D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 52 Citations 9,866 157 World Ranking 12051 National Ranking 293

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Mitochondrion

Werner J.H. Koopman mainly focuses on Mitochondrion, Cell biology, Oxidative phosphorylation, Reactive oxygen species and Biochemistry. His Mitochondrion research focuses on Cell and how it relates to Reactive nitrogen species. His Cell biology study combines topics from a wide range of disciplines, such as PINK1 and Membrane potential.

His studies examine the connections between Membrane potential and genetics, as well as such issues in Rhodamine, with regards to Calcium and Mitochondrial matrix. His work deals with themes such as Carcinogenesis, Leigh disease, Melanoma and Small molecule, which intersect with Oxidative phosphorylation. His studies deal with areas such as Oxidative stress, Cell signaling and Homeostasis as well as Reactive oxygen species.

His most cited work include:

  • Monogenic Mitochondrial Disorders (348 citations)
  • Mammalian Mitochondrial Complex I: Biogenesis, Regulation, and Reactive Oxygen Species Generation (292 citations)
  • Mitochondrial function and morphology are impaired in parkin mutant fibroblasts (272 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Mitochondrion, Cell biology, Oxidative phosphorylation, Biochemistry and Cell. The concepts of his Mitochondrion study are interwoven with issues in Endocrinology, Reactive oxygen species, Internal medicine, Membrane potential and Mitochondrial disease. His research in Cell biology intersects with topics in Mitochondrial matrix and Cytosol.

His Oxidative phosphorylation research integrates issues from Oxidoreductase, Inner mitochondrial membrane, Mitochondrial DNA, Molecular biology and Fibroblast. His work on Antioxidant, Enzyme and ATP synthase as part of general Biochemistry research is often related to Trolox, thus linking different fields of science. His Cell study combines topics in areas such as Cell culture, Transfection, Signal transduction and Microscopy.

He most often published in these fields:

  • Mitochondrion (50.63%)
  • Cell biology (42.41%)
  • Oxidative phosphorylation (26.58%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cell biology (42.41%)
  • Mitochondrion (50.63%)
  • Cell (20.89%)

In recent papers he was focusing on the following fields of study:

Werner J.H. Koopman spends much of his time researching Cell biology, Mitochondrion, Cell, Biochemistry and Biophysics. His Cell biology study frequently links to other fields, such as Oxidative stress. Werner J.H. Koopman has included themes like Bioinformatics, NDUFS4, Mitochondrial disease, Function and Wild type in his Mitochondrion study.

His biological study spans a wide range of topics, including Oxidative phosphorylation, Computational biology and Orphan drug. His Cell course of study focuses on Cell culture and Citrate synthase. His study in the fields of Membrane potential under the domain of Biophysics overlaps with other disciplines such as Rhodamine 123 and Astrocyte.

Between 2015 and 2021, his most popular works were:

  • Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells. (110 citations)
  • Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells. (71 citations)
  • Mitochondrial disorders in children: toward development of small-molecule treatment strategies (61 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Werner J.H. Koopman mostly deals with Mitochondrion, Cell biology, Function, Oxidative phosphorylation and Cytosol. Werner J.H. Koopman has researched Mitochondrion in several fields, including Cell, Protein kinase A and Bioinformatics. His Cell biology research is multidisciplinary, incorporating perspectives in Ferroptosis, Electron transport chain, Melanoma and Necroptosis.

His work carried out in the field of Function brings together such families of science as Nanoreactor and Synthetic Organelles. The study incorporates disciplines such as Carcinogenesis, Coenzyme Q – cytochrome c reductase, Alternative oxidase and Dihydroorotate dehydrogenase in addition to Oxidative phosphorylation. His Cytosol research is multidisciplinary, relying on both Oxidative stress, Extracellular, MPTP, Mitochondrial permeability transition pore and Cyclosporin a.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Redox Homeostasis and Mitochondrial Dynamics.

Peter H.G.M. Willems;Rodrigue Rossignol;Cindy E.J. Dieteren;Michael P. Murphy.
Cell Metabolism (2015)

546 Citations

Monogenic Mitochondrial Disorders

Werner J H Koopman;Peter H G M Willems;Jan A M Smeitink.
The New England Journal of Medicine (2012)

520 Citations

Mammalian Mitochondrial Complex I: Biogenesis, Regulation, and Reactive Oxygen Species Generation

Werner J.H. Koopman;Leo G.J. Nijtmans;Cindy E.J. Dieteren;Peggy Roestenberg.
Antioxidants & Redox Signaling (2010)

435 Citations

Mitochondrial function and morphology are impaired in parkin mutant fibroblasts

Heather Mortiboys;Kelly Jean Thomas;Werner J. H. Koopman;Stefanie Klaffke.
Annals of Neurology (2008)

398 Citations

Mitochondrial complex I deficiency: from organelle dysfunction to clinical disease

Felix Distelmaier;Felix Distelmaier;Werner J.H. Koopman;Lambertus P. van den Heuvel;Richard J. Rodenburg.
Brain (2008)

345 Citations

Inhibition of complex I of the electron transport chain causes O2−·-mediated mitochondrial outgrowth

Werner J. H. Koopman;Sjoerd Verkaart;Henk-Jan Visch;Francois H. van der Westhuizen.
American Journal of Physiology-cell Physiology (2005)

297 Citations

An anaerobic mitochondrion that produces hydrogen

Brigitte Boxma;Rob M. de Graaf;Georg W.M. van der Staay;Theo A. van Alen.
Nature (2005)

277 Citations

OXPHOS mutations and neurodegeneration

Werner J H Koopman;Felix Distelmaier;Jan A M Smeitink;Peter H G M Willems.
The EMBO Journal (2012)

256 Citations

Interactions between mitochondrial reactive oxygen species and cellular glucose metabolism

Dania C. Liemburg-Apers;Peter H. G. M. Willems;Werner J. H. Koopman;Sander Grefte;Sander Grefte.
Archives of Toxicology (2015)

220 Citations

Mitochondrial network complexity and pathological decrease in complex I activity are tightly correlated in isolated human complex I deficiency

Werner J. H. Koopman;Henk-Jan Visch;Sjoerd Verkaart;Lambertus W. P. J. van den Heuvel.
American Journal of Physiology-cell Physiology (2005)

218 Citations

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