Gunther Hartmann mainly investigates CpG site, Molecular biology, RNA, Immune system and Cell biology. His research integrates issues of In vitro, Plasmacytoid dendritic cell, CpG Oligodeoxynucleotide, Oligonucleotide and In vivo in his study of CpG site. His CpG Oligodeoxynucleotide research is multidisciplinary, relying on both Toll-Like Receptor 9 and CD86.
His work investigates the relationship between Molecular biology and topics such as TLR9 that intersect with problems in TLR2, T cell and Toll-like receptor. His work in RNA addresses issues such as Transcription, which are connected to fields such as MHC class II. His Immune system research includes elements of Gene silencing, DNA and Small interfering RNA.
His main research concerns Immunology, Immune system, Molecular biology, Cancer research and Cell biology. His work deals with themes such as Cytotoxic T cell and Receptor, which intersect with Immunology. His work carried out in the field of Molecular biology brings together such families of science as In vitro, RNA, CpG Oligodeoxynucleotide, Oligonucleotide and CpG site.
His CpG Oligodeoxynucleotide research integrates issues from Toll-Like Receptor 9 and B cell. His work focuses on many connections between CpG site and other disciplines, such as TLR9, that overlap with his field of interest in Plasmacytoid dendritic cell. Gunther Hartmann interconnects Inflammation and TLR3 in the investigation of issues within Cell biology.
His scientific interests lie mostly in Cancer research, Immune system, Cell biology, Internal medicine and Innate immune system. His study on Cancer research also encompasses disciplines like
His biological study spans a wide range of topics, including Intestinal mucosa, Cytokine, Secretion, Interleukin 21 and Proinflammatory cytokine. In Proinflammatory cytokine, Gunther Hartmann works on issues like Translational regulation, which are connected to CXCL10, Chemokine and Molecular biology. His Innate immune system research incorporates elements of Interferon, Melanoma and Immunity.
Immune system, Immunology, Nucleic acid, Innate immune system and Cell biology are his primary areas of study. The Immune system study combines topics in areas such as Kidney and Neuroblastoma. His Immunology study frequently draws parallels with other fields, such as Cancer research.
Gunther Hartmann has researched Nucleic acid in several fields, including Interferon, Immunity, TLR8, Receptor and Effector. His Innate immune system research includes elements of Acquired immune system, Secretion and CRISPR. He combines subjects such as Autophagy, Interleukin 21, Intestinal mucosa and Cytokine with his study of Cell biology.
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A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing
Pablo Landgraf;Mirabela Rusu;Robert Sheridan;Alain Sewer;Alain Sewer.
Cell (2007)
5'-Triphosphate RNA Is the Ligand for RIG-I
Veit Hornung;Jana Ellegast;Sarah Kim;Krzysztof Brzózka.
Science (2006)
Quantitative Expression of Toll-Like Receptor 1–10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides
Veit Hornung;Simon Rothenfusser;Stefanie Britsch;Anne Krug.
Journal of Immunology (2002)
Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7.
Veit Hornung;Margit Guenthner-Biller;Carole Bourquin;Andrea Ablasser.
Nature Medicine (2005)
Identification of CpG oligonucleotide sequences with high induction of IFN‐α/β in plasmacytoid dendritic cells
Anne Krug;Simon Rothenfusser;Veit Hornung;Bernd Jahrsdörfer.
European Journal of Immunology (2001)
Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12.
Anne Krug;Andreas Towarowski;Stefanie Britsch;Simon Rothenfusser.
European Journal of Immunology (2001)
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
Olaf Gross;Olaf Gross;Hendrik Poeck;Michael Bscheider;Catherine Dostert.
Nature (2009)
RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate.
Andrea Ablasser;Franz G. Bauernfeind;Gunther Hartmann;Eicke Latz.
Nature Immunology (2009)
CpG DNA : a potent signal for growth, activation, and maturation of human dendritic cells
G. Hartmann;G. J. Weiner;A. M. Krieg.
Proceedings of the National Academy of Sciences of the United States of America (1999)
Mechanism and Function of a Newly Identified CpG DNA Motif in Human Primary B Cells
Gunther Hartmann;Arthur M. Krieg;Arthur M. Krieg.
Journal of Immunology (2000)
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