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Biology and Biochemistry
UK
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
156
Citations
93899
World Ranking
142
National Ranking
8

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2025 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2023 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2022 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2012 - Fellow of the Royal Society of New Zealand

Overview

Michael P. Murphy is affiliated with the University of Cambridge in the United Kingdom. The primary focus of their research lies in Medicine and Biochemistry, Genetics, and Molecular Biology, encompassing a broad range of subfields including Molecular Biology, Physiology, Immunology, Pathology and Forensic Medicine, and Cardiology and Cardiovascular Medicine.

Their research explores several key topics, notably Mitochondrial Function and Pathology, Cardiac Ischemia and Reperfusion, Adipose Tissue and Metabolism, ATP Synthase and ATPases Research, Cardiovascular Function and Risk Factors, Immune cells in cancer, and Birth, Development, and Health.

Michael P. Murphy has contributed to multiple publications, with selected recent papers including:

  • Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo (2022), published in Nature Metabolism
  • Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology (2022), published in Nature Reviews Molecular Cell Biology
  • Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing (2020), published in Nature Reviews Drug Discovery
  • Cholangiocyte organoids can repair bile ducts after transplantation in the human liver (2021), published in Science
  • Macrophage metabolic reprogramming presents a therapeutic target in lupus nephritis (2020), published in Proceedings of the National Academy of Sciences

Frequent co-authors collaborating with Michael P. Murphy include:

  • Hiran A. Prag
  • Thomas Krieg
  • Richard C. Hartley
  • Andrew M. James
  • Christian Frezza

Their work has been frequently published in venues such as bioRxiv (Cold Spring Harbor Laboratory), Free Radical Biology and Medicine, Redox Biology, Nature Communications, and Nature.

Michael P. Murphy has been recognized as a Fellow of the Royal Society of New Zealand, an award received in 2012.

Best Publications

  • How mitochondria produce reactive oxygen species.

    Michael P. Murphy

  • Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.

    Edward T. Chouchani;Edward T. Chouchani;Victoria R. Pell;Edoardo Gaude;Dunja Aksentijević

  • Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

    Evanna L. Mills;Beth Kelly;Angela Logan;Ana S.H. Costa

  • Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.

    Evanna L Mills;Dylan G Ryan;Hiran A Prag;Dina Dikovskaya

  • Targeting Antioxidants to Mitochondria by Conjugation to Lipophilic Cations

    Michael P. Murphy;Robin A.J. Smith

  • Selective Targeting of a Redox-active Ubiquinone to Mitochondria within Cells: ANTIOXIDANT AND ANTIAPOPTOTIC PROPERTIES *

    Geoffrey F. Kelso;Carolyn M. Porteous;Carolyn V. Coulter;Gillian Hughes

  • Unraveling the biological roles of reactive oxygen species.

    Michael P. Murphy;Arne Holmgren;Nils Göran Larsson;Barry Halliwell

  • Selective fluorescent imaging of superoxide in vivo using ethidium-based probes

    Kristine M. Robinson;Michael S. Janes;Mariana Pehar;Jeffrey S. Monette

  • Delivery of bioactive molecules to mitochondria in vivo

    Robin A. J. Smith;Carolyn M. Porteous;Alison M. Gane;Michael P. Murphy

  • Redox Homeostasis and Mitochondrial Dynamics.

    Peter H.G.M. Willems;Rodrigue Rossignol;Cindy E.J. Dieteren;Michael P. Murphy

  • COVID-19 vaccine coverage in health-care workers in England and effectiveness of BNT162b2 mRNA vaccine against infection (SIREN): a prospective, multicentre, cohort study.

    Victoria Jane Hall;Victoria Jane Hall;Sarah Foulkes;Ayoub Saei;Nick Andrews;Nick Andrews

  • Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes.

    Katherine Green;Martin D. Brand;Michael P. Murphy

  • Targeting an antioxidant to mitochondria decreases cardiac ischemia-reperfusion injury

    Victoria J. Adlam;Joanne C. Harrison;Carolyn M. Porteous;Andrew M. James

  • Animal and human studies with the mitochondria-targeted antioxidant MitoQ.

    Robin A.J. Smith;Michael P. Murphy

  • The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production

    Eric L. Bell;Tatyana A. Klimova;James Eisenbart;Carlos T. Moraes

  • IgH class switching and translocations use a robust non-classical end-joining pathway

    Catherine T. Yan;Cristian Boboila;Ellen Kris Souza;Sonia Franco

  • Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I

    Edward T Chouchani;Carmen Methner;Sergiy M Nadtochiy;Angela Logan

  • Complex I Is the Major Site of Mitochondrial Superoxide Production by Paraquat

    Helena M. Cochemé;Michael P. Murphy

  • A Unifying Mechanism for Mitochondrial Superoxide Production during Ischemia-Reperfusion Injury.

    Edward T. Chouchani;Victoria R. Pell;Andrew M. James;Lorraine M. Work

  • Targeting Antioxidants to Mitochondria by Conjugation to Lipophilic

    Michael P. Murphy;Robin A. J. Smith

Frequent Co-Authors

Robin A. J. Smith
Robin A. J. Smith University of Otago
Andrew M. James
Andrew M. James MRC Mitochondrial Biology Unit
Thomas Krieg
Thomas Krieg University of Cambridge
Christian Frezza
Christian Frezza University of Cambridge
Luke A. J. O'Neill
Luke A. J. O'Neill Trinity College Dublin
Martin D. Brand
Martin D. Brand Buck Institute for Research on Aging
Ian M. Fearnley
Ian M. Fearnley University of Cambridge
Linda Partridge
Linda Partridge Max Planck Society
Aleksandra Filipovska
Aleksandra Filipovska University of Western Australia
Martin R. Bennett
Martin R. Bennett University of Cambridge

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