What is she best known for?
The fields of study she is best known for:
Her scientific interests lie mostly in Neuroscience, Neurotrophic factors, Huntington's disease, Huntingtin and Striatum.
Her research in Neurotrophic factors is mostly focused on Glial cell line-derived neurotrophic factor.
Her studies deal with areas such as Glutamate receptor, Biochemistry, Ciliary neurotrophic factor and Genetic enhancement as well as Huntington's disease.
Her Huntingtin research incorporates elements of Molecular biology, Cancer research and Neurodegeneration.
Her Neurodegeneration study integrates concerns from other disciplines, such as Genetics, Gene silencing and RNA interference.
Her Striatum research is multidisciplinary, incorporating perspectives in Pharmacology and Pathology.
Her most cited work include:
- Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease. (1142 citations)
- α-Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease (446 citations)
- Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients. (410 citations)
What are the main themes of her work throughout her whole career to date?
Her primary areas of investigation include Huntingtin, Cell biology, Neuroscience, Huntington's disease and Molecular biology.
Her studies in Huntingtin integrate themes in fields like Striatum and Neurodegeneration.
Her Cell biology research includes themes of Programmed cell death, Astrocyte and Biochemistry.
The Neuroscience study combines topics in areas such as Glial cell line-derived neurotrophic factor, Neurotrophic factors and Viral vector.
Her study in Huntington's disease is interdisciplinary in nature, drawing from both Neurotoxicity, Endocrinology and Neuroprotection.
Her Molecular biology research includes elements of Cell culture, Gene expression, Transgene, NeuN and RNA interference.
She most often published in these fields:
- Huntingtin (44.72%)
- Cell biology (35.77%)
- Neuroscience (34.96%)
What were the highlights of her more recent work (between 2014-2021)?
- Huntingtin (44.72%)
- Neuroscience (34.96%)
- Cell biology (35.77%)
In recent papers she was focusing on the following fields of study:
Her main research concerns Huntingtin, Neuroscience, Cell biology, Huntington's disease and Viral vector.
Her Huntingtin research is multidisciplinary, relying on both Gene silencing and Striatum.
Her study in the field of Astrocyte, Dopamine and Hippocampal formation also crosses realms of Prefrontal cortex.
The various areas that Nicole Déglon examines in her Cell biology study include Small hairpin RNA, Downregulation and upregulation and Gene isoform.
Her research investigates the connection between Huntington's disease and topics such as Endocrinology that intersect with issues in Neuron.
Her Viral vector study combines topics in areas such as Cell culture, Cell type and Induced pluripotent stem cell.
Between 2014 and 2021, her most popular works were:
- The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer's and Huntington's diseases. (126 citations)
- The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer's and Huntington's diseases. (126 citations)
- The Self-Inactivating KamiCas9 System for the Editing of CNS Disease Genes (54 citations)
In her most recent research, the most cited papers focused on:
Nicole Déglon mostly deals with Cell biology, Huntingtin, Neuroscience, Gene and Huntington's disease.
Her research integrates issues of Small hairpin RNA, Gene silencing and microRNA in her study of Cell biology.
Her work deals with themes such as Endocrinology and Energy homeostasis, which intersect with Huntingtin.
Nicole Déglon has included themes like Gene expression and Janus kinase in her Neuroscience study.
Her Huntington's disease research is multidisciplinary, incorporating perspectives in AMP-activated protein kinase, AMPK, Neuron, Activator and Programmed cell death.
Her Mutant study combines topics in areas such as Non-coding RNA, Cancer research, Neurodegeneration, RNA interference and Genetic enhancement.
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