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Massimo Zeviani

Massimo Zeviani

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Genetics
Italy
2026
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Genetics and Molecular Biology
Italy
2024

D-Index & Metrics

Genetics

D-Index
133
Citations
62538
World Ranking
234
National Ranking
1

Medicine

D-Index
133
Citations
63063
World Ranking
2239
National Ranking
47

Research.com Recognitions

  • 2026 - Research.com Genetics in Italy Leader Award
  • 2025 - Research.com Genetics in Italy Leader Award
  • 2024 - Research.com Genetics in Italy Leader Award
  • 2024 - Research.com Genetics and Molecular Biology in Italy Leader Award
  • 2023 - Research.com Genetics in Italy Leader Award
  • 2023 - Research.com Genetics and Molecular Biology in Italy Leader Award
  • 2022 - Research.com Genetics and Molecular Biology in Italy Leader Award
  • 2013 - Grand Prix scientifique de la Fondation NRJ, Institut de France

Overview

Massimo Zeviani is affiliated with the University of Padua in Italy and has contributed extensively to the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology, Clinical Biochemistry, Cellular and Molecular Neuroscience, Genetics, and Physiology. Their research centers primarily on mitochondrial function and pathology, ATP synthase and ATPases research, and the intersection of metabolism with genetic disorders.

Their recent influential papers include:

  • Mitochondrial disorders of the OXPHOS system, 2020, published in FEBS Letters
  • Neural stem cells traffic functional mitochondria via extracellular vesicles, 2021, published in PLoS Biology
  • Mitochondrial Structure and Bioenergetics in Normal and Disease Conditions, 2021, published in International Journal of Molecular Sciences
  • Respiratory supercomplexes act as a platform for complex III -mediated maturation of human mitochondrial complexes I and IV, 2020, published in The EMBO Journal
  • Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer's disease-like pathology in human cerebral organoids, 2020, published in Molecular Psychiatry

Zeviani frequently collaborates with other researchers in the field, with notable co-authors including Carlo Viscomi, Erika Fernández-Vizarra, Michele Brischigliaro, Raffaele Cerutti, and Shujing Ding. Their publication record reflects strong engagement with several scientific venues, notably bioRxiv (Cold Spring Harbor Laboratory), Biochimica et Biophysica Acta (BBA) - Bioenergetics, International Journal of Molecular Sciences, Cells, and Neurology Genetics.

Their research topics demonstrate a diverse engagement in:

  • Mitochondrial Function and Pathology
  • ATP Synthase and ATPases Research
  • Metabolism and Genetic Disorders
  • Photosynthetic Processes and Mechanisms
  • RNA modifications and cancer
  • Genetic Neurodegenerative Diseases
  • RNA and protein synthesis mechanisms

Zeviani has been recognized with the Grand Prix scientifique de la Fondation NRJ awarded by Institut de France in 2013.

Best Publications

  • Identification and characterization of a spinal muscular atrophy-determining gene

    Suzie Lefebvre;Lydie Bürglen;Sophie Reboullet;Olivier Clermont

  • Mitochondrial DNA Deletions in Progressive External Ophthalmoplegia and Kearns-Sayre Syndrome

    Carlos T. Moraes;Salvatore Dimauro;Massimo Zeviani;Anne Lombes

  • Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria.

    Johannes N. Spelbrink;Fang Yuan Li;Valeria Tiranti;Kaisu Nikali

  • Spastic Paraplegia and OXPHOS Impairment Caused by Mutations in Paraplegin, a Nuclear-Encoded Mitochondrial Metalloprotease

    Giorgio Casari;Maurizio De Fusco;Sonia Ciarmatori;Massimo Zeviani

  • Deletions of mitochondrial DNA in Kearns‐Sayre syndrome

    M. Zeviani;C. T. Moraes;S. DiMauro;H. Nakase

  • Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation

    Joslyn K. Brunelle;Eric L. Bell;Nancy M. Quesada;Kristel Vercauteren

  • An autosomal dominant disorder with multiple deletions of mitochondrial DNA starting at the D-loop region.

    Massimo Zeviani;Serenella Servidei;Cinzia Gellera;Enrico Bertini

  • Role of Adenine Nucleotide Translocator 1 in mtDNA Maintenance

    Jyrki Kaukonen;Jukka K. Juselius;Valeria Tiranti;Aija Kyttälä

  • A direct repeat is a hotspot for large-scale deletion of human mitochondrial DNA

    Eric A. Schon;Rosario Rizzuto;Carlos T. Moraes;Hirofumi Nakase

  • Familial Progressive Sensorineural Deafness Is Mainly Due to the mtDNA A1555G Mutation and Is Enhanced by Treatment with Aminoglycosides

    Xavier Estivill;Nancy Govea;Anna Barceló;Enric Perelló

  • Mutations of SURF-1 in Leigh Disease Associated with Cytochrome c Oxidase Deficiency

    Valeria Tiranti;Konstanze Hoertnagel;Rosalba Carrozzo;Claudia Galimberti

  • The Molecular Dissection of mtDNA Haplogroup H Confirms That the Franco-Cantabrian Glacial Refuge Was a Major Source for the European Gene Pool

    Alessandro Achilli;Chiara Rengo;Chiara Magri;Vincenza Battaglia

  • Mitochondrial disorders

    Massimo Zeviani;Antonella Spinazzola

  • Multi-system neurological disease is common in patients with OPA1 mutations

    Patrick Yu-Wai-Man;Philip G. Griffiths;Philip G. Griffiths;G. Gorman;C.-M. Lourenco

  • MPV17 encodes an inner mitochondrial membrane protein and is mutated in infantile hepatic mitochondrial DNA depletion

    Antonella Spinazzola;Carlo Viscomi;Erika Fernandez-Vizarra;Franco Carrara

  • Systematic identification of human mitochondrial disease genes through integrative genomics.

    Sarah Calvo;Mohit Jain;Mohit Jain;Xiaohui Xie;Sunil A Sheth;Sunil A Sheth

  • Maternally inherited myopathy and cardiomyopathy: association with mutation in mitochondrial DNA tRNALeu(UUR)

    M. Zeviani;C. Gellera;C. Antozzi;M. Rimoldi

  • Cytochrome C oxidase deficiency in Leigh syndrome

    Salvatore DiMauro;Serenella Servidei;Massimo Zeviani;Maja DiRocco

  • Haplotype and phylogenetic analyses suggest that one European-specific mtDNA background plays a role in the expression of Leber hereditary optic neuropathy by increasing the penetrance of the primary mutations 11778 and 14484

    A Torroni;M Petrozzi;L D'Urbano;D Sellitto

  • The Opa1-Dependent Mitochondrial Cristae Remodeling Pathway Controls Atrophic, Apoptotic, and Ischemic Tissue Damage

    Tatiana Varanita;Maria Eugenia Soriano;Vanina Romanello;Tania Zaglia

Frequent Co-Authors

Valeria Tiranti
Valeria Tiranti Istituto Neurologico Carlo Besta
Eleonora Lamantea
Eleonora Lamantea Istituto Neurologico Carlo Besta
Daniele Ghezzi
Daniele Ghezzi University of Milan
Valerio Carelli
Valerio Carelli University of Bologna
Salvatore DiMauro
Salvatore DiMauro Columbia University
Graziella Uziel
Graziella Uziel Istituto Neurologico Carlo Besta
Patrick F. Chinnery
Patrick F. Chinnery University of Cambridge
Enrico Bertini
Enrico Bertini Bambino Gesù Children's Hospital
Giacomo P. Comi
Giacomo P. Comi University of Milan
Holger Prokisch
Holger Prokisch Technical University of Munich

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