Christian Becker

Overview

Best Publications

• Comprehensive genomic profiles of small cell lung cancer

  Julie George;Jing Shan Lim;Se Jin Jang;Yupeng Cun

  2106
  Citations

• Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

  Martin Peifer;Lynnette Fernández-Cuesta;Martin L. Sos;Julie George

  1542
  Citations

• Lifestyle transitions in plant pathogenic Colletotrichum fungi deciphered by genome and transcriptome analyses

  Richard J. O'Connell;Michael R. Thon;Stéphane Hacquard;Stefan G. Amyotte

  1118
  Citations

• The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4

  John A. Sayer;John A. Sayer;Edgar A. Otto;John F. O'Toole;Gudrun Nurnberg

  764
  Citations

• Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible.

  Bernward Hinkes;Roger C. Wiggins;Rasheed Gbadegesin;Christopher N. Vlangos

  647
  Citations

• Correlation between genetic and geographic structure in Europe.

  Oscar Lao;Timothy T. Lu;Michael Nothnagel;Olaf Junge

  595
  Citations

• Diagnostic yield of various genetic approaches in patients with unexplained developmental delay or mental retardation.

  Anita Rauch;Juliane Hoyer;Sabine Guth;Christiane Zweier

  550
  Citations

• Mutations in the Tight-Junction Gene Claudin 19 (CLDN19) Are Associated with Renal Magnesium Wasting, Renal Failure, and Severe Ocular Involvement

  Martin Konrad;André Schaller;Dominik Seelow;Amit V. Pandey

  533
  Citations

• Familial hemophagocytic lymphohistiocytosis type 5 (FHL-5) is caused by mutations in Munc18-2 and impaired binding to syntaxin 11.

  Udo zur Stadt;Jan Rohr;Wenke Seifert;Wenke Seifert;Florian Koch

  483
  Citations

• Mutations in MRAP, encoding a new interacting partner of the ACTH receptor, cause familial glucocorticoid deficiency type 2.

  Louise A Metherell;J Paul Chapple;Sadani Cooray;Alessia David

  458
  Citations

• Mutations in STRA6 cause a broad spectrum of malformations including anophthalmia, congenital heart defects, diaphragmatic hernia, alveolar capillary dysplasia, lung hypoplasia, and mental retardation

  Francesca Pasutto;Heinrich Sticht;Gerhard Hammersen;Gabriele Gillessen-Kaesbach

  456
  Citations

• COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness

  Saskia F. Heeringa;Gil Chernin;Moumita Chaki;Weibin Zhou

  442
  Citations

• A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease

  Stephan Buch;Clemens Schafmayer;Henry Völzke;Christian Becker

  396
  Citations

• Loss of Nephrocystin-3 Function Can Cause Embryonic Lethality, Meckel-Gruber-like Syndrome, Situs Inversus, and Renal-Hepatic-Pancreatic Dysplasia

  Carsten Bergmann;Manfred Fliegauf;Nadina Ortiz Brüchle;Valeska Frank

  379
  Citations

• Integrative genomic profiling of large-cell neuroendocrine carcinomas reveals distinct subtypes of high-grade neuroendocrine lung tumors

  Julie George;Vonn Walter;Vonn Walter;Martin Peifer;Ludmil B. Alexandrov

  305
  Citations

• NSUN4 Is a Dual Function Mitochondrial Protein Required for Both Methylation of 12S rRNA and Coordination of Mitoribosomal Assembly

  Metodi Dimitrov Metodiev;Henrik Spahr;Paola Loguercio Polosa;Caroline Meharg

  282
  Citations

• CD74-NRG1 fusions in lung adenocarcinoma

  Lynnette Fernandez-Cuesta;Dennis Plenker;Hirotaka Osada;Ruping Sun

  275
  Citations

• Mutations in RDH12 encoding a photoreceptor cell retinol dehydrogenase cause childhood-onset severe retinal dystrophy

  Andreas R Janecke;Debra A Thompson;Gerd Utermann;Christian Becker

  274
  Citations

• tRNA splicing endonuclease mutations cause pontocerebellar hypoplasia.

  Birgit S. Budde;Yasmin Namavar;Peter G. Barth;Bwee Tien Poll-The

  265
  Citations

• Loss of GLIS2 causes nephronophthisis in humans and mice by increased apoptosis and fibrosis

  Massimo Attanasio;N. Henriette Uhlenhaut;Vitor H. Sousa;John F. O'Toole

  263
  Citations