D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 41 Citations 14,814 70 World Ranking 15903 National Ranking 6596

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Genetics

His primary areas of study are Gene silencing, RNA interference, Small interfering RNA, Pharmacology and In vivo. Antonin de Fougerolles has included themes like Molecular biology and Computational biology in his RNA interference study. His Small interfering RNA study is concerned with the larger field of RNA.

The various areas that Antonin de Fougerolles examines in his RNA study include Nucleic acid and Rational design. His In vivo research includes elements of Receptor, Biochemistry, Gene, Endogeny and Apolipoprotein E. Many of his research projects under Biochemistry are closely connected to Primary and Asialoglycoprotein receptor with Primary and Asialoglycoprotein receptor, tying the diverse disciplines of science together.

His most cited work include:

  • Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. (1129 citations)
  • Rational design of cationic lipids for siRNA delivery (1089 citations)
  • Interfering with disease: a progress report on siRNA-based therapeutics. (1004 citations)

What are the main themes of his work throughout his whole career to date?

Antonin de Fougerolles focuses on Biochemistry, Polynucleotide, Molecular biology, Nucleic acid and Cell biology. In his research, Cell, Nucleic acid molecule and A protein is intimately related to Function, which falls under the overarching field of Biochemistry. His work is dedicated to discovering how Polynucleotide, Stereochemistry are connected with Untranslated region and other disciplines.

His Molecular biology research is multidisciplinary, incorporating elements of RNA, RNA interference, Gene, Immunoglobulin superfamily and Intercellular adhesion molecule. The study incorporates disciplines such as Gene silencing and Virology in addition to RNA. His Gene silencing study incorporates themes from Cancer research, Computational biology, In vivo and RNAi Therapeutics.

He most often published in these fields:

  • Biochemistry (43.10%)
  • Polynucleotide (42.24%)
  • Molecular biology (24.14%)

What were the highlights of his more recent work (between 2012-2020)?

  • Polynucleotide (42.24%)
  • Biochemistry (43.10%)
  • Nucleic acid (21.55%)

In recent papers he was focusing on the following fields of study:

Antonin de Fougerolles mostly deals with Polynucleotide, Biochemistry, Nucleic acid, Stereochemistry and Molecular biology. His work deals with themes such as Messenger RNA, Immunology and Cell biology, which intersect with Polynucleotide. His work on Protein biosynthesis as part of general Biochemistry study is frequently linked to Molecule, bridging the gap between disciplines.

His study on Nucleic acid also encompasses disciplines like

  • Sequence that connect with fields like Nucleoside,
  • Nucleotide together with Sequence identity. The Molecular biology study combines topics in areas such as RNA and Cytotoxic T cell. His research integrates issues of Polymerase and Enzyme in his study of RNA.

Between 2012 and 2020, his most popular works were:

  • Modified polynucleotides for the production of biologics and proteins associated with human disease (179 citations)
  • Modified polynucleotides for the production of proteins associated with human disease (138 citations)
  • Terminally modified rna (134 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Biochemistry

His scientific interests lie mostly in Polynucleotide, Biochemistry, Primary, Nucleic acid and Molecular biology. His Polynucleotide study combines topics from a wide range of disciplines, such as RNA, Immunology and Cell biology. His work carried out in the field of RNA brings together such families of science as Polymerase, Enzyme and Stereochemistry.

His Biochemistry research incorporates themes from UDP glucuronosyltransferase 1 family, polypeptide A1 and Function. He interconnects Protein subcellular localization prediction and Nucleoside in the investigation of issues within Nucleic acid. His studies in Molecular biology integrate themes in fields like Cellular receptor and Virology.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7.

Veit Hornung;Margit Guenthner-Biller;Carole Bourquin;Andrea Ablasser.
Nature Medicine (2005)

1553 Citations

Interfering with disease: a progress report on siRNA-based therapeutics.

Antonin de Fougerolles;Hans Peter Vornlocher;John Maraganore;Judy Lieberman.
Nature Reviews Drug Discovery (2007)

1378 Citations

Rational design of cationic lipids for siRNA delivery

Sean C Semple;Akin Akinc;Jianxin Chen;Ammen P Sandhu.
Nature Biotechnology (2010)

1289 Citations

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

Akin Akinc;Andreas Zumbuehl;Andreas Zumbuehl;Michael Goldberg;Elizaveta S Leshchiner.
Nature Biotechnology (2008)

1068 Citations

Lipid-like materials for low-dose, in vivo gene silencing

Kevin T. Love;Kerry P. Mahon;Christopher G. Levins;Kathryn A. Whitehead.
Proceedings of the National Academy of Sciences of the United States of America (2010)

721 Citations

Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates

Maria Frank-Kamenetsky;Aldo Grefhorst;Norma N. Anderson;Timothy S. Racie.
Proceedings of the National Academy of Sciences of the United States of America (2008)

671 Citations

Targeted delivery of RNAi therapeutics with endogenous and exogenous ligand-based mechanisms.

Akin Akinc;William Querbes;Soma De;June Qin.
Molecular Therapy (2010)

602 Citations

The α1β1 and α2β1 Integrins Provide Critical Support for Vascular Endothelial Growth Factor Signaling, Endothelial Cell Migration, and Tumor Angiogenesis

Donald R. Senger;Carole A. Perruzzi;Michael Streit;Victor E. Koteliansky.
American Journal of Pathology (2002)

434 Citations

Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death.

Vineet Bhandari;Rayman Choo-Wing;Chun G Lee;Zhou Zhu.
Nature Medicine (2006)

336 Citations

Delivery vehicles for small interfering RNA in vivo.

Antonin R. de Fougerolles.
Human Gene Therapy (2008)

322 Citations

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