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Molecular Biology
USA
2026

D-Index & Metrics

Molecular Biology

D-Index
150
Citations
100938
World Ranking
84
National Ranking
52

Research.com Recognitions

  • 2026 - Research.com Molecular Biology in United States Leader Award
  • 2025 - Research.com Molecular Biology in United States Leader Award
  • 2023 - Research.com Molecular Biology in United States Leader Award
  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Rik Derynck is affiliated with the University of California, San Francisco in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a focus on Molecular Biology, Pulmonary and Respiratory Medicine, Biophysics, Oncology, and Pathology and Forensic Medicine.

The scientist's main research topics include:

  • Cancer Cells and Metastasis
  • TGF-β signaling in diseases
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Cell Image Analysis Techniques
  • Viral Infectious Diseases and Gene Expression in Insects
  • Advanced Fluorescence Microscopy Techniques
  • Genetic factors in colorectal cancer

Recent notable publications authored or co-authored by Rik Derynck include:

  • "Guidelines and definitions for research on epithelial-mesenchymal transition," 2020, Nature Reviews Molecular Cell Biology
  • "TGFβ biology in cancer progression and immunotherapy," 2020, Nature Reviews Clinical Oncology
  • "TGF-β as a driver of fibrosis: physiological roles and therapeutic opportunities," 2021, The Journal of Pathology
  • "Epithelial plasticity, epithelial-mesenchymal transition, and the TGF-β family," 2021, Developmental Cell
  • "Virtual screening for small-molecule pathway regulators by image-profile matching," 2022, Cell Systems

Frequent co-authors collaborating with Rik Derynck include:

  • Jing Yang
  • Parker B. Antin
  • Geert Berx
  • Cédric Blanpain
  • Thomas Brabletz

The scientist has published multiple papers in prominent venues, including:

  • Nature Reviews Molecular Cell Biology
  • Nature Reviews Clinical Oncology
  • The Journal of Pathology
  • Developmental Cell
  • Cell Systems

Rik Derynck was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2010.

Best Publications

  • Molecular mechanisms of epithelial–mesenchymal transition

    Samy Lamouille;Jian Xu;Rik Derynck

  • Smad-dependent and Smad-independent pathways in TGF-beta family signalling.

    Rik Derynck;Ying E. Zhang

  • TGF-beta-induced epithelial to mesenchymal transition.

    Jian Xu;Samy Lamouille;Rik Derynck

  • TGF-beta signaling in tumor suppression and cancer progression.

    Rik Derynck;Rosemary J. Akhurst;Allan Balmain

  • Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin.

    Diane Pennica;Glenn E. Nedwin;Joel S. Hayflick;Peter H. Seeburg

  • SPECIFICITY AND VERSATILITY IN TGF-β SIGNALING THROUGH SMADS

    Xin-Hua Feng;Rik Derynck

  • Human transforming growth factor-beta complementary DNA sequence and expression in normal and transformed cells.

    Rik Derynck;Julie A. Jarrett;Ellson Y. Chen;Dennis H. Eaton

  • Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth.

    John H. Kehrl;Lalage M. Wakefield;Anita B. Roberts;Sonia Jakowlew

  • Smads: transcriptional activators of TGF-beta responses.

    Rik Derynck;Ying Zhang;Xin-Hua Feng

  • Guidelines and definitions for research on epithelial–mesenchymal transition

    Jing Yang;Parker Antin;Geert Berx;Cédric Blanpain

  • Evidence that transforming growth factor-β is a hormonally regulated negative growth factor in human breast cancer cells

    Cornelius Knabbe;Marc E. Lippman;Lalage M. Wakefield;Kathleen C. Flanders

  • Transforming growth factor α

    Rik Derynck

  • Synthesis of Messenger RNAs for Transforming Growth Factors α and β and the Epidermal Growth Factor Receptor by Human Tumors

    Rik Derynck;David V. Goeddel;Axel Ullrich;Jordan U. Gutterman

  • Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor

    Päivi J. Miettinen;Joel E. Berger;Juanito Meneses;Yume Phung

  • Human transforming growth factor-α: Precursor structure and expression in E. coli

    Rik Derynck;Anita B. Roberts;Marjorie E. Winkler;Ellson Y. Chen

  • TGF-β and the TGF-β Family: Context-Dependent Roles in Cell and Tissue Physiology

    Masato Morikawa;Rik Derynck;Kohei Miyazono

  • Transforming growth factor-alpha: a more potent angiogenic mediator than epidermal growth factor

    Alain B. Schreiber;Marjorie E. Winkler;Rik Derynck

  • TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors.

    P J Miettinen;R Ebner;A R Lopez;R Derynck

  • Receptor-associated Mad homologues synergize as effectors of the TGF-β response

    Ying Zhang;Xin-Hua Feng;Rui-Yun Wu;Rik Derynck

  • Transforming growth factor-alpha.

    Rik Derynck

Frequent Co-Authors

David V. Goeddel
David V. Goeddel The Colum Group
Xin-Hua Feng
Xin-Hua Feng Zhejiang University
Rosemary J. Akhurst
Rosemary J. Akhurst University of California, San Francisco
Walter Fiers
Walter Fiers Ghent University
Harold L. Moses
Harold L. Moses Vanderbilt University
Reinhard Ebner
Reinhard Ebner Human Genome Sciences (United States)
Anita B. Roberts
Anita B. Roberts National Institutes of Health
Ruey-Hwa Chen
Ruey-Hwa Chen Academia Sinica
Zena Werb
Zena Werb University of California, San Francisco
Robert J. Coffey
Robert J. Coffey Vanderbilt University Medical Center

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