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Neuroscience
Switzerland
2026

D-Index & Metrics

Neuroscience

D-Index
111
Citations
37061
World Ranking
530
National Ranking
10

Research.com Recognitions

  • 2026 - Research.com Neuroscience in Switzerland Leader Award
  • 2025 - Research.com Neuroscience in Switzerland Leader Award
  • 2013 - Fellow, National Academy of Inventors
  • 2001 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Patrick Aebischer is affiliated with the École Polytechnique Fédérale de Lausanne in Switzerland. Their research spans several interconnected fields, primarily focusing on Medicine, Nursing, and Biochemistry, Genetics and Molecular Biology. Within these broader domains, key subfields of their work include Nutrition and Dietetics, Biochemistry, Neurology, Genetics, and Molecular Biology.

The scientist's research addresses multiple topics, with an emphasis on the following areas:

  • Pomegranate: compositions and health benefits
  • Antioxidant Activity and Oxidative Stress
  • Amyotrophic Lateral Sclerosis Research
  • Neurogenetic and Muscular Disorders Research
  • Muscle Physiology and Disorders
  • Paraoxonase enzyme and polymorphisms
  • Nutrition and Health in Aging

Among recent scholarly publications, the following papers illustrate the scope and focus of Aebischer's work:

  • Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults, 2022, Cell Reports Medicine
  • Effect of Urolithin A Supplementation on Muscle Endurance and Mitochondrial Health in Older Adults, 2022, JAMA Network Open
  • Direct supplementation with Urolithin A overcomes limitations of dietary exposure and gut microbiome variability in healthy adults to achieve consistent levels across the population, 2021, European Journal of Clinical Nutrition
  • Astrocyte-targeting RNA interference against mutated superoxide dismutase 1 induces motoneuron plasticity and protects fast-fatigable motor units in a mouse model of amyotrophic lateral sclerosis, 2022, Glia
  • Expression of a miRNA targeting mutated SOD1 in astrocytes induces motoneuron plasticity and improves neuromuscular function in ALS mice, 2021, bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors collaborating with Patrick Aebischer include:

  • Anurag Singh
  • Davide D'Amico
  • Chris Rinsch
  • Pénélope A. Andreux
  • William Blanco-Bose

The scientist's publications appear in several notable journals and venues, such as:

  • Cell Reports Medicine
  • JAMA Network Open
  • European Journal of Clinical Nutrition
  • Glia
  • bioRxiv (Cold Spring Harbor Laboratory)

Patrick Aebischer has received recognition including:

  • Fellow, National Academy of Inventors (2013)
  • Fellow of the Indian National Academy of Engineering (INAE) (2001)

Best Publications

  • Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease.

    Jeffrey H. Kordower;Marina E. Emborg;Jocelyne Bloch;Shuang Y. Ma

  • Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents

    Dongryeol Ryu;Laurent Mouchiroud;Pénélope A Andreux;Elena Katsyuba

  • Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS

    Cédric Raoul;Toufik Abbas-Terki;Jean-Charles Bensadoun;Sandrine Guillot

  • α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer.

    Bruno Fauvet;Martial Kamdem Mbefo;Mohamed-Bilal Fares;Carole Desobry

  • α-Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease

    C. Lo Bianco;J. L. Ridet;B. L. Schneider;N. Deglon

  • A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord.

    Xiao Ming Xu;Véronique Guénard;Naomi Kleitman;Patrick Aebischer

  • In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons

    Philipp Mächler;Matthias T. Wyss;Maha Elsayed;Jillian Stobart

  • Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients.

    Patrick Aebischer;Myriam Schluep;Nicole Déglon;Jean-Marc Joseph

  • A versatile tool for conditional gene expression and knockdown

    Jolanta Szulc;Maciej Wiznerowicz;Maciej Wiznerowicz;Marc-Olivier Sauvain;Marc-Olivier Sauvain;Didier Trono;Didier Trono

  • Syngeneic Schwann cells derived from adult nerves seeded in semipermeable guidance channels enhance peripheral nerve regeneration

    Unknown

  • Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions.

    Yaping Chu;Hemraj Dodiya;Patrick Aebischer;C. Warren Olanow

  • Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an α-synuclein rat model of Parkinson's disease

    Christophe Lo Bianco;Bernard L. Schneider;Matthias Bauer;Ali Sajadi

  • Lentiviral-Mediated RNA Interference

    Toufik Abbas-Terki;William Blanco-Bose;Nicole Déglon;William Pralong

  • Isolation of multipotent neural precursors residing in the cortex of the adult human brain.

    Yvan Arsenijevic;Jean-Guy Villemure;Jean-François Brunet;Jocelyne J. Bloch

  • Enzymatic incorporation of bioactive peptides into fibrin matrices enhances neurite extension.

    Jason C. Schense;Jason C. Schense;Jocelyne Bloch;Patrick Aebischer;Jeffrey A. Hubbell

  • GDNF and NGF released by synthetic guidance channels support sciatic nerve regeneration across a long gap.

    Eric G. Fine;Isabelle Decosterd;Michael Papaloïzos;Anne D. Zurn

  • Phosphorylation at S87 Is Enhanced in Synucleinopathies, Inhibits α-Synuclein Oligomerization, and Influences Synuclein-Membrane Interactions

    Katerina E. Paleologou;Abid Oueslati;Gideon Shakked;Carla C. Rospigliosi

  • GDNF secreting human neural progenitor cells protect dying motor neurons, but not their projection to muscle, in a rat model of familial ALS.

    Masatoshi Suzuki;Jacalyn McHugh;Craig Tork;Brandon Shelley

  • Insulin-Like Growth Factor-I Is Necessary for Neural Stem Cell Proliferation and Demonstrates Distinct Actions of Epidermal Growth Factor and Fibroblast Growth Factor-2

    Yvan Arsenijevic;Samuel Weiss;Bernard Schneider;Patrick Aebischer

  • Self-Inactivating Lentiviral Vectors with Enhanced Transgene Expression as Potential Gene Transfer System in Parkinson's Disease

    N. Déglon;J. L. Tseng;J.C. Bensadoun;A. D. Zurn

  • Regrowth of axons into the distal spinal cord through a Schwann-cell-seeded mini-channel implanted into hemisected adult rat spinal cord.

    Xiao Ming Xu;Shu-Xin Zhang;Huaying Li;Patrick Aebischer

  • GDNF delivery using human neural progenitor cells in a rat model of ALS.

    Sandra M. Klein;Soshana Behrstock;Jacalyn McHugh;Kristin Hoffmann

Frequent Co-Authors

Jocelyne Bloch
Jocelyne Bloch University of Lausanne
Jeffrey H. Kordower
Jeffrey H. Kordower Arizona State University
Isabelle Decosterd
Isabelle Decosterd University of Lausanne
Emmanuel Brouillet
Emmanuel Brouillet Centre national de la recherche scientifique, CNRS
Yaping Chu
Yaping Chu Rush University Medical Center
Xiao Ming Xu
Xiao Ming Xu Indiana University
Christopher E. Henderson
Christopher E. Henderson Biogen (United States)
James W. Fawcett
James W. Fawcett University of Cambridge
Pierre J. Magistretti
Pierre J. Magistretti École Polytechnique Fédérale de Lausanne
Maciej Wiznerowicz
Maciej Wiznerowicz Poznan University of Medical Sciences

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