World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
115
Citations
45034
World Ranking
4582
National Ranking
2488

Overview

Jay W. Heinecke is affiliated with the University of Washington in the United States. Their research spans multiple areas within medicine and biochemistry, with notable contributions to the study of diabetes, cardiovascular risks, and lipid metabolism.

The main fields of study for this scientist include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Their subfields of study focus on:

  • Endocrinology, Diabetes and Metabolism
  • Surgery
  • Molecular Biology
  • Cancer Research
  • Genetics

Jay W. Heinecke has conducted extensive research on topics including:

  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Cholesterol and Lipid Metabolism
  • Lipoproteins and Cardiovascular Health
  • Cancer, Lipids, and Metabolism
  • Diabetes Management and Research
  • Diabetes and associated disorders
  • Lipid metabolism and disorders

The scientist has published papers in several frequent publication venues such as:

  • Journal of Lipid Research
  • Circulation Research
  • Diabetes
  • Arteriosclerosis Thrombosis and Vascular Biology
  • Current Opinion in Lipidology

Selected recent publications include:

  • "Remnants of the Triglyceride-Rich Lipoproteins, Diabetes, and Cardiovascular Disease", 2020, Diabetes
  • "Diabetes Impairs Cellular Cholesterol Efflux From ABCA1 to Small HDL Particles", 2020, Circulation Research
  • "Helicobacter pylori outer membrane vesicles induce astrocyte reactivity through nuclear factor-κappa B activation and cause neuronal damage in vivo in a murine model", 2023, Journal of Neuroinflammation
  • "ABCA1 is an extracellular phospholipid translocase", 2022, Nature Communications
  • "Parallel Murine and Human Plaque Proteomics Reveals Pathways of Plaque Rupture", 2020, Circulation Research

Their frequent coauthors include:

  • Tomáš Vaisar
  • Karin Bornfeldt
  • W. Sean Davidson
  • Jere P. Segrest
  • Baohai Shao

Best Publications

  • The role of oxidized lipoproteins in atherogenesis

    Judith A. Berliner;Jay W. Heinecke

  • Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions.

    Alan Daugherty;Julie L. Dunn;Debra L. Rateri;Jay W. Heinecke

  • Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL

    Tomas Vaisar;Subramaniam Pennathur;Pattie S. Green;Sina A. Gharib

  • 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.

    Stanley L. Hazen;Jay W. Heinecke

  • Macrophage myeloperoxidase regulation by granulocyte macrophage colony-stimulating factor in human atherosclerosis and implications in acute coronary syndromes.

    Seigo Sugiyama;Yoshikatsu Okada;Galina K. Sukhova;Renu Virmani

  • Biomarkers of oxidative stress study II : are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning?

    M.B. Kadiiska;B.C. Gladen;D.D. Baird;D. Germolec

  • Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in culture.

    Jay W. Heinecke;Henry Rosen;Alan Chait

  • Superoxide-mediated modification of low density lipoprotein by arterial smooth muscle cells

    J W Heinecke;L Baker;H Rosen;A Chait

  • Dysfunctional HDL and atherosclerotic cardiovascular disease

    Robert S. Rosenson;H. Bryan Brewer;Benjamin J. Ansell;Philip Barter

  • ATP-Binding Cassette Transporter A1: A Cell Cholesterol Exporter That Protects Against Cardiovascular Disease

    John F. Oram;Jay W. Heinecke

  • The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells.

    J W Heinecke;H Rosen;L A Suzuki;A Chait

  • Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet

    Kelly A. Posey;Deborah J. Clegg;Richard L. Printz;Jaeman Byun

  • Oxidative Stress and Antioxidants in Exercise

    C. Leeuwenburgh;J. W. Heinecke

  • The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport

    Constanze Bergt;Subramaniam Pennathur;Xiaoyun Fu;Jaeman Byun

  • Long-Term Ascorbic Acid Administration Reverses Endothelial Vasomotor Dysfunction in Patients With Coronary Artery Disease

    Noyan Gokce;John F. Keaney;Balz Frei;Monika Holbrook

  • Reactive Nitrogen Intermediates Promote Low Density Lipoprotein Oxidation in Human Atherosclerotic Intima

    Christiaan Leeuwenburgh;Medora M. Hardy;Stanley L. Hazen;Peter Wagner

  • Increased atherosclerosis in myeloperoxidase-deficient mice

    Marie-Luise Brennan;Melissa M. Anderson;Diana M. Shih;Xiao-Dan Qu

  • Superoxide initiates oxidation of low density lipoprotein by human monocytes.

    K Hiramatsu;H Rosen;J W Heinecke;G Wolfbauer

  • MECHANISMS OF OXIDATIVE DAMAGE OF LOW DENSITY LIPOPROTEIN IN HUMAN ATHEROSCLEROSIS

    Jay W. Heinecke

  • Neuronal expression of myeloperoxidase is increased in Alzheimer's disease

    Pattie S. Green;Armando J. Mendez;Jason S. Jacob;Jan R. Crowley

Frequent Co-Authors

John F. Oram
John F. Oram University of Washington
Alan Chait
Alan Chait University of Washington
William C. Parks
William C. Parks Cedars-Sinai Medical Center
Kevin D. O'Brien
Kevin D. O'Brien University of Washington
W. Sean Davidson
W. Sean Davidson University of Cincinnati
Sina A. Gharib
Sina A. Gharib University of Washington
Jere P. Segrest
Jere P. Segrest Vanderbilt University
John D. Brunzell
John D. Brunzell University of Washington
Trevor J. Orchard
Trevor J. Orchard University of Pittsburgh
Bennett M. Shapiro
Bennett M. Shapiro VBL Therapeutics

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring medicine in the USA opens up a variety of alternative online pathways in the health field. For those without a nursing background, there are flexible direct entry online msn programs that allow you to earn a Master’s in Nursing and accelerate your nursing career. Similarly, online adn programs for non nurses provide a quicker entry point into nursing, often with less competitive admissions processes.

If you're interested in the administrative side of healthcare, consider programs at medical billing and coding schools with financial aid. These career-focused courses can provide a direct route to employment in hospitals or clinics, while also helping reduce education costs.

For students looking for less test-heavy options, some nursing school without teas test admissions are available, removing common entrance exam barriers. Exploring these online degrees can help you launch a rewarding healthcare career that best matches your interests, time, and educational background.

Best Scientists Citing Jay W. Heinecke

Trending Scientists

Recently Published Articles