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D-Index
130
Citations
76828
World Ranking
2456
National Ranking
1389

Overview

Robert J. Coffey is affiliated with Vanderbilt University Medical Center in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a particular concentration on oncology and cancer research.

Their subfields of study include molecular biology, cancer research, oncology, biophysics, and pulmonary and respiratory medicine. The main topics investigated by Coffey encompass:

  • Extracellular vesicles in disease
  • MicroRNA in disease regulation
  • Single-cell and spatial transcriptomics
  • Cancer cells and metastasis
  • Genetic factors in colorectal cancer
  • Colorectal cancer treatments and studies
  • Cell image analysis techniques

Among recent publications attributed to the researcher are:

  • "The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution", 2020, Cell
  • "Extracellular vesicles and nanoparticles: emerging complexities", 2023, Trends in Cell Biology
  • "Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets", 2021, Nature Cell Biology
  • "Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps", 2021, Cell
  • "Comprehensive isolation of extracellular vesicles and nanoparticles", 2023, Nature Protocols

Frequent coauthors in Coffey's body of work include Ken S. Lau, Jeffrey L. Franklin, Martha J. Shrubsole, James N. Higginbotham, and Nicholas O. Markham.

The researcher's publications are often featured in these venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Gastroenterology
  • Communications Biology
  • Cell

Robert J. Coffey's publications reflect extensive engagement in fields related to molecular biology and oncology, with concentrated interests in extracellular vesicles and cancer-related studies. Their work contributes to understanding disease mechanisms at high resolution, including the dynamics of tumor development and cellular communications mediated by extracellular nanoparticles.

Best Publications

  • Minimal information for studies of extracellular vesicles 2018 (MISEV2018) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

    Clotilde Théry;Kenneth W. Witwer;Elena Aikawa;Maria Jose Alcaraz

  • Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

    Charles E. Eberhart;Robert J. Coffey;Aramandla Radhika;Francis M. Giardiello

  • Reassessment of Exosome Composition

    Dennis K. Jeppesen;Aidan M. Fenix;Jeffrey L. Franklin;James N. Higginbotham

  • Targeted Disruption of Mouse EGF Receptor: Effect of Genetic Background on Mutant Phenotype

    David W. Threadgill;Andrzej A. Dlugosz;Laura A. Hansen;Tamar Tennenbaum

  • Proteogenomic characterization of human colon and rectal cancer

    Bing Zhang;Jing Wang;Xiaojing Wang;Jing Zhu

  • Randomized controlled trial of intraputamenal glial cell line-derived neurotrophic factor infusion in Parkinson disease.

    Anthony E. Lang;Steven Gill;Nik K. Patel;Andres Lozano

  • EGF receptor ligands

    Raymond C Harris;Eunkyung Chung;Robert J Coffey

  • Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2.

    H Sheng;J Shao;S C Kirkland;P Isakson

  • Stereotactic radiosurgery for arteriovenous malformations of the brain.

    L D Lunsford;D Kondziolka;J C Flickinger;D J Bissonette

  • A multi-institutional experience with stereotactic radiosurgery for solitary brain metastasis

    John C Flickinger;Douglas Kondziolka;L Dade Lunsford;Robert J Coffey

  • The Pan-ErbB Negative Regulator Lrig1 Is an Intestinal Stem Cell Marker that Functions as a Tumor Suppressor

    Anne E. Powell;Yang Wang;Yina Li;Emily J. Poulin

  • Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer

    J. Joshua Smith;Natasha G. Deane;Fei Wu;Nipun B. Merchant

  • Pathology of mouse models of intestinal cancer: Consensus report and recommendations

    Gregory P. Boivin;Kay Washington;Kan Yang;Jerrold M. Ward

  • Synergistic interaction between hypergastrinemia and Helicobacter infection in a mouse model of gastric cancer.

    Timothy C. Wang;Charles A. Dangler;Duan Chen;James R. Goldenring

  • Overexpression of transforming growth factor α in psoriatic epidermis

    James T. Elder;Gary J. Fisher;Patricia B. Lindquist;Gregory L. Bennett

  • Type beta transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat

    William E. Russell;Robert J. Coffey;Andre J. Ouellette;Harold L. Moses

  • Proteomic Analysis of Exosomes from Mutant KRAS Colon Cancer Cells Identifies Intercellular Transfer of Mutant KRAS

    Michelle Demory Beckler;James N. Higginbotham;Jeffrey L. Franklin;Jeffrey L. Franklin;Amy-Joan Ham

  • Development of mammary hyperplasia and neoplasia in MMTV-TGFα transgenic mice

    Yasuhisa Matsui;Susan A. Halter;Jeffrey T. Holt;Brigid L.M. Hogan

  • Suramin inhibition of growth factor receptor binding and mitogenicity in AKR‐2B cells

    Robert J. Coffey;Edward B. Leof;Gary D. Shipley;Harold L. Moses

  • A new type of transforming growth factor-beta, TGF-beta 3.

    R Derynck;P B Lindquist;A Lee;D Wen

Frequent Co-Authors

James R. Goldenring
James R. Goldenring Vanderbilt University
Peter J. Dempsey
Peter J. Dempsey University of Colorado Denver
John C. Flickinger
John C. Flickinger University of Pittsburgh
Harold L. Moses
Harold L. Moses Vanderbilt University
L. Dade Lunsford
L. Dade Lunsford University of Pittsburgh
Bing Zhang
Bing Zhang Baylor College of Medicine
Jason D. Morrow
Jason D. Morrow Vanderbilt University
David W. Threadgill
David W. Threadgill Texas A&M University
Shawn Levy
Shawn Levy Vanderbilt University

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