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Biology and Biochemistry

D-Index
60
Citations
9735
World Ranking
12204
National Ranking
5211

Research.com Recognitions

  • 2019 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Linda C. Samuelson is affiliated with the University of Michigan-Ann Arbor in the United States. Their primary research area is medicine, with a focus on several related subfields including surgery, molecular biology, oncology, pulmonary and respiratory medicine, and pathology and forensic medicine.

The scientist's work covers multiple topics, reflecting a diverse interest within biomedical research. Key research topics include:

  • Cancer Cells and Metastasis
  • Helicobacter pylori-related gastroenterology studies
  • Digestive system and related health
  • Genetic factors in colorectal cancer
  • Hedgehog Signaling Pathway Studies
  • Wnt/β-catenin signaling in development and cancer
  • Liver physiology and pathology

Samuelson has published in a variety of venues, with frequent contributions to journals and periodicals such as:

  • Physiology
  • Cellular and Molecular Gastroenterology and Hepatology
  • Gastroenterology
  • Nature Communications
  • Hepatology

The list of recent publications illustrates the scope of their scientific involvement. Recent papers include:

  • "MiR130b from Schlafen4 + MDSCs stimulates epithelial proliferation and correlates with preneoplastic changes prior to gastric cancer," 2020, Gut
  • "Hepatobiliary Organoids and Their Applications for Studies of Liver Health and Disease: Are We There Yet?", 2021, Hepatology
  • "Insulin-like Growth Factor-1 and mTORC1 Signaling Promote the Intestinal Regenerative Response After Irradiation Injury," 2020, Cellular and Molecular Gastroenterology and Hepatology
  • "Rapid Crypt Cell Remodeling Regenerates the Intestinal Stem Cell Niche after Notch Inhibition," 2020, Stem Cell Reports
  • "Epithelial Regeneration After Doxorubicin Arises Primarily From Early Progeny of Active Intestinal Stem Cells," 2021, Cellular and Molecular Gastroenterology and Hepatology

Collaborative work is a consistent element of Samuelson's career. Frequent coauthors include:

  • Theresa M. Keeley
  • Elise S. Hibdon
  • Kevin McGowan
  • Elizabeth Delgado
  • Nataliya Razumilava

In 2019, Samuelson was recognized as a Fellow of the American Association for the Advancement of Science (AAAS), reflecting a status among researchers acknowledged by this organization.

Best Publications

  • Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells

    Kelli L. VanDussen;Alexis J. Carulli;Theresa M. Keeley;Sanjeevkumar R. Patel

  • Mediation of tubuloglomerular feedback by adenosine: Evidence from mice lacking adenosine 1 receptors

    Daqing Sun;Linda C. Samuelson;Tianxin Yang;Yuning Huang

  • Endogenous retroviral sequences are required for tissue-specific expression of a human salivary amylase gene.

    Chao-Nan Ting;M. P. Rosenberg;C. M. Snow;L. C. Samuelson

  • Targeted disruption of the pituitary glycoprotein hormone alpha-subunit produces hypogonadal and hypothyroid mice.

    Susan K. Kendall;Linda C. Samuelson;Thomas L. Saunders;Ruth I. Wood

  • Vitronectin is not essential for normal mammalian development and fertility.

    Xianxian Zheng;Thomas L. Saunders;Sally A. Camper;Linda C. Samuelson

  • Impaired gastric acid secretion in gastrin-deficient mice

    Lennart Friis-Hansen;Frank Sundler;Ying Li;Patrick J. Gillespie

  • Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice associated with hypertension and low glomerular filtration rate

    Bryan L. Wharram;Meera Goyal;Patrick J. Gillespie;Jocelyn E. Wiggins

  • Blockade of individual Notch ligands and receptors controls graft-versus-host disease

    Ivy T. Tran;Ashley R. Sandy;Alexis J. Carulli;Christen Ebens

  • Retroviral and Pseudogene Insertion Sites Reveal the Lineage of Human Salivary and Pancreatic Amylase Genes from a Single Gene during Primate Evolution

    Linda C. Samuelson;Karin Wiebauer;Claudette M. Snow;Miriam H. Meisler

  • Prospective identification of a multilineage progenitor in murine stomach epithelium.

    Xiaotan T. Qiao;Joshua W. Ziel;Wendy McKimpson;Blair B. Madison

  • Chronic gastritis in the hypochlorhydric gastrin-deficient mouse progresses to adenocarcinoma

    Yana Zavros;Kathryn A Eaton;Weiqun Kang;Sivaprakash Rathinavelu

  • Mouse atonal homolog 1 directs intestinal progenitors to secretory cell rather than absorptive cell fate.

    Kelli L. VanDussen;Linda C. Samuelson

  • Notch receptor regulation of intestinal stem cell homeostasis and crypt regeneration

    Alexis J. Carulli;Theresa M. Keeley;Elise S. Demitrack;Jooho Chung

  • Concerted evolution of human amylase genes.

    D L Gumucio;K Wiebauer;R M Caldwell;L C Samuelson

  • Genetic or chemical hypochlorhydria is associated with inflammation that modulates parietal and G-cell populations in mice

    Yana Zavros;Gabriele Rieder;Amy Ferguson;Linda C. Samuelson

  • Notch regulation of gastrointestinal stem cells.

    Elise S. Demitrack;Linda C. Samuelson

  • Cloning and Chromosomal Localization of a Gene (GPR18) Encoding a Novel Seven Transmembrane Receptor Highly Expressed in Spleen and Testis

    Ira Gantz;Akira Muraoka;Ying Kui Yang;Linda C. Samuelson

  • Overexpression of Rab3D enhances regulated amylase secretion from pancreatic acini of transgenic mice.

    Hirohide Ohnishi;Linda C. Samuelson;David I. Yule;Stephen A. Ernst

  • Gastric tuft cells express DCLK1 and are expanded in hyperplasia

    Milena Saqui-Salces;Theresa M. Keeley;Ann S. Grosse;Xiaotan T. Qiao

  • Targeted disruption of the mouse villin gene does not impair the morphogenesis of microvilli

    Kathleen I. Pinson;Laura Dunbar;Linda C. Samuelson;Deborah L. Gumucio

Frequent Co-Authors

Juanita L. Merchant
Juanita L. Merchant University of Arizona
Deborah L. Gumucio
Deborah L. Gumucio University of Michigan–Ann Arbor
Kathryn A. Eaton
Kathryn A. Eaton University of Michigan–Ann Arbor
Miriam H. Meisler
Miriam H. Meisler University of Michigan–Ann Arbor
Jens F. Rehfeld
Jens F. Rehfeld University of Copenhagen
Peter J. Dempsey
Peter J. Dempsey University of Colorado Denver
Ivan Maillard
Ivan Maillard University of Pennsylvania
Patrick Tso
Patrick Tso University of Cincinnati
Thomas L. Saunders
Thomas L. Saunders University of Michigan–Ann Arbor
Howard C. Crawford
Howard C. Crawford University of Michigan–Ann Arbor

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