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Biology and Biochemistry

D-Index
68
Citations
15740
World Ranking
7830
National Ranking
3560

Overview

Peter J. Dempsey is affiliated with the University of Colorado Denver in the United States and has contributed to research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work covers several subfields including Oncology, Cell Biology, Molecular Biology, Biomedical Engineering, and Biotechnology.

Dempsey's research topics focus on areas such as Cancer Cells and Metastasis, Cellular Mechanics and Interactions, 3D Printing in Biomedical Research, Hippo pathway signaling and YAP/TAZ, Cancer Research and Treatments, Liver physiology and pathology, and FOXO transcription factor regulation.

Recent publications by Dempsey include:

  • Relaxation of Extracellular Matrix Forces Directs Crypt Formation and Architecture in Intestinal Organoids (2020) in Advanced Healthcare Materials
  • The Effect of Thiol Structure on Allyl Sulfide Photodegradable Hydrogels and their Application as a Degradable Scaffold for Organoid Passaging (2020) in Advanced Materials
  • In situ modulation of intestinal organoid epithelial curvature through photoinduced viscoelasticity directs crypt morphogenesis (2023) in Science Advances
  • Injury-Induced Cellular Plasticity Drives Intestinal Regeneration (2021) in Cellular and Molecular Gastroenterology and Hepatology
  • In Situ Super-Resolution Imaging of Organoids and Extracellular Matrix Interactions via Phototransfer by Allyl Sulfide Exchange-Expansion Microscopy (PhASE-ExM) (2022) in Advanced Materials

Frequent coauthors of Dempsey include:

  • Kristi S. Anseth
  • F. Max Yavitt
  • Michael R. Blatchley
  • Ella A. Hushka
  • Bruce E. Kirkpatrick

Dempsey's research has been published often in venues such as Advanced Materials, Advanced Healthcare Materials, Cellular and Molecular Gastroenterology and Hepatology, Gastroenterology, and Science Advances.

Best Publications

  • Pharmacogenomic Predictor of Sensitivity to Preoperative Chemotherapy With Paclitaxel and Fluorouracil, Doxorubicin, and Cyclophosphamide in Breast Cancer

    Kenneth R. Hess;Keith Anderson;W. Fraser Symmans;Vicente Valero

  • Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1).

    Kyle J. Garton;Peter J. Gough;Carl P. Blobel;Gillian Murphy

  • Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.

    R. B. Kim;C. Wandel;B. Leake;M. Cvetkovic

  • Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells

    Kelli L. VanDussen;Alexis J. Carulli;Theresa M. Keeley;Sanjeevkumar R. Patel

  • Breast cancer screening and diagnosis: Clinical practice guidelines in oncology™

    Therese B. Bevers;Benjamin O. Anderson;Ermelinda Bonaccio;Patrick I. Borgen

  • ADAMs as mediators of EGF receptor transactivation by G protein-coupled receptors.

    Haruhiko Ohtsu;Peter J. Dempsey;Satoru Eguchi

  • Epidermal growth factor receptor activation induces nuclear targeting of cyclooxygenase-2, basolateral release of prostaglandins, and mitogenesis in polarizing colon cancer cells

    Robert J. Coffey;Chris J. Hawkey;Chris J. Hawkey;Lars Damstrup;Lars Damstrup;Ramona Graves-Deal;Ramona Graves-Deal

  • Breast Cancer Screening and Diagnosis

    Therese B. Bevers;Benjamin O. Anderson;Ermelinda Bonaccio;Sandra Buys

  • Activation of MAPKs by angiotensin II in vascular smooth muscle cells. Metalloprotease-dependent EGF receptor activation is required for activation of ERK and p38 MAPK but not for JNK.

    Satoru Eguchi;Peter J. Dempsey;Peter J. Dempsey;Gerald D. Frank;Evangeline D. Motley

  • Conditional gene targeting in mouse pancreatic β-cells: Analysis of ectopic Cre transgene expression in the brain

    Barton Wicksteed;Marcela Brissova;Wenbo Yan;Darren M. Opland

  • Stimulated Shedding of Vascular Cell Adhesion Molecule 1 (VCAM-1) Is Mediated by Tumor Necrosis Factor-α-converting Enzyme (ADAM 17)

    Kyle J. Garton;Peter J. Gough;Julie Philalay;Paul T. Wille

  • TRP Channel Regulates EGFR Signaling in Hair Morphogenesis and Skin Barrier Formation

    Xiping Cheng;Jie Jin;Lily Hu;Dongbiao Shen

  • Metalloprotease-mediated ligand release regulates autocrine signaling through the epidermal growth factor receptor.

    Jianying Dong;L. K. Opresko;P. J. Dempsey;D. A. Lauffenburger

  • A disintegrin and metalloproteinase 10-mediated cleavage and shedding regulates the cell surface expression of CXC chemokine ligand 16

    Peter J. Gough;Kyle J. Garton;Paul T. Wille;Marcin Rychlewski

  • Metalloproteases regulate T-cell proliferation and effector function via LAG-3

    Nianyu Li;Yao Wang;Karen Forbes;Kate M Vignali

  • Distinct TCR signaling pathways drive proliferation and cytokine production in T cells

    Clifford S. Guy;Kate M. Vignali;Jamshid Temirov;Matthew L. Bettini

  • Transcriptome-wide Analysis Reveals Hallmarks of Human Intestine Development and Maturation In Vitro and In Vivo

    Stacy R. Finkbeiner;David R. Hill;Christopher H. Altheim;Priya H. Dedhia

  • Possible role of transforming growth factor α in the pathogenesis of Ménétrier's disease: Supportive evidence from humans and transgenic mice

    Peter J. Dempsey;James R. Goldenring;Carol J. Soroka;Irvin M. Modlin

  • Identification of rCop-1, a New Member of the CCN Protein Family, as a Negative Regulator for Cell Transformation

    Rong Zhang;Lidia Averboukh;Weimin Zhu;Hong Zhang

  • Sonographic evaluation of infiltrating lobular carcinoma.

    R S Butler;L A Venta;E L Wiley;R L Ellis

Frequent Co-Authors

Robert J. Coffey
Robert J. Coffey Vanderbilt University Medical Center
Daniel H. Teitelbaum
Daniel H. Teitelbaum University of Michigan–Ann Arbor
Howard C. Crawford
Howard C. Crawford University of Michigan–Ann Arbor
Linda C. Samuelson
Linda C. Samuelson University of Michigan–Ann Arbor
Kristi S. Anseth
Kristi S. Anseth University of Colorado Boulder
Elaine W. Raines
Elaine W. Raines University of Washington
Tadashi Inagami
Tadashi Inagami Vanderbilt University
Peter J. Gough
Peter J. Gough Inzen Therapeutics
Martin G. Myers
Martin G. Myers University of Toronto
Stuart H. Yuspa
Stuart H. Yuspa National Institutes of Health

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