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Jean-François Tanti

Jean-François Tanti

D-Index & Metrics

Molecular Biology

D-Index
52
Citations
21209
World Ranking
2406
National Ranking
91

Overview

Jean-François Tanti is affiliated with Université Côte d'Azur in France. Their research spans various fields, primarily focusing on Medicine and Biochemistry, Genetics and Molecular Biology. Within these areas, key subfields include Molecular Biology, Physiology, Epidemiology, Cancer Research, and Cardiology and Cardiovascular Medicine.

Their work addresses multiple main topics, such as:

  • Adipose Tissue and Metabolism
  • Adipokines, Inflammation, and Metabolic Diseases
  • Cardiovascular Disease and Adiposity
  • Metabolism, Diabetes, and Cancer
  • PI3K/AKT/mTOR signaling in cancer
  • MicroRNA in disease regulation
  • Prostate Cancer Treatment and Research

Selected recent papers include:

  • TAXOMET: A French Prospective Multicentric Randomized Phase II Study of Docetaxel Plus Metformin Versus Docetaxel Plus Placebo in Metastatic Castration-Resistant Prostate Cancer, 2021, Clinical Genitourinary Cancer
  • A Citrullus colocynthis fruit extract acutely enhances insulin-induced GLUT4 translocation and glucose uptake in adipocytes by increasing PKB phosphorylation, 2021, Journal of Ethnopharmacology
  • Inhibition of eIF5A hypusination reprogrammes metabolism and glucose handling in mouse kidney, 2021, Cell Death and Disease
  • REDD1 deficiency protects against nonalcoholic hepatic steatosis induced by high-fat diet, 2020, The FASEB Journal
  • Periprostatic Adipose Tissue Displays a Chronic Hypoxic State that Limits Its Expandability, 2022, American Journal Of Pathology

Frequent co-authors contributing to these research efforts include:

  • Mireille Cormont
  • Jérôme Gilleron
  • Jennifer Jager
  • David Estève
  • Catherine Muller

Their publications are often found in journals such as:

  • Journal of Visualized Experiments
  • American Journal Of Pathology
  • Cells
  • Clinical Genitourinary Cancer
  • Journal of Ethnopharmacology

Best Publications

  • Metabolic endotoxemia initiates obesity and insulin resistance

    Patrice D. Cani;Jacques Amar;Miguel Angel Iglesias;Marjorie Poggi

  • Positive and negative regulation of insulin signaling through IRS-1 phosphorylation

    Philippe Gual;Yannick Le Marchand-Brustel;Jean-François Tanti

  • The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level

    I Ben Sahra;K Laurent;K Laurent;A Loubat;A Loubat;S Giorgetti-Peraldi;S Giorgetti-Peraldi

  • Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression.

    Jennifer Jager;Thierry Grémeaux;Mireille Cormont;Yannick Le Marchand-Brustel

  • Metformin, Independent of AMPK, Induces mTOR Inhibition and Cell-Cycle Arrest through REDD1

    Isaam Ben Sahra;Claire Regazzetti;Guillaume Robert;Kathiane Laurent

  • Targeting Cancer Cell Metabolism: The Combination of Metformin and 2-Deoxyglucose Induces p53-Dependent Apoptosis in Prostate Cancer Cells

    Issam Ben Sahra;Kathiane Laurent;Sandy Giuliano;Frédéric Larbret

  • Metformin in cancer therapy: a new perspective for an old antidiabetic drug?

    Issam Ben Sahra;Yannick Le Marchand-Brustel;Jean François Tanti;Frédéric Bost

  • Cellular mechanisms of insulin resistance: role of stress-regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation.

    Jean-François Tanti;Jean-François Tanti;Jennifer Jager;Jennifer Jager

  • The lipid phosphatase SHIP2 controls insulin sensitivity

    Serge Clément;Ulrike Krause;Florence Desmedt;Jean-François Tanti

  • C3H/HeJ mice carrying a toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet

    M. Poggi;D. Bastelica;P. Gual;M. A. Iglesias

  • Serine/threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling.

    J F Tanti;T Grémeaux;E van Obberghen;Y Le Marchand-Brustel

  • Reduced Activation of Phosphatidylinositol-3 Kinase and Increased Serine 636 Phosphorylation of Insulin Receptor Substrate-1 in Primary Culture of Skeletal Muscle Cells From Patients With Type 2 Diabetes

    Karim Bouzakri;Marina Roques;Philippe Gual;Sophie Espinosa

  • Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy

    Valérie Risson;Laetitia Mazelin;Mila Roceri;Hervé Sanchez

  • Brain glucagon-like peptide–1 increases insulin secretion and muscle insulin resistance to favor hepatic glycogen storage

    Claude Knauf;Patrice D. Cani;Christophe Perrin;Miguel A. Iglesias

  • Potential role of protein kinase B in glucose transporter 4 translocation in adipocytes.

    J F Tanti;S Grillo;T Grémeaux;P J Coffer

  • Adipose Tissue MicroRNAs as Regulators of CCL2 Production in Human Obesity

    Erik Arner;Niklas Mejhert;Agné Kulyté;Piotr J. Balwierz

  • Hypoxia decreases insulin signaling pathways in adipocytes.

    Claire Regazzetti;Pascal Peraldi;Thierry Grémeaux;Rosanna Najem-Lendom

  • Implication of inflammatory signaling pathways in obesity-induced insulin resistance.

    Jean François Tanti;Jean François Tanti;Franck Ceppo;Franck Ceppo;Jennifer Jager;Jennifer Jager;Flavien Berthou;Flavien Berthou

  • Apelin and APJ regulation in adipose tissue and skeletal muscle of type 2 diabetic mice and humans

    Cédric Dray;Cyrille Debard;Jennifer Jager;Emmanuel Disse

  • Overexpression of a Constitutively Active Form of Phosphatidylinositol 3-Kinase Is Sufficient to Promote Glut 4 Translocation in Adipocytes

    Jean-François Tanti;Thierry Grémeaux;Sophie Grillo;Véronique Calleja

Frequent Co-Authors

Albert Tran
Albert Tran Inserm : Institut national de la santé et de la recherche médicale
Patrick Auberger
Patrick Auberger Grenoble Alpes University
Emmanuel Van Obberghen
Emmanuel Van Obberghen Université Côte d'Azur
Gilles Pagès
Gilles Pagès Sorbonne University
Hubert Vidal
Hubert Vidal Claude Bernard University Lyon 1
Jean-Ehrland Ricci
Jean-Ehrland Ricci Université Côte d'Azur
Jacques Pouysségur
Jacques Pouysségur Scientific Centre of Monaco
Emmanuel Lemichez
Emmanuel Lemichez Institut Pasteur

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