World's Best Scientists 2026 revealed!
Takeshi Imamura

Takeshi Imamura

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Biology and Biochemistry
Japan
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
101
Citations
37949
World Ranking
1440
National Ranking
82

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Takeshi Imamura is affiliated with Ehime University in Japan and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research spans various subfields including molecular biology, surgery, biophysics, biomedical engineering, and immunology.

The scientist's work covers a range of topics, prominently featuring advanced fluorescence microscopy techniques, hip disorders and treatments, bone health and osteoporosis research, cancer cells and metastasis, optical coherence tomography applications, cancer immunotherapy and biomarkers, as well as orthopaedic implants and arthroplasty.

Notable recent publications include:

  • Cell-matrix interface regulates dormancy in human colon cancer stem cells, 2022, Nature
  • Wide field light-sheet microscopy with lens-axicon controlled two-photon Bessel beam illumination, 2021, Nature Communications
  • Profiling the inhibitory receptors LAG-3, TIM-3, and TIGIT in renal cell carcinoma reveals malignancy, 2021, Nature Communications
  • A novel negative regulatory mechanism of Smurf2 in BMP/Smad signaling in bone, 2020, Bone Research
  • Identification of Quiescent LGR5+ Stem Cells in the Human Colon, 2022, Gastroenterology

Frequent co-authors collaborating with Takeshi Imamura include:

  • Ryosuke Kawakami
  • Yosuke Niko
  • Masamoto Murakami
  • Teruko Tsuda
  • Takashi Saitou

Imamura has published multiple papers in prominent venues such as:

  • Proceedings for Annual Meeting of The Japanese Pharmacological Society
  • Scientific Reports
  • Advanced Functional Materials
  • Nature Communications
  • Chemical Science

Best Publications

  • Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression

    Asako Sakaue-Sawano;Hiroshi Kurokawa;Toshifumi Morimura;Aki Hanyu

  • Smad6 inhibits signalling by the TGF-Beta superfamily

    Takeshi Imamura;Masao Takase;Ayako Nishihara;Eiichi Oeda

  • TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4.

    Atsuhito Nakao;Takeshi Imamura;Takeshi Imamura;Serhiy Souchelnytskyi;Masahiro Kawabata

  • Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation.

    Takanori Ebisawa;Minoru Fukuchi;Gyo Murakami;Tomoki Chiba

  • BMP receptor signaling: Transcriptional targets, regulation of signals, and signaling cross-talk

    Kohei Miyazono;Kohei Miyazono;Shingo Maeda;Takeshi Imamura

  • Activin receptor-like kinase 1 modulates transforming growth factor-β1 signaling in the regulation of angiogenesis

    S. Paul Oh;Tsugio Seki;Kendrick A. Goss;Takeshi Imamura

  • Signal transduction by bone morphogenetic proteins.

    Masahiro Kawabata;Takeshi Imamura;Kohei Miyazono

  • Cloning and characterization of a human type II receptor for bone morphogenetic proteins

    B L Rosenzweig;T Imamura;T Okadome;G N Cox

  • Roles of Bone Morphogenetic Protein Type I Receptors and Smad Proteins in Osteoblast and Chondroblast Differentiation

    M Fujii;K Takeda;T Imamura;H Aoki

  • Interaction and Functional Cooperation of PEBP2/CBF with Smads SYNERGISTIC INDUCTION OF THE IMMUNOGLOBULIN GERMLINE Cα PROMOTER

    Jun Ichi Hanai;Lin Feng Chen;Tomohiko Kanno;Naoko Ohtani-Fujita

  • SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes

    Takeshi Yoshizaki;Jill C. Milne;Takeshi Imamura;Simon Schenk

  • The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-beta.

    Masayoshi Tojo;Masayoshi Tojo;Yoshio Hamashima;Aki Hanyu;Tetsuya Kajimoto

  • Endogenous TGF-β signaling suppresses maturation of osteoblastic mesenchymal cells

    Shingo Maeda;Shingo Maeda;Makoto Hayashi;Setsuro Komiya;Takeshi Imamura

  • Characterization of bone morphogenetic protein-6 signaling pathways in osteoblast differentiation.

    T. Ebisawa;K. Tada;I. Kitajima;K. Tojo

  • Cooperative Inhibition of Bone Morphogenetic Protein Signaling by Smurf1 and Inhibitory Smads

    Gyo Murakami;Tetsuro Watabe;Kunio Takaoka;Kohei Miyazono

  • Negative regulation of BMP/Smad signaling by Tob in osteoblasts.

    Yutaka Yoshida;Sakae Tanaka;Hisashi Umemori;Osamu Minowa

  • Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors.

    Masahiro Kawabata;Hirofumi Inoue;Aki Hanyu;Takeshi Imamura

  • Distinct and Overlapping Patterns of Localization of Bone Morphogenetic Protein (BMP) Family Members and a BMP Type II Receptor During Fracture Healing in Rats

    T Onishi;Y Ishidou;T Nagamine;K Yone

  • Glypican-3, overexpressed in hepatocellular carcinoma, modulates FGF2 and BMP-7 signaling.

    Yutaka Midorikawa;Shumpei Ishikawa;Hiroko Iwanari;Takeshi Imamura

  • Regulation of TGF‐β family signaling by E3 ubiquitin ligases

    Yasumichi Inoue;Takeshi Imamura

Frequent Co-Authors

Kohei Miyazono
Kohei Miyazono University of Tokyo
Keiji Miyazawa
Keiji Miyazawa University of Yamanashi
Masahiro Kawabata
Masahiro Kawabata Japanese Foundation For Cancer Research
Hiroyuki Aburatani
Hiroyuki Aburatani University of Tokyo
Peter ten Dijke
Peter ten Dijke Leiden University Medical Center
Tetsuro Watabe
Tetsuro Watabe Tokyo Medical and Dental University
Carl-Henrik Heldin
Carl-Henrik Heldin Uppsala University
Keiji Tanaka
Keiji Tanaka Tokyo Metropolitan Institute of Medical Science
Tomoki Chiba
Tomoki Chiba University of Tsukuba

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