequent Co-Authors

Geoffrey R. Hill
Geoffrey R. Hill Fred Hutchinson Cancer Research Center
James S. McCarthy
James S. McCarthy Walter and Eliza Hall Institute of Medical Research
Paul M. Kaye
Paul M. Kaye Hull York Medical School
Michael F. Good
Michael F. Good Griffith University
Kelli P. A. MacDonald
Kelli P. A. MacDonald QIMR Berghofer Medical Research Institute
Mark J. Smyth
Mark J. Smyth QIMR Berghofer Medical Research Institute
Nicholas M. Anstey
Nicholas M. Anstey Charles Darwin University
Ric N. Price
Ric N. Price Charles Darwin University
Shyam Sundar
Shyam Sundar Banaras Hindu University
Andrew D. Clouston
Andrew D. Clouston University of Queensland

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