D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 113 Citations 57,731 171 World Ranking 246 National Ranking 149

Research.com Recognitions

Awards & Achievements

2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Genetics

The scientist’s investigation covers issues in Cell biology, Transforming growth factor beta, Transforming growth factor, Molecular biology and Internal medicine. Rik Derynck is studying Signal transduction, which is a component of Cell biology. His Transforming growth factor beta study combines topics from a wide range of disciplines, such as TGF beta signaling pathway, Cancer research and Immunology.

His Transforming growth factor research includes elements of Cell culture, Autocrine signalling, Biochemistry, Growth factor and Transforming growth factor, beta 3. Rik Derynck has researched Molecular biology in several fields, including Biosynthesis, Psychological repression, Transcription, Interferon gamma and Complementary DNA. His Internal medicine research includes themes of Endocrinology and Cartilage.

His most cited work include:

  • Smad-dependent and Smad-independent pathways in TGF-β family signalling (4014 citations)
  • Molecular mechanisms of epithelial–mesenchymal transition (3857 citations)
  • TGF-beta signaling in tumor suppression and cancer progression. (1950 citations)

What are the main themes of his work throughout his whole career to date?

Rik Derynck mainly investigates Cell biology, Molecular biology, Transforming growth factor, Transforming growth factor beta and Signal transduction. His Cell biology study incorporates themes from Receptor, Internal medicine, Endocrinology and Cellular differentiation. His studies deal with areas such as Transcription factor, Complementary DNA, Peptide sequence, Messenger RNA and Gene as well as Molecular biology.

His Transforming growth factor research is multidisciplinary, relying on both Cell culture, Autocrine signalling, Cancer research and Growth factor, TGF alpha. Rik Derynck studied Transforming growth factor beta and Mesenchymal stem cell that intersect with Bone morphogenetic protein. His work investigates the relationship between Signal transduction and topics such as Epithelial–mesenchymal transition that intersect with problems in Reprogramming and Transdifferentiation.

He most often published in these fields:

  • Cell biology (45.21%)
  • Molecular biology (32.57%)
  • Transforming growth factor (31.80%)

What were the highlights of his more recent work (between 2007-2021)?

  • Cell biology (45.21%)
  • Signal transduction (17.62%)
  • Transforming growth factor (31.80%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Cell biology, Signal transduction, Transforming growth factor, Cancer research and Epithelial–mesenchymal transition. The concepts of his Cell biology study are interwoven with issues in Receptor and Cellular differentiation. The study incorporates disciplines such as Cancer and Bone morphogenetic protein in addition to Signal transduction.

His Transforming growth factor study also includes fields such as

  • Cell growth that connect with fields like MAPK/ERK pathway,
  • Extracellular matrix that connect with fields like RUNX2. Rik Derynck has included themes like Reprogramming, Transdifferentiation, Immunology, Lung metastasis and Mesenchymal stem cell in his Epithelial–mesenchymal transition study. To a larger extent, he studies Endocrinology with the aim of understanding Transforming growth factor beta.

Between 2007 and 2021, his most popular works were:

  • Molecular mechanisms of epithelial–mesenchymal transition (3857 citations)
  • TGF-beta-induced epithelial to mesenchymal transition. (1607 citations)
  • TGF-β signaling and epithelial-mesenchymal transition in cancer progression. (501 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Genetics

Rik Derynck mostly deals with Cell biology, Signal transduction, Epithelial–mesenchymal transition, SMAD and Transforming growth factor beta. He mostly deals with Transforming growth factor in his studies of Cell biology. As part of the same scientific family, Rik Derynck usually focuses on Transforming growth factor, concentrating on Kinase and intersecting with Molecular biology.

Within one scientific family, Rik Derynck focuses on topics pertaining to Cancer under Signal transduction, and may sometimes address concerns connected to microRNA, Motility, Tgf β signaling and Transition. He interconnects Transdifferentiation, Stem cell, Reprogramming and Mesenchymal stem cell in the investigation of issues within Epithelial–mesenchymal transition. His biological study spans a wide range of topics, including Cancer research, Stromal cell and Bone morphogenetic protein.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Smad-dependent and Smad-independent pathways in TGF-β family signalling

Rik Derynck;Ying E. Zhang.
Nature (2003)

6682 Citations

Molecular mechanisms of epithelial–mesenchymal transition

Samy Lamouille;Jian Xu;Rik Derynck.
Nature Reviews Molecular Cell Biology (2014)

5405 Citations

TGF-beta signaling in tumor suppression and cancer progression.

Rik Derynck;Rosemary J. Akhurst;Allan Balmain.
Nature Genetics (2001)

3319 Citations

TGF-beta-induced epithelial to mesenchymal transition.

Jian Xu;Samy Lamouille;Rik Derynck.
Cell Research (2009)

2587 Citations

Human transforming growth factor-beta complementary DNA sequence and expression in normal and transformed cells.

Rik Derynck;Julie A. Jarrett;Ellson Y. Chen;Dennis H. Eaton.
Nature (1985)

2397 Citations

Human tumour necrosis factor: Precursor structure, expression and homology to lymphotoxin

Diane Pennica;Glenn E. Nedwin;Joel S. Hayflick;Peter H. Seeburg.
Nature (1984)

2297 Citations

SPECIFICITY AND VERSATILITY IN TGF-β SIGNALING THROUGH SMADS

Xin-Hua Feng;Rik Derynck.
Annual Review of Cell and Developmental Biology (2005)

2140 Citations

Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth.

John H. Kehrl;Lalage M. Wakefield;Anita B. Roberts;Sonia Jakowlew.
Journal of Experimental Medicine (1986)

1982 Citations

Evidence that transforming growth factor-β is a hormonally regulated negative growth factor in human breast cancer cells

Cornelius Knabbe;Marc E. Lippman;Lalage M. Wakefield;Kathleen C. Flanders.
Cell (1987)

1456 Citations

Transforming growth factor α

Rik Derynck.
Cell (1988)

1322 Citations

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