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Biology and Biochemistry

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71
Citations
14808
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6788
National Ranking
515

Overview

Martin J. Donnelly is affiliated with the Liverpool School of Tropical Medicine in the United Kingdom. Their research primarily focuses on medicine, with particular emphasis on public health, environmental and occupational health, molecular biology, plant science, parasitology, and infectious diseases.

The main topics of Donnelly's work include:

  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • Insect Resistance and Genetics
  • Insect Pest Control Strategies
  • Parasites and Host Interactions
  • Viral Infections and Vectors
  • Insect symbiosis and bacterial influences

Their recent publications highlight a range of studies on malaria vectors and insecticide resistance. Selected papers include:

  • "Effect of long-lasting insecticidal nets with and without piperonyl butoxide on malaria indicators in Uganda (LLINEUP): a pragmatic, cluster-randomised trial embedded in a national LLIN distribution campaign," published in The Lancet (2020)
  • "Genome variation and population structure among 1142 mosquitoes of the African malaria vector species Anopheles gambiae and Anopheles coluzzii," published in Genome Research (2020)
  • "The genetic architecture of target-site resistance to pyrethroid insecticides in the African malaria vectors Anopheles gambiae and Anopheles coluzzii," published in Molecular Ecology (2021)
  • "Impact of indoor residual spraying with pirimiphos-methyl (Actellic 300CS) on entomological indicators of transmission and malaria case burden in Migori County, western Kenya," published in Scientific Reports (2020)
  • "Genome-wide association studies reveal novel loci associated with pyrethroid and organophosphate resistance in Anopheles gambiae and Anopheles coluzzii," published in Nature Communications (2023)

Donnelly's frequent coauthors include:

  • David Weetman
  • Sarah G. Staedke
  • Eric R. Lucas
  • Alistair Miles
  • Moses R. Kamya

The scientist's work is commonly published in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Malaria Journal
  • Research Square (Research Square)
  • Scientific Reports
  • PLOS Global Public Health

Best Publications

  • Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes

    Daniel E. Neafsey;Robert M. Waterhouse;Mohammad R. Abai;Sergey S. Aganezov

  • Genetic diversity of the African malaria vector Anopheles gambiae.

    Alistair Miles;Alistair Miles;Nicholas J. Harding;Giordano Bottà;Giordano Bottà;Chris S. Clarkson;Chris S. Clarkson

  • A mutation in the voltage-gated sodium channel gene associated with pyrethroid resistance in Latin American Aedes aegypti.

    K. Saavedra-Rodriguez;L. Urdaneta-Marquez;Shavanthi Rajatileka;Shavanthi Rajatileka;M. Moulton

  • The importance of mosquito behavioural adaptations to malaria control in Africa.

    Michelle L. Gatton;Michelle L. Gatton;Nakul Chitnis;Nakul Chitnis;Thomas Churcher;Martin J. Donnelly

  • Field-caught permethrin-resistant Anopheles gambiae overexpress CYP6P3, a P450 that metabolises pyrethroids.

    Pie Müller;Emma Warr;Bradley J. Stevenson;Patricia M. Pignatelli

  • Detection of knockdown resistance (kdr) mutations in Anopheles gambiae: a comparison of two new high-throughput assays with existing methods

    Chris Bass;Dimitra Nikou;Martin J Donnelly;Martin S Williamson

  • Implications of insecticide resistance for malaria vector control with long-lasting insecticidal nets: a WHO-coordinated, prospective, international, observational cohort study

    Immo Kleinschmidt;Immo Kleinschmidt;John Bradley;Tessa Bellamy Knox;Abraham Peter Mnzava

  • CYP6 P450 enzymes and ACE-1 duplication produce extreme and multiple insecticide resistance in the malaria mosquito Anopheles gambiae.

    Constant V. Edi;Luc Djogbénou;Adam M. Jenkins;Kimberly Regna

  • Distribution of knock-down resistance mutations in Anopheles gambiae molecular forms in west and west-central Africa

    Federica Santolamazza;Maria Calzetta;Josiane Etang;Elena Barrese

  • Identification and validation of a gene causing cross-resistance between insecticide classes in Anopheles gambiae from Ghana

    Sara N. Mitchell;Bradley J. Stevenson;Pie Müller;Craig S. Wilding

  • Malaria in Uganda: challenges to control on the long road to elimination: I. Epidemiology and current control efforts.

    Adoke Yeka;Anne Gasasira;Arthur Mpimbaza;Jane Achan

  • Estimating the annual entomological inoculation rate for Plasmodium falciparum transmitted by Anopheles gambiae s.l. using three sampling methods in three sites in Uganda

    Maxwell Kilama;David L Smith;Robert Hutchinson;Ruth Kigozi

  • Windborne long-distance migration of malaria mosquitoes in the Sahel

    Diana L. Huestis;Adama Dao;Moussa Diallo;Zana L. Sanogo

  • Footprints of positive selection associated with a mutation (N1575Y) in the voltage-gated sodium channel of Anopheles gambiae

    Christopher M. Jones;Milindu Liyanapathirana;Fiacre R. Agossa;David Weetman

  • Macrofilaricidal activity of tetracycline against the filarial nematode Onchocerca ochengi: elimination of Wolbachia precedes worm death and suggests a dependent relationship

    N. G. Langworthy;A. Renz;U. Mackenstedt;K. Henkle–Dührsen

  • Impact of urban agriculture on malaria vectors in Accra, Ghana

    Eveline Klinkenberg;Eveline Klinkenberg;PJ McCall;Michael D Wilson;Felix P Amerasinghe

  • Does kdr genotype predict insecticide-resistance phenotype in mosquitoes?

    Martin J. Donnelly;Vincent Corbel;David Weetman;Craig S. Wilding

  • Malaria and urbanization in sub-Saharan Africa

    Martin J Donnelly;PJ McCall;Christian Lengeler;Imelda Bates

  • Adaptive introgression between Anopheles sibling species eliminates a major genomic island but not reproductive isolation.

    Christopher S. Clarkson;David Weetman;John Essandoh;Alexander E. Yawson

  • Evidence for Recent Population Expansion in the Evolutionary History of the Malaria Vectors Anopheles arabiensis and Anopheles gambiae

    Martin J. Donnelly;Monica C. Licht;Tovi Lehmann

Frequent Co-Authors

Dominic P. Kwiatkowski
Dominic P. Kwiatkowski University of Oxford
Hilary Ranson
Hilary Ranson Liverpool School of Tropical Medicine
Janet Hemingway
Janet Hemingway Liverpool School of Tropical Medicine
Sarah G. Staedke
Sarah G. Staedke Liverpool School of Tropical Medicine
Frédéric Simard
Frédéric Simard University of Montpellier
Grant Dorsey
Grant Dorsey University of California, San Francisco
Moses R. Kamya
Moses R. Kamya Makerere University
Charles M. Mbogo
Charles M. Mbogo Wellcome Trust
Alessandra della Torre
Alessandra della Torre Sapienza University of Rome
John S. Bradley
John S. Bradley University of California, San Diego

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