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Biology and Biochemistry
Netherlands
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
150
Citations
82417
World Ranking
180
National Ranking
1

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Netherlands Leader Award
  • 2025 - Research.com Biology and Biochemistry in Netherlands Leader Award
  • 2023 - Research.com Biology and Biochemistry in Netherlands Leader Award
  • 2022 - Research.com Biology and Biochemistry in Netherlands Leader Award
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Peter ten Dijke is affiliated with Leiden University Medical Center in the Netherlands. Their research output spans primarily the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions to Medicine.

The main subfields of their publications include Molecular Biology, Oncology, Immunology, Cell Biology, and Cancer Research. The predominant topics covered in their work are TGF-β signaling in diseases, Cancer Cells and Metastasis, Ubiquitin and proteasome pathways, Immune cells in cancer, Pancreatic and Hepatic Oncology Research, Liver physiology and pathology, and Extracellular vesicles in disease.

Peter ten Dijke's recent papers showcase a focus on cellular signaling, cancer biology, and immune system interactions. These publications include:

  • Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches, 2022, Cell
  • Targeting TGFβ signal transduction for cancer therapy, 2021, Signal Transduction and Targeted Therapy
  • Cancer associated-fibroblast-derived exosomes in cancer progression, 2021, Molecular Cancer
  • TGF-β-Induced Endothelial to Mesenchymal Transition in Disease and Tissue Engineering, 2020, Frontiers in Cell and Developmental Biology
  • On-Target Anti-TGF-β Therapies Are Not Succeeding in Clinical Cancer Treatments: What Are Remaining Challenges?, 2020, Frontiers in Cell and Developmental Biology

Frequent co-authors collaborating with Peter ten Dijke include:

  • Maarten van Dinther
  • Gonzalo Sánchez-Duffhues
  • Pouyan E. Boukany
  • Marie-José Goumans
  • Hailiang Mei

The scientist's work has been published in a variety of venues, with several journals featuring multiple papers:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Cell and Developmental Biology
  • Nature Communications
  • Journal of Visualized Experiments
  • Signal Transduction and Targeted Therapy

An award held by Peter ten Dijke is membership in the European Molecular Biology Organization (EMBO).

Best Publications

  • TGF-beta signalling from cell membrane to nucleus through SMAD proteins

    Carl-Henrik Heldin;Kohei Miyazono;Peter ten Dijke

  • Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways

    Hidenori Ichijo;Eisuke Nishida;Kenji Irie;Peter ten Dijke

  • Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling

    Atsuhito Nakao;Mozhgan Afrakhte;Anita Morn;Takuya Nakayama

  • New insights into TGF-beta-Smad signalling.

    Peter ten Dijke;Caroline S Hill

  • Balancing the activation state of the endothelium via two distinct TGF‐β type I receptors

    Marie‐José Goumans;Gudrun Valdimarsdottir;Susumu Itoh;Alexander Rosendahl

  • TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4.

    Atsuhito Nakao;Takeshi Imamura;Takeshi Imamura;Serhiy Souchelnytskyi;Masahiro Kawabata

  • Specificity, diversity, and regulation in TGF-β superfamily signaling

    Ester Piek;Carl-Henrik Heldin;Peter Ten Dijke

  • Activin receptor-like kinase 1 modulates transforming growth factor-β1 signaling in the regulation of angiogenesis

    S. Paul Oh;Tsugio Seki;Kendrick A. Goss;Takeshi Imamura

  • Sclerostin Is an Osteocyte-expressed Negative Regulator of Bone Formation, But Not a Classical BMP Antagonist

    Rutger L. van Bezooijen;Bernard A.J. Roelen;Annemieke Visser;Lianne van der Wee-Pals

  • Identification and Functional Characterization of Distinct Critically Important Bone Morphogenetic Protein-specific Response Elements in the Id1 Promoter

    Olexander Korchynskyi;Peter ten Dijke

  • Transforming Growth Factor-β1 to the Bone

    Katrien Janssens;Peter ten Dijke;Sophie Janssens;Wim Van Hul

  • TGF-β-Mediated Epithelial-Mesenchymal Transition and Cancer Metastasis

    Yang Hao;David Baker;Peter ten Dijke

  • Activin Receptor-like Kinase (ALK)1 Is an Antagonistic Mediator of Lateral TGFβ/ALK5 Signaling

    Marie José Goumans;Gudrun Valdimarsdottir;Susumu Itoh;Franck Lebrin

  • Targeting TGF-β Signaling in Cancer.

    Selcuk Colak;Peter ten Dijke;Peter ten Dijke;Peter ten Dijke

  • Signaling of transforming growth factor-β family members through Smad proteins

    Susumu Itoh;Fumiko Itoh;Marie‐José Goumans;Peter ten Dijke

  • TGF-β in progression of liver disease

    Steven Dooley;Peter ten Dijke

  • Endoglin promotes endothelial cell proliferation and TGF‐β/ALK1 signal transduction

    Franck Lebrin;Marie-José Goumans;Marie-José Goumans;Leon Jonker;Rita L C Carvalho

  • Apoptosis in podocytes induced by TGF-β and Smad7

    Mario Schiffer;Markus Bitzer;Ian S.D. Roberts;Jeffrey B. Kopp

  • TGF-beta signaling in vascular biology and dysfunction.

    Marie-José Goumans;Zhen Liu;Peter ten Dijke

  • Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice.

    Jonas Larsson;Marie-José Goumans;Lottie Jansson Sjöstrand;Marga A. van Rooijen

Frequent Co-Authors

Marie-José Goumans
Marie-José Goumans Leiden University Medical Center
Carl-Henrik Heldin
Carl-Henrik Heldin Uppsala University
Kohei Miyazono
Kohei Miyazono University of Tokyo
Chandra S. Verma
Chandra S. Verma Agency for Science, Technology and Research
Clemens W.G.M. Löwik
Clemens W.G.M. Löwik Erasmus University Rotterdam
Takeshi Imamura
Takeshi Imamura Ehime University
Susumu Itoh
Susumu Itoh Showa Pharmaceutical University
Christine L. Mummery
Christine L. Mummery Leiden University Medical Center
Isabel Fabregat
Isabel Fabregat University of Barcelona
David Baker
David Baker University of Washington

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