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Biology and Biochemistry

D-Index
89
Citations
20388
World Ranking
2631
National Ranking
1370

Overview

Robert L. Tanguay is affiliated with Oregon State University in the United States and has contributed extensively to research in biochemistry, genetics, molecular biology, medicine, and environmental science. Their work spans multiple subfields, primarily focusing on health, toxicology, mutagenesis, molecular biology, cell biology, public health, environmental and occupational health, and physiology.

Their research revolves around key topics such as zebrafish biomedical research applications, toxic organic pollutants impact, environmental toxicology and ecotoxicology, effects and risks of endocrine disrupting chemicals, opioid use disorder treatment, prenatal substance exposure effects, and animal testing and alternatives.

Tanguay's recent publications document a range of studies with implications in environmental and developmental toxicology, including:

  • Environmental relevant concentrations of benzophenone-3 induced developmental neurotoxicity in zebrafish, 2020, The Science of The Total Environment
  • Systematic developmental toxicity assessment of a structurally diverse library of PFAS in zebrafish, 2022, Journal of Hazardous Materials
  • The chemistry and toxicology of vaping, 2021, Pharmacology & Therapeutics
  • Behavior Effects of Structurally Diverse Per- and Polyfluoroalkyl Substances in Zebrafish, 2021, Chemical Research in Toxicology
  • The Zebrafish Xenograft Models for Investigating Cancer and Cancer Therapeutics, 2021, Biology

Tanguay's frequent co-authors include Lisa Truong, Michael T. Simonich, David M. Reif, Yvonne Rericha, and Katrina M. Waters. Collaboration with these researchers highlights an interdisciplinary approach to toxicology, environmental science, and molecular biology research.

Their work has been published repeatedly in several notable scientific venues, such as:

  • Toxics
  • Toxicological Sciences
  • Journal of Obstetrics and Gynaecology Canada
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Toxicology

Overall, Tanguay's research portfolio reflects a sustained focus on developmental and environmental toxicology using zebrafish as a model organism. Their investigations contribute to understanding the biological effects of various chemical exposures, particularly per- and polyfluoroalkyl substances (PFAS), endocrine disruptors, and other toxic organic pollutants, which are relevant for public and environmental health.

Best Publications

  • Sulfidation of silver nanoparticles: natural antidote to their toxicity.

    Clement Levard;Clement Levard;Clement Levard;Ernest M. Hotze;Ernest M. Hotze;Benjamin P. Colman;Amy L. Dale;Amy L. Dale

  • In vivo evaluation of carbon fullerene toxicity using embryonic zebrafish

    Crystal Y. Usenko;Stacey L. Harper;Robert L. Tanguay

  • Translation Initiation Factors eIF-iso4G and eIF-4B Interact with the Poly(A)-binding Protein and Increase Its RNA Binding Activity*

    Hanh Le;Robert L. Tanguay;M. Luisa Balasta;Chin Chuan Wei

  • Multidimensional in Vivo Hazard Assessment Using Zebrafish

    Lisa Truong;David M. Reif;Lindsey St Mary;Mitra C. Geier

  • Toxicity, uptake kinetics and behavior assessment in zebrafish embryos following exposure to perfluorooctanesulphonicacid (PFOS).

    Haihua Huang;Changjiang Huang;Lijun Wang;Xiaowei Ye

  • Translational efficiency is regulated by the length of the 3' untranslated region.

    R L Tanguay;D R Gallie

  • Evaluation of Embryotoxicity Using the Zebrafish Model

    Lisa Truong;Stacey L. Harper;Robert L. Tanguay

  • Fullerene C60 exposure elicits an oxidative stress response in embryonic zebrafish.

    Crystal Y. Usenko;Stacey L. Harper;Robert L. Tanguay

  • Advancements in zebrafish applications for 21st century toxicology.

    Gloria R. Garcia;Pamela D. Noyes;Robert L. Tanguay

  • Tissue-Specific Expression of AHR2, ARNT2, and CYP1A in Zebrafish Embryos and Larvae: Effects of Developmental Stage and 2,3,7,8-Tetrachlorodibenzo-p-dioxin Exposure

    Eric A. Andreasen;Jan M. Spitsbergen;Robert L. Tanguay;John J. Stegeman

  • Neurodevelopmental low-dose bisphenol A exposure leads to early life-stage hyperactivity and learning deficits in adult zebrafish.

    Katerine S. Saili;Margaret M. Corvi;Daniel N. Weber;Ami U. Patel

  • Comparative developmental toxicity of environmentally relevant oxygenated PAHs

    Andrea L. Knecht;Britton C. Goodale;Lisa Truong;Michael T. Simonich

  • Ethanol- and acetaldehyde-mediated developmental toxicity in zebrafish.

    Mark J. Reimers;Amanda R. Flockton;Robert L. Tanguay

  • Cloning and characterization of the zebrafish (Danio rerio) aryl hydrocarbon receptor.

    Robert L. Tanguay;Christian C. Abnet;Warren Heideman;Richard E. Peterson

  • The zebrafish (Danio rerio) aryl hydrocarbon receptor type 1 is a novel vertebrate receptor.

    Eric A. Andreasen;Mark E. Hahn;Warren Heideman;Richard E. Peterson

  • Systematic Evaluation of Nanomaterial Toxicity: Utility of Standardized Materials and Rapid Assays

    Stacey L. Harper;Jason Lee Carriere;Jason Lee Carriere;John M. Miller;James Evan Hutchison

  • Polycyclic aromatic hydrocarbons in water, sediment, soil, and plants of the Aojiang River waterway in Wenzhou, China.

    Jianwang Li;Xu Shang;Zhixu Zhao;Robert L. Tanguay;Robert L. Tanguay

  • Automated Zebrafish Chorion Removal and Single Embryo Placement: Optimizing Throughput of Zebrafish Developmental Toxicity Screens

    David Mandrell;Lisa Truong;Caleb Jephson;Mushfiqur R. Sarker

  • Repression of Aryl Hydrocarbon Receptor (AHR) Signaling by AHR Repressor: Role of DNA Binding and Competition for AHR Nuclear Translocator

    Brad R. Evans;Sibel I. Karchner;Lenka L. Allan;Richard S. Pollenz

  • Gold nanoparticles disrupt zebrafish eye development and pigmentation.

    Ki-Tae Kim;Tatiana Zaikova;James E. Hutchison;Robert L. Tanguay

Frequent Co-Authors

Katrina M. Waters
Katrina M. Waters Pacific Northwest National Laboratory
Maret G. Traber
Maret G. Traber Oregon State University
Staci L. Massey Simonich
Staci L. Massey Simonich Oregon State University
James E. Hutchison
James E. Hutchison University of Oregon
Daniel R. Gallie
Daniel R. Gallie University of California, Riverside
Kim A. Anderson
Kim A. Anderson Oregon State University
Richard E. Peterson
Richard E. Peterson University of Wisconsin–Madison
Nancy I. Kerkvliet
Nancy I. Kerkvliet Oregon State University
Jan F. Stevens
Jan F. Stevens Oregon State University
Warren Heideman
Warren Heideman University of Wisconsin–Madison

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