David I. Pattison

Best Publications

• Absolute Rate Constants for the Reaction of Hypochlorous Acid with Protein Side Chains and Peptide Bonds

  David I. Pattison;Michael J. Davies

  885
  Citations

• Hypochlorite-induced oxidation of amino acids, peptides and proteins.

  C. L. Hawkins;D. I. Pattison;M. J. Davies

  693
  Citations

• Mammalian heme peroxidases: from molecular mechanisms to health implications.

  Michael J. Davies;Clare L. Hawkins;David I. Pattison;Martin D. Rees

  649
  Citations

• Photo-oxidation of proteins

  David I. Pattison;David I. Pattison;Aldwin Suryo Rahmanto;Michael J. Davies;Michael J. Davies

  611
  Citations

• Reactions of myeloperoxidase-derived oxidants with biological substrates: gaining chemical insight into human inflammatory diseases.

  D I Pattison;M J Davies

  407
  Citations

• Actions of ultraviolet light on cellular structures.

  David I. Pattison;Michael J. Davies

  397
  Citations

• Evidence for Rapid Inter- and Intramolecular Chlorine Transfer Reactions of Histamine and Carnosine Chloramines: Implications for the Prevention of Hypochlorous-Acid-Mediated Damage†

  David I Pattison;Michael J Davies

  350
  Citations

• Singlet-oxygen-mediated amino acid and protein oxidation: formation of tryptophan peroxides and decomposition products.

  Michelle Gracanin;Clare L. Hawkins;David I. Pattison;Michael J. Davies;Michael J. Davies

  286
  Citations

• Kinetic analysis of the reactions of hypobromous acid with protein components: implications for cellular damage and use of 3-bromotyrosine as a marker of oxidative stress.

  David I. Pattison;Michael J. Davies

  244
  Citations

• Reactions and reactivity of myeloperoxidase-derived oxidants: Differential biological effects of hypochlorous and hypothiocyanous acids

  David I Pattison;Michael J Davies;Clare L Hawkins

  200
  Citations

• Reevaluation of the rate constants for the reaction of hypochlorous acid (HOCl) with cysteine, methionine, and peptide derivatives using a new competition kinetic approach.

  Corin Storkey;Michael J. Davies;Michael J. Davies;David I. Pattison;David I. Pattison

  175
  Citations

• Reactivity of disulfide bonds is markedly affected by structure and environment: implications for protein modification and stability

  Maryam Karimi;Marta T. Ignasiak;Bun Chan;Anna K. Croft

  172
  Citations

• Hypochlorous Acid-Mediated Oxidation of Lipid Components and Antioxidants Present in Low-Density Lipoproteins: Absolute Rate Constants, Product Analysis, and Computational Modeling

  David I Pattison;Clare L Hawkins;Michael J Davies

  169
  Citations

• What Are the Plasma Targets of the Oxidant Hypochlorous Acid? A Kinetic Modeling Approach

  David I. Pattison;Clare L. Hawkins;Michael J. Davies

  145
  Citations

• Hypochlorous acid-mediated protein oxidation: how important are chloramine transfer reactions and protein tertiary structure?

  David I. Pattison;Clare L. Hawkins;Michael J. Davies

  143
  Citations

• Hypothiocyanous acid reactivity with low-molecular-mass and protein thiols: absolute rate constants and assessment of biological relevance

  Ojia Skaff;David I. Pattison;Michael J. Davies;Michael J. Davies

  139
  Citations

• Kinetic analysis of the role of histidine chloramines in hypochlorous acid mediated protein oxidation.

  David I Pattison;Michael J Davies

  123
  Citations

• Ability of hypochlorous acid and N-chloramines to chlorinate DNA and its constituents.

  Naomi R. Stanley;David I. Pattison;Clare L. Hawkins

  110
  Citations

• Oxidation of DNA, proteins and lipids by DOPA, protein-bound DOPA, and related catechol(amine)s.

  David I Pattison;Roger T Dean;Michael J Davies

  102
  Citations

• High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase.

  Philip E. Morgan;David I. Pattison;David I. Pattison;Jihan Talib;Fiona A. Summers

  99
  Citations