World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
11859
World Ranking
9868
National Ranking
264

Overview

Paul K. Witting is affiliated with the University of Sydney in Australia. Their research spans multiple fields within medicine and molecular biology, with a focus on immunology, genetics, pharmacology, and nutrition and dietetics. Their scholarly output covers significant topics such as neutrophil activity, inflammatory bowel disease, selenium in biological systems, medical and biological ozone research, amyloidosis, immune cells in cancer, and the roles of nitric oxide and endothelin effects.

They have contributed to a variety of publication venues, including:

  • International Journal of Molecular Sciences
  • Inflammatory Bowel Diseases
  • Free Radical Biology and Medicine
  • Scientific Reports
  • Antioxidants

Recent papers authored by Paul K. Witting include:

  • "Role for Selenium in Metabolic Homeostasis and Human Reproduction," 2021, published in Nutrients
  • "Neutrophil Extracellular Trap Density Increases With Increasing Histopathological Severity of Crohn's Disease," 2021, published in Inflammatory Bowel Diseases
  • "Physiological Benefits of Novel Selenium Delivery via Nanoparticles," 2023, published in International Journal of Molecular Sciences
  • "Neutrophil-Mediated Cardiac Damage After Acute Myocardial Infarction: Significance of Defining a New Target Cell Type for Developing Cardioprotective Drugs," 2020, published in Antioxidants and Redox Signaling
  • "Synthetic Cathinones Induce Cell Death in Dopaminergic SH-SY5Y Cells via Stimulating Mitochondrial Dysfunction," 2020, published in International Journal of Molecular Sciences

The scientist collaborates frequently with a number of coauthors, including:

  • Belal Chami
  • Yuyang Liu
  • Gulfam Ahmad
  • Angie L. Schroder
  • Tamara Ortíz

Their main fields of study include medicine and biochemistry, genetics and molecular biology. Subfields focus notably on immunology and molecular biology, which reflect the scientist's interest in immune mechanisms and cellular biology.

Paul K. Witting's research covers topics with a biomedical and molecular focus, especially related to inflammatory and oxidative mechanisms involving neutrophils, as well as the biological role of selenium and its delivery systems. Their work also engages with complex diseases such as inflammatory bowel disease and cardiac injury, indicating a broad engagement with pathophysiology in clinical and molecular contexts.

Best Publications

  • Kynurenine is an endothelium-derived relaxing factor produced during inflammation.

    Yutang Wang;Hanzhong Liu;Hanzhong Liu;Gavin McKenzie;Paul K. Witting

  • Redox Control of Endothelial Function and Dysfunction: Molecular Mechanisms and Therapeutic Opportunities

    Shane R Thomas;Paul K Witting;Grant Raymond Drummond

  • Oxidation of High Density Lipoproteins II. EVIDENCE FOR DIRECT REDUCTION OF LIPID HYDROPEROXIDES BY METHIONINE RESIDUES OF APOLIPOPROTEINS AI AND AII

    B Garner;A R Waldeck;P K Witting;K A Rye

  • Oxidation of High Density Lipoproteins I. FORMATION OF METHIONINE SULFOXIDE IN APOLIPOPROTEINS AI AND AII IS AN EARLY EVENT THAT ACCOMPANIES LIPID PEROXIDATION AND CAN BE ENHANCED BY α-TOCOPHEROL

    Brett Garner;Paul K. Witting;A. Reginald Waldeck;Julie K. Christison

  • Therapeutic Inflammatory Monocyte Modulation Using Immune-Modifying Microparticles

    Daniel R. Getts;Daniel R. Getts;Rachael L. Terry;Rachael L. Terry;Meghann Teague Getts;Celine Deffrasnes

  • The Peroxidase Activity of a Hemin−DNA Oligonucleotide Complex: Free Radical Damage to Specific Guanine Bases of the DNA†

    P Travascio;P K Witting;A G Mauk;D Sen

  • α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II

    Lan-Feng Dong;Pauline Low;Jeffrey C. Dyason;Xiu-Fang Wang

  • Protective Role for Antioxidants in Acute Kidney Disease

    Joanne M. Dennis;Paul K. Witting

  • Myeloperoxidase in the inflamed colon: A novel target for treating inflammatory bowel disease.

    Belal Chami;Nathan J.J. Martin;Joanne M. Dennis;Paul K. Witting

  • Mitochondrial Targeting of Vitamin E Succinate Enhances Its Pro-apoptotic and Anti-cancer Activity via Mitochondrial Complex II

    Lan-feng Dong;Victoria J. A. Jameson;David Patrice Tilly;Jiri Cerny

  • Mitochondria play a central role in apoptosis induced by α-Tocopheryl succinate, an agent with antineoplastic activity: Comparison with receptor-mediated pro-apoptotic signaling

    Tobias Weber;Helge Dalen;Ladislav Andera;Anne Nègre-Salvayre

  • Antioxidants protect from atherosclerosis by a heme oxygenase-1 pathway that is independent of free radical scavenging

    Ben J. Wu;Krishna Kathir;Paul K. Witting;Konstanze Beck

  • Serum amyloid A induction of cytokines in monocytes/macrophages and lymphocytes

    Changjie Song;Kenneth Hsu;Eric Yamen;Weixing Yan

  • Evidence That Niacin Inhibits Acute Vascular Inflammation and Improves Endothelial Dysfunction Independent of Changes in Plasma Lipids

    Ben J. Wu;Ling Yan;Francesca Charlton;Paul Witting

  • α-Tocopheryl Succinate Inhibits Malignant Mesothelioma by Disrupting the Fibroblast Growth Factor Autocrine Loop MECHANISM AND THE ROLE OF OXIDATIVE STRESS

    Michael Stapelberg;Nina Gellert;Emma Swettenham;Marco Tomasetti

  • Dissociation of atherogenesis from aortic accumulation of lipid hydro(pero)xides in Watanabe heritable hyperlipidemic rabbits

    Paul Witting;Knut Pettersson;Ann-Margret Östlund-Lindqvist;Christer Westerlund

  • Probucol Protects Against Smooth Muscle Cell Proliferation by Upregulating Heme Oxygenase-1

    Yi-Mo Deng;Ben J. Wu;Paul K. Witting;Roland Stocker

  • Oxidants and antioxidants in atherosclerosis.

    Ryuichi Mashima;Paul K. Witting;Roland Stocker

  • Vitamin E Analogues Inhibit Angiogenesis by Selective Induction of Apoptosis in Proliferating Endothelial Cells: The Role of Oxidative Stress

    Lan-Feng Dong;Emma Swettenham;Johanna Eliasson;Xiu-Fang Wang

  • Suppression of Tumor Growth In vivo by the Mitocan α-tocopheryl Succinate Requires Respiratory Complex II

    Lan-feng Dong;Ruth Freeman;Ji Liu;Renata Zobalova

Frequent Co-Authors

Roland Stocker
Roland Stocker The Heart Research Institute
Jiri Neuzil
Jiri Neuzil Czech Academy of Sciences
Hugh H. Harris
Hugh H. Harris University of Adelaide
Peter A. Lay
Peter A. Lay University of Sydney
Carolyn L. Geczy
Carolyn L. Geczy University of New South Wales
David S. Celermajer
David S. Celermajer Royal Prince Alfred Hospital
Stefan Vogt
Stefan Vogt Argonne National Laboratory
Michael J. Davies
Michael J. Davies University of Copenhagen
Stephen John Ralph
Stephen John Ralph Griffith University
A. Grant Mauk
A. Grant Mauk University of British Columbia

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