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D-Index & Metrics

Immunology

D-Index
98
Citations
47971
World Ranking
776
National Ranking
50

Medicine

D-Index
99
Citations
48286
World Ranking
8446
National Ranking
479

Overview

Gunther Hartmann is primarily affiliated with the University Hospital Bonn in Germany. Their research spans several interconnected fields, most notably immunology, microbiology, biochemistry, genetics, molecular biology, and medicine.

Their work extensively covers subfields such as immunology, molecular biology, infectious diseases, cancer research, and oncology. The main topics addressed in their research include interferon and immune responses, immune response and inflammation, SARS-CoV-2 and COVID-19 research, extracellular vesicles in disease, inflammasome and immune disorders, COVID-19 clinical research studies, and immune cell function and interaction.

Frequent co-authors collaborating with Gunther Hartmann include Eva Bartok, Thomas Zillinger, Christoph Coch, Martin Schlee, and Beate M. Kümmerer.

Their research has been published prominently in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, The Journal of Experimental Medicine, Molecular Therapy - Nucleic Acids, and Scientific Reports.

Key recent papers by Gunther Hartmann and colleagues include:

  • Infection fatality rate of SARS-CoV2 in a super-spreading event in Germany (2020), Nature Communications
  • Infection fatality rate of SARS-CoV-2 infection in a German community with a super-spreading event (2020), bioRxiv (Cold Spring Harbor Laboratory)
  • Immune Sensing Mechanisms that Discriminate Self from Altered Self and Foreign Nucleic Acids (2020), Immunity
  • Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19 (2022), Nature
  • Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2 (2020), Immunity

Best Publications

  • A mammalian microRNA expression atlas based on small RNA library sequencing.

    Pablo Landgraf;Mirabela Rusu;Robert Sheridan;Alain Sewer;Alain Sewer

  • 5'-Triphosphate RNA Is the Ligand for RIG-I

    Veit Hornung;Jana Ellegast;Sarah Kim;Krzysztof Brzózka

  • Quantitative Expression of Toll-Like Receptor 1–10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides

    Veit Hornung;Simon Rothenfusser;Stefanie Britsch;Anne Krug

  • Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7.

    Veit Hornung;Margit Guenthner-Biller;Carole Bourquin;Andrea Ablasser

  • Identification of CpG oligonucleotide sequences with high induction of IFN‐α/β in plasmacytoid dendritic cells

    Anne Krug;Simon Rothenfusser;Veit Hornung;Bernd Jahrsdörfer

  • Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase

    Pu Gao;Manuel Ascano;Yang Wu;Winfried Barchet

  • Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence.

    Olaf Gross;Olaf Gross;Hendrik Poeck;Michael Bscheider;Catherine Dostert

  • RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate.

    Andrea Ablasser;Franz G. Bauernfeind;Gunther Hartmann;Eicke Latz

  • Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12.

    Anne Krug;Andreas Towarowski;Stefanie Britsch;Simon Rothenfusser

  • Recognition of 5′ Triphosphate by RIG-I Helicase Requires Short Blunt Double-Stranded RNA as Contained in Panhandle of Negative-Strand Virus

    Martin Schlee;Andreas Roth;Veit Hornung;Christina Amparo Hagmann

  • CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells.

    G. Hartmann;G. J. Weiner;A. M. Krieg

  • Mechanism and Function of a Newly Identified CpG DNA Motif in Human Primary B Cells

    Gunther Hartmann;Arthur M. Krieg;Arthur M. Krieg

  • Delineation of a CpG Phosphorothioate Oligodeoxynucleotide for Activating Primate Immune Responses In Vitro and In Vivo

    Gunther Hartmann;Risini D. Weeratna;Zuhair K. Ballas;Zuhair K. Ballas;Paul Payette

  • Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1|[beta]| production

    Hendrik Poeck;Michael Bscheider;Olaf Gross;Olaf Gross;Katrin Finger

  • Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates

    Delphine Goubau;Martin Schlee;Safia Deddouche;Andrea J. Pruijssers

  • Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA.

    Pu Gao;Manuel Ascano;Thomas Zillinger;Weiyi Wang

  • Discriminating self from non-self in nucleic acid sensing

    Martin Schlee;Gunther Hartmann

  • High altitude increases circulating interleukin-6, interleukin-1 receptor antagonist and C-reactive protein

    G. Hartmann;M. Tschöp;R. Fischer;C. Bidlingmaier

  • Plasmacytoid Dendritic Cells: A New Cutaneous Dendritic Cell Subset with Distinct Role in Inflammatory Skin Diseases

    Andreas Wollenberg;Moritz Wagner;Sandra Günther;Andreas Towarowski

  • Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon–independent apoptosis in human melanoma cells

    Robert Besch;Hendrik Poeck;Tobias Hohenauer;Daniela Senft

  • Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40L to induce high amounts of IL-12

    A. Towarowski;A. Krug;S. Britsch;S. Rothenfusser

Frequent Co-Authors

Stefan Endres
Stefan Endres Ludwig-Maximilians-Universität München
Veit Hornung
Veit Hornung Ludwig-Maximilians-Universität München
Winfried Barchet
Winfried Barchet University of Bonn
Arthur M. Krieg
Arthur M. Krieg University of Massachusetts Chan Medical School
Anne Krug
Anne Krug Ludwig-Maximilians-Universität München
Thomas Giese
Thomas Giese Heidelberg University
Dinshaw J. Patel
Dinshaw J. Patel Memorial Sloan Kettering Cancer Center
Thomas Tüting
Thomas Tüting Otto-von-Guericke University Magdeburg
Roger A. Jones
Roger A. Jones Rutgers, The State University of New Jersey
Thomas Tuschl
Thomas Tuschl Rockefeller University

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