World's Best Scientists 2026 revealed!
Laurent Yvan-Charvet

Laurent Yvan-Charvet

D-Index & Metrics

Molecular Biology

D-Index
45
Citations
11279
World Ranking
2838
National Ranking
105

Overview

Laurent Yvan-Charvet is affiliated with Inserm in France and has a research focus intersecting medicine, immunology, and molecular biology. Their research output spans multiple domains within these fields, with significant contributions to the understanding of immune cells, metabolism, and lipid homeostasis.

The main fields of study associated with Laurent Yvan-Charvet include:

  • Medicine
  • Immunology and Microbiology
  • Biochemistry, Genetics and Molecular Biology

Subfields of study emphasize:

  • Immunology
  • Molecular Biology
  • Epidemiology
  • Physiology
  • Surgery

The scientist's research topics reflect a concentration on immunological processes and metabolic regulation, with key topics such as:

  • Immune cells in cancer
  • Immune Cell Function and Interaction
  • Phagocytosis and Immune Regulation
  • Adipokines, Inflammation, and Metabolic Diseases
  • Cholesterol and Lipid Metabolism
  • Immunotherapy and Immune Responses
  • Autophagy in Disease and Therapy

Laurent Yvan-Charvet's publication record includes work in journals and venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Nature Communications
  • Nature Metabolism
  • Immunity

Notable recent papers include:

  • Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis, 2020, Immunity
  • A subset of Kupffer cells regulates metabolism through the expression of CD36, 2021, Immunity
  • Single-cell analysis of human skin identifies CD14+ type 3 dendritic cells co-producing IL1B and IL23A in psoriasis, 2021, The Journal of Experimental Medicine
  • Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis, 2021, Cell Reports
  • Non-canonical glutamine transamination sustains efferocytosis by coupling redox buffering to oxidative phosphorylation, 2021, Nature Metabolism

Frequent collaborators with whom Laurent Yvan-Charvet has co-authored multiple publications include:

  • Emmanuel L. Gautier
  • Nathalie Vaillant
  • Thibault Barouillet
  • Stoyan Ivanov
  • Sébastien Dussaud

Best Publications

  • Cholesterol, inflammation and innate immunity

    Alan R. Tall;Laurent Yvan-Charvet

  • Cholesterol Efflux and Atheroprotection Advancing the Concept of Reverse Cholesterol Transport

    Robert S. Rosenson;H. Bryan Brewer;W. Sean Davidson;Zahi A. Fayad

  • ATP-Binding Cassette Transporters and HDL Suppress Hematopoietic Stem Cell Proliferation

    Laurent Yvan-Charvet;Tamara Pagler;Emmanuel L. Gautier;Serine Avagyan

  • Role of HDL, ABCA1, and ABCG1 Transporters in Cholesterol Efflux and Immune Responses

    Laurent Yvan-Charvet;Nan Wang;Alan R. Tall

  • Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice.

    Laurent Yvan-Charvet;Mollie Ranalletta;Nan Wang;Seongah Han

  • Increased Inflammatory Gene Expression in ABC Transporter-Deficient Macrophages: Free Cholesterol Accumulation, Increased Signaling via Toll-Like Receptors, and Neutrophil Infiltration of Atherosclerotic Lesions

    Laurent Yvan-Charvet;Carrie Welch;Tamara A. Pagler;Mollie Ranalletta

  • ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice

    Andrew J. Murphy;Mani Akhtari;Sonia Tolani;Tamara Pagler

  • Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis.

    Sophie Tran;Ines Baba;Lucie Poupel;Sébastien Dussaud

  • High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1.

    Naoki Terasaka;Nan Wang;Laurent Yvan-Charvet;Alan R. Tall

  • Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair

    Shuang Zhang;Samuel Weinberg;Matthew DeBerge;Anastasiia Gainullina

  • Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Macrophages Increases Inflammation and Accelerates Atherosclerosis in Mice

    Marit Westerterp;Andrew J. Murphy;Mi Wang;Tamara A. Pagler

  • Regulation of Hematopoietic Stem and Progenitor Cell Mobilization by Cholesterol Efflux Pathways

    Marit Westerterp;Samuel Gourion-Arsiquaud;Samuel Gourion-Arsiquaud;Andrew J. Murphy;Alan Shih

  • ATP-Binding Cassette Transporters, Atherosclerosis, and Inflammation

    Marit Westerterp;Andrea E. Bochem;Laurent Yvan-Charvet;Andrew J. Murphy

  • Role of adipose tissue renin-angiotensin system in metabolic and inflammatory diseases associated with obesity.

    Laurent Yvan-Charvet;Annie Quignard-Boulangé;Annie Quignard-Boulangé

  • Deletion of the angiotensin type 2 receptor (AT2R) reduces adipose cell size and protects from diet-induced obesity and insulin resistance.

    Laurent Yvan-Charvet;Patrick Even;May Bloch-Faure;Michèle Guerre-Millo

  • Inhibition of Cholesteryl Ester Transfer Protein by Torcetrapib Modestly Increases Macrophage Cholesterol Efflux to HDL

    Laurent Yvan-Charvet;Fumihiko Matsuura;Nan Wang;Mark J. Bamberger

  • ABCA1 and ABCG1 Protect Against Oxidative Stress-Induced Macrophage Apoptosis During Efferocytosis

    Laurent Yvan-Charvet;Tamara A. Pagler;Tracie A. Seimon;Edward Thorp

  • ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain

    Nan Wang;Laurent Yvan-Charvet;Dieter Lütjohann;Monique Mulder

  • Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis

    Andrew J Murphy;Nora Bijl;Laurent Yvan-Charvet;Carrie B Welch

  • Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity

    Marit Westerterp;Marit Westerterp;Emmanuel L. Gautier;Anjali Ganda;Matthew M. Molusky

Frequent Co-Authors

Alan R. Tall
Alan R. Tall Columbia University
Andrew J. Murphy
Andrew J. Murphy St. Jude Children's Research Hospital
Pascal Ferré
Pascal Ferré Sorbonne University
Ross L. Levine
Ross L. Levine Memorial Sloan Kettering Cancer Center
Jean-François Tanti
Jean-François Tanti Université Côte d'Azur
Naomi Taylor
Naomi Taylor National Institutes of Health
Benoit Malleret
Benoit Malleret National University of Singapore
Ilya Levental
Ilya Levental The University of Texas Health Science Center at Houston
Gwendalyn J. Randolph
Gwendalyn J. Randolph Washington University in St. Louis

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