What is he best known for?
The fields of study he is best known for:
- Gene
- Internal medicine
- Mutation
Genetics, Mitochondrial DNA, Mitochondrial optic neuropathies, Optic neuropathy and Mitochondrion are his primary areas of study.
His work carried out in the field of Mitochondrial DNA brings together such families of science as Molecular biology and Peninsula.
His Optic neuropathy study combines topics in areas such as Nerve fiber layer, Retina and Retinal ganglion.
His research in Mitochondrion intersects with topics in Internal medicine, Endocrinology, Programmed cell death and Mitochondrial disease.
The Leber's hereditary optic neuropathy study combines topics in areas such as Idebenone and Mitochondrial biogenesis.
His Optic nerve research includes themes of Atrophy and Pathology.
His most cited work include:
- Mitochondrial dysfunction as a cause of optic neuropathies (555 citations)
- The Molecular Dissection of mtDNA Haplogroup H Confirms That the Franco-Cantabrian Glacial Refuge Was a Major Source for the European Gene Pool (400 citations)
- Haplotype and phylogenetic analyses suggest that one European-specific mtDNA background plays a role in the expression of Leber hereditary optic neuropathy by increasing the penetrance of the primary mutations 11778 and 14484. (396 citations)
What are the main themes of his work throughout his whole career to date?
Valerio Carelli mainly investigates Leber's hereditary optic neuropathy, Genetics, Mitochondrial DNA, Optic neuropathy and Pathology.
His Leber's hereditary optic neuropathy study introduces a deeper knowledge of Ophthalmology.
His research related to Penetrance, Gene, Heteroplasmy, Haplotype and Haplogroup might be considered part of Genetics.
His study in Mitochondrial DNA is interdisciplinary in nature, drawing from both Mutation, Point mutation, Molecular biology and Mitochondrion.
His Mitochondrion research is multidisciplinary, incorporating perspectives in mitochondrial fusion, Oxidative phosphorylation and ATP synthase.
His Optic neuropathy study combines topics from a wide range of disciplines, such as Retina, Retinal ganglion, Mitochondrial optic neuropathies and Idebenone.
He most often published in these fields:
- Leber's hereditary optic neuropathy (31.19%)
- Genetics (28.92%)
- Mitochondrial DNA (28.92%)
What were the highlights of his more recent work (between 2016-2021)?
- Mitochondrial DNA (28.92%)
- Genetics (28.92%)
- Ophthalmology (17.96%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Mitochondrial DNA, Genetics, Ophthalmology, Atrophy and Leber's hereditary optic neuropathy.
His research integrates issues of Phenotype, Mitochondrion and Gene isoform in his study of Mitochondrial DNA.
Valerio Carelli works mostly in the field of Atrophy, limiting it down to topics relating to Optic nerve and, in certain cases, Neurology, as a part of the same area of interest.
His Leber's hereditary optic neuropathy research is under the purview of Optic neuropathy.
Valerio Carelli has included themes like Visual system, Mitochondrial optic neuropathies and Melanopsin, Retinal ganglion in his Optic neuropathy study.
His Mutation research is multidisciplinary, incorporating elements of Ataxia and Molecular biology.
Between 2016 and 2021, his most popular works were:
- The glutamate/cystine xCT antiporter antagonizes glutamine metabolism and reduces nutrient flexibility. (87 citations)
- OPA1 Isoforms in the Hierarchical Organization of Mitochondrial Functions (77 citations)
- Mitochondrial DNA and primary mitochondrial dysfunction in Parkinson's disease (77 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- Mutation
His primary areas of investigation include Mitochondrial DNA, Genetics, Leber's hereditary optic neuropathy, Optic nerve and Neuroscience.
Valerio Carelli combines subjects such as Phenotype, GTPase, Cell biology and Gene isoform with his study of Mitochondrial DNA.
Optic neuropathy and Ophthalmology are the focus of his Leber's hereditary optic neuropathy studies.
In his study, which falls under the umbrella issue of Optic nerve, Mitochondrial DNA replication is strongly linked to Atrophy.
The study incorporates disciplines such as Mitochondrial optic neuropathies, Neurodegeneration and Parkinson's disease in addition to Retinal ganglion.
The various areas that Valerio Carelli examines in his Mitochondrial myopathy study include Hereditary Optic Atrophy, Mutation, Molecular biology, Mitochondrion and Transplantation.
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