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Biology and Biochemistry

D-Index
58
Citations
10988
World Ranking
13285
National Ranking
53

Overview

Sérgio Simões is affiliated with the University of Coimbra in Portugal. Their research spans fields such as Medicine and Biochemistry, Genetics and Molecular Biology. Within these broader categories, their work focuses on subfields including Molecular Biology, Pharmaceutical Science, Immunology, Oncology, and Biomaterials.

The scientist's research topics cover various specialized areas including Drug Solubility and Delivery Systems, Biosimilars and Bioanalytical Methods, Computational Drug Discovery Methods, RNA Interference and Gene Delivery, Advanced Biosensing and Bioanalysis Techniques, Advanced Polymer Synthesis and Characterization, and Biodegradable Polymer Synthesis and Properties.

Coauthors who frequently collaborate with Sérgio Simões include João Nuno Moreira, Nuno A. Fonseca, Ana Sofia Lourenço, Vera Moura, and Marta F. Simões.

They have contributed to publications predominantly in the following journals:

  • International Journal of Pharmaceutics
  • European Journal of Pharmaceutics and Biopharmaceutics
  • Journal of Drug Delivery Science and Technology
  • Journal of Controlled Release
  • Cancers

Recent papers authored or coauthored by Sérgio Simões include:

  • Bacterial vaginosis: Standard treatments and alternative strategies (2020), International Journal of Pharmaceutics
  • Artificial neural networks applied to quality-by-design: From formulation development to clinical outcome (2020), European Journal of Pharmaceutics and Biopharmaceutics
  • A quality by design (QbD) approach in pharmaceutical development of lipid-based nanosystems: A systematic review (2022), Journal of Drug Delivery Science and Technology
  • Quality by design (QbD) approach in marketing authorization procedures of Non-Biological Complex Drugs: A critical evaluation (2022), European Journal of Pharmaceutics and Biopharmaceutics
  • Amphiphilic well-defined degradable star block copolymers by combination of ring-opening polymerization and atom transfer radical polymerization: Synthesis and application as drug delivery carriers (2021), Journal of Polymer Science

Best Publications

  • Paclitaxel-loaded PLGA nanoparticles: preparation, physicochemical characterization and in vitro anti-tumoral activity

    Cristina Fonseca;Sérgio Simões;Rogério Gaspar

  • On the formulation of pH-sensitive liposomes with long circulation times

    Sérgio Simões;João Nuno Moreira;Cristina Fonseca;Nejat Düzgüneş

  • Cationic lipid-DNA complexes in gene delivery: from biophysics to biological applications.

    Maria C Pedroso de Lima;Sérgio Simões;Pedro Pires;Henrique Faneca

  • Oral films: Current status and future perspectives: I - Galenical development and quality attributes.

    Ana Filipa Borges;Cláudia Silva;Jorge F.J. Coelho;Sérgio Simões

  • Cationic liposomes for gene delivery.

    Sérgio Simões;Ana Filipe;Henrique Faneca;Miguel Mano

  • Sterically Stabilized pH-sensitive Liposomes INTRACELLULAR DELIVERY OF AQUEOUS CONTENTS AND PROLONGED CIRCULATION IN VIVO

    Vladimir A. Slepushkin;Sérgio Simões;Paul Dazin;Mary S. Newman

  • Lipid-based nanoparticles for siRNA delivery in cancer therapy: paradigms and challenges.

    Lígia C. Gomes-da-Silva;Nuno A. Fonseca;Vera Moura;Maria C. Pedroso de Lima

  • Gene delivery by negatively charged ternary complexes of DNA, cationic liposomes and transferrin or fusigenic peptides

    S Simões;S Simões;V Slepushkin;R Gaspar;MC Pedroso de Lima

  • Mechanisms of singlet-oxygen and superoxide-ion generation by porphyrins and bacteriochlorins and their implications in photodynamic therapy.

    Elsa F. F. Silva;Carlos Serpa;Janusz M. Dąbrowski;Carlos J. P. Monteiro

  • Mechanisms of gene transfer mediated by lipoplexes associated with targeting ligands or pH-sensitive peptides

    S Simões;V Slepushkin;P Pires;P Pires;R Gaspar

  • On the mechanisms of internalization and intracellular delivery mediated by pH-sensitive liposomes

    Sérgio Simões;Vladimir Slepushkin;Nejat Düzgünes;Maria C. Pedroso de Lima

  • Human serum albumin enhances DNA transfection by lipoplexes and confers resistance to inhibition by serum

    Sérgio Simões;Sérgio Simões;Vladimir Slepushkin;Pedro Pires;Rogério Gaspar

  • Cationic Liposomes for Gene Delivery: From Biophysics to Biological Applications

    M. C. Pedroso de Lima;S. Neves;A. Filipe;N. Duzgunes

  • Interaction of cationic liposomes and their DNA complexes with monocytic leukemia cells.

    Pedro Pires;Sérgio Simões;Shlomo Nir;Rogério Gaspar

  • Steric stabilization of nanoparticles: Size and surface properties

    Cristina Lourenco;Maribel Teixeira;Sérgio Simões;Rogério Gaspar

  • Quality by design in pharmaceutical manufacturing: A systematic review of current status, challenges and future perspectives.

    Helena Bigares Grangeia;Cláudia Silva;Sérgio Paulo Simões;Marco S. Reis

  • Improving chitosan-mediated gene transfer by the introduction of intracellular buffering moieties into the chitosan backbone.

    C. Moreira;H. Oliveira;L.R. Pires;S. Simões

  • Gene delivery mediated by cationic liposomes: from biophysical aspects to enhancement of transfection.

    Maria C. Pedroso;de Lima;Sergio Simoes;Pedro Pires

  • New halogenated water-soluble chlorin and bacteriochlorin as photostable PDT sensitizers: synthesis, spectroscopy, photophysics, and in vitro photosensitizing efficacy.

    Janusz M. Dąbrowski;Luis G. Arnaut;Mariette M. Pereira;Carlos J. P. Monteiro

  • Improving lipoplex-mediated gene transfer into C6 glioma cells and primary neurons.

    M.Teresa Girão da Cruz;Sérgio Simões;Maria C. Pedroso de Lima

Frequent Co-Authors

Nejat Düzgüneş
Nejat Düzgüneş University of the Pacific
Jorge F. J. Coelho
Jorge F. J. Coelho University of Coimbra
Mariette M. Pereira
Mariette M. Pereira University of Coimbra
Luís Pereira de Almeida
Luís Pereira de Almeida University of Coimbra
Björn Lindman
Björn Lindman Lund University
Vitaly Citovsky
Vitaly Citovsky Stony Brook University
Ernst Wagner
Ernst Wagner Ludwig-Maximilians-Universität München
John J. Rossi
John J. Rossi City Of Hope National Medical Center
Carsten Culmsee
Carsten Culmsee Philipp University of Marburg
Mário A. Barbosa
Mário A. Barbosa University of Porto

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