2022 - Research.com Biology and Biochemistry in Netherlands Leader Award
Member of the European Molecular Biology Organization (EMBO)
Peter ten Dijke mostly deals with SMAD, Signal transduction, Cancer research, Cell biology and Transforming growth factor. His SMAD research is multidisciplinary, relying on both R-SMAD, Transcription factor and Hedgehog signaling pathway. His Signal transduction research is multidisciplinary, incorporating elements of Receptor, Phosphorylation and Gefitinib.
His work deals with themes such as Epithelial–mesenchymal transition, Metastasis and Immunology, which intersect with Cancer research. His Cell biology study combines topics from a wide range of disciplines, such as Cellular differentiation, Internal medicine, Bone morphogenetic protein and Endocrinology. The Transforming growth factor study combines topics in areas such as Cancer and Transforming growth factor, beta 3.
His primary scientific interests are in Cell biology, Cancer research, Transforming growth factor, SMAD and Signal transduction. His Cell biology study integrates concerns from other disciplines, such as Receptor, Endocrinology and Bone morphogenetic protein. Peter ten Dijke has included themes like Cancer cell, Cancer, Breast cancer, Metastasis and Transforming growth factor beta in his Cancer research study.
His biological study spans a wide range of topics, including Fibrosis, Extracellular matrix, Transforming growth factor, beta 3 and Cell growth. His work in SMAD tackles topics such as Molecular biology which are related to areas like TGF beta receptor 2. His Signal transduction study incorporates themes from Epithelial–mesenchymal transition, Ubiquitin, Mesenchymal stem cell and Immunology.
Peter ten Dijke focuses on Cancer research, Cell biology, Transforming growth factor, Signal transduction and SMAD. His Cancer research research is multidisciplinary, incorporating elements of Bladder cancer, Cancer, Metastasis, Cancer cell and Transforming growth factor beta. The various areas that Peter ten Dijke examines in his Cell biology study include In vitro, Ubiquitin and Bone morphogenetic protein.
His studies in Transforming growth factor integrate themes in fields like Slug, Regulation of gene expression and Transcription factor. The Signal transduction study combines topics in areas such as Cell, Tissue homeostasis and Mesoderm. He studied SMAD and Crosstalk that intersect with Neuroscience.
His primary areas of study are Cancer research, Signal transduction, Metastasis, Transforming growth factor and Cancer cell. His work deals with themes such as Carcinogenesis, Transforming growth factor beta, Downregulation and upregulation and Bone morphogenetic protein, which intersect with Cancer research. His Signal transduction research is classified as research in Cell biology.
His Cell biology research incorporates themes from Tissue engineering and Angiogenesis. His research investigates the connection between Transforming growth factor and topics such as Cancer that intersect with problems in Immune system, Immunogenicity, Immunology and Blockade. His biological study spans a wide range of topics, including Glycolysis and TGF beta signaling pathway.
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TGF-beta signalling from cell membrane to nucleus through SMAD proteins
Carl-Henrik Heldin;Kohei Miyazono;Peter ten Dijke.
Nature (1997)
TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4.
Atsuhito Nakao;Takeshi Imamura;Takeshi Imamura;Serhiy Souchelnytskyi;Masahiro Kawabata.
The EMBO Journal (1997)
TGF-β in progression of liver disease
Steven Dooley;Peter ten Dijke.
Cell and Tissue Research (2012)
Signaling inputs converge on nuclear effectors in TGF-β signaling
Peter ten Dijke;Kohei Miyazono;Carl-Henrik Heldin.
Trends in Biochemical Sciences (2000)
Phosphorylation of Ser465 and Ser467 in the C Terminus of Smad2 Mediates Interaction with Smad4 and Is Required for Transforming Growth Factor-β Signaling
Serhiy Souchelnytskyi;Kiyoshi Tamaki;Ulla Engström;Christer Wernstedt.
Journal of Biological Chemistry (1997)
INDUCTION OF INHIBITORY SMAD6 AND SMAD7 MRNA BY TGF-BETA FAMILY MEMBERS
Mozhgan Afrakhte;Anita Morén;Surinder Jossan;Susumu Itoh.
Biochemical and Biophysical Research Communications (1998)
Signaling by members of the TGF-β family in vascular morphogenesis and disease
Evangelia Pardali;Marie-José Goumans;Peter ten Dijke.
Trends in Cell Biology (2010)
The dynamic roles of TGF‐β in cancer
Erik Meulmeester;Peter ten Dijke;Peter ten Dijke.
The Journal of Pathology (2011)
MED12 Controls the Response to Multiple Cancer Drugs through Regulation of TGF-β Receptor Signaling.
Sidong Huang;Michael Hölzel;Theo Knijnenburg;Andreas Schlicker.
Cell (2012)
The Tumor Suppressor Smad4 Is Required for Transforming Growth Factor β–Induced Epithelial to Mesenchymal Transition and Bone Metastasis of Breast Cancer Cells
Martine Deckers;Maarten van Dinther;Jeroen Buijs;Ivo Que.
Cancer Research (2006)
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