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Juanita L. Merchant

Juanita L. Merchant

D-Index & Metrics

Biology and Biochemistry

D-Index
58
Citations
9041
World Ranking
13458
National Ranking
5709

Research.com Recognitions

  • 2017 - Fellow of the American Academy of Arts and Sciences
  • 2008 - Member of the National Academy of Medicine (NAM)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Juanita L. Merchant is affiliated with the University of Arizona in the United States. Their research work is situated primarily within the field of Medicine, with a significant focus on Oncology, Epidemiology, Immunology, Molecular Biology, and Surgery as subfields.

Their scientific output covers a range of topics including:

  • Neuroendocrine Tumor Research Advances
  • Neuroblastoma Research and Treatments
  • Immune cells in cancer
  • Lung Cancer Research Studies
  • Helicobacter pylori-related gastroenterology studies
  • Pancreatic and Hepatic Oncology Research
  • Digestive system and related health

Merchant has contributed to numerous publications, frequently collaborating with coauthors such as Suzann Duan, Travis W. Sawyer, Ricky Sontz, Sulaiman Sheriff, and Jayati Chakrabarti. Their research has been predominantly published in venues including:

  • Gastroenterology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cellular and Molecular Gastroenterology and Hepatology
  • Endocrine Abstracts
  • Cancers

Recent papers authored or coauthored by Merchant include:

  • Genome-wide analysis of 53,400 people with irritable bowel syndrome highlights shared genetic pathways with mood and anxiety disorders, 2021, Nature Genetics
  • The immune microenvironment in gastric adenocarcinoma, 2022, Nature Reviews Gastroenterology & Hepatology
  • Hedgehog transcriptional effector GLI mediates mTOR-Induced PD-L1 expression in gastric cancer organoids, 2021, Cancer Letters
  • Murine- and Human-Derived Autologous Organoid/Immune Cell Co-Cultures as Pre-Clinical Models of Pancreatic Ductal Adenocarcinoma, 2020, Cancers
  • MiR130b from Schlafen4 + MDSCs stimulates epithelial proliferation and correlates with preneoplastic changes prior to gastric cancer, 2020, Gut

Merchant's work largely relates to cancer biology, particularly gastric cancer and pancreatic ductal adenocarcinoma, incorporating aspects of immune microenvironments and molecular signaling pathways.

They have received recognition in the form of memberships and fellowships, including:

  • Fellow of the American Academy of Arts and Sciences, 2017
  • Member of the National Academy of Medicine (NAM), 2008
  • Member of the Association of American Physicians

Best Publications

  • The same pocket in menin binds both MLL and JUND but has opposite effects on transcription

    Jing Huang;Buddha Gurung;Bingbing Wan;Smita Matkar

  • Sp1 phosphorylation by Erk 2 stimulates DNA binding

    Juanita L. Merchant;Ming Du;Andrea Todisco

  • Helicobacter pylori cag-Type IV Secretion System Facilitates Corpus Colonization to Induce Precancerous Conditions in Mongolian Gerbils

    Gabriele Rieder;Juanita L. Merchant;Rainer Haas

  • Paracrine Hedgehog Signaling in Stomach and Intestine: New Roles for Hedgehog in Gastrointestinal Patterning

    Åsa Kolterud;Ann S. Grosse;William J. Zacharias;Katherine D. Walton

  • ZBP-89, a Krüppel-like zinc finger protein, inhibits epidermal growth factor induction of the gastrin promoter.

    Juanita L. Merchant;Gaitry R. Iyer;Brigit R. Taylor;John R. Kitchen

  • Prospective identification of a multilineage progenitor in murine stomach epithelium.

    Xiaotan T. Qiao;Joshua W. Ziel;Wendy McKimpson;Blair B. Madison

  • Chronic gastritis in the hypochlorhydric gastrin-deficient mouse progresses to adenocarcinoma

    Yana Zavros;Kathryn A Eaton;Weiqun Kang;Sivaprakash Rathinavelu

  • Increased Expression of DUOX2 Is an Epithelial Response to Mucosal Dysbiosis Required for Immune Homeostasis in Mouse Intestine.

    Helmut Grasberger;Jun Gao;Hiroko Nagao-Kitamoto;Sho Kitamoto

  • Transcription Factor ZBP-89 Cooperates with Histone Acetyltransferase p300 during Butyrate Activation of p21 waf1 Transcription in Human Cells

    Longchuan Bai;Juanita L. Merchant

  • Genetic or chemical hypochlorhydria is associated with inflammation that modulates parietal and G-cell populations in mice

    Yana Zavros;Gabriele Rieder;Amy Ferguson;Linda C. Samuelson

  • ZBP-89 promotes growth arrest through stabilization of p53.

    Longchuan Bai;Juanita L. Merchant

  • Butyrate increases IL-23 production by stimulated dendritic cells

    Bradford E. Berndt;Min Zhang;Stephanie Y. Owyang;Tyler S. Cole

  • Evidence that Loss of Sonic Hedgehog is an Indicator of Helicobater pylori -induced Atrophic Gastritis Progressing to Gastric Cancer

    Akiko Shiotani;Hiroyasu Iishi;Noriya Uedo;Shingo Ishiguro

  • Underrepresentation of underrepresented minorities in academic medicine: the need to enhance the pipeline and the pipe.

    Juanita L. Merchant;M. Bishr Omary

  • Interleukin-1β Promotes Gastric Atrophy Through Suppression of Sonic Hedgehog

    Meghna Waghray;Yana Zavros;Milena Saqui-Salces;Mohamad El-Zaatari

  • Acinetobacter lwoffii infection and gastritis.

    Sivaprakash Rathinavelu;Yana Zavros;Juanita L. Merchant

  • Gastric tuft cells express DCLK1 and are expanded in hyperplasia

    Milena Saqui-Salces;Theresa M. Keeley;Ann S. Grosse;Xiaotan T. Qiao

  • Epidermal growth factor stimulation of the human gastrin promoter requires Sp1

    Juanita L. Merchant;Akiko Shiotani;Eric R. Mortensen;Dale K. Shumaker

  • A GC-rich element confers epidermal growth factor responsiveness to transcription from the gastrin promoter.

    J L Merchant;B Demediuk;S J Brand

  • Helicobacter pylori-secreted factors inhibit dendritic cell IL-12 secretion: a mechanism of ineffective host defense.

    John Y. Kao;Sivaprakash Rathinavelu;Kathryn A. Eaton;Longchuan Bai

Frequent Co-Authors

Linda C. Samuelson
Linda C. Samuelson University of Michigan–Ann Arbor
Deborah L. Gumucio
Deborah L. Gumucio University of Michigan–Ann Arbor
John Y. Kao
John Y. Kao University of Michigan–Ann Arbor
Kathryn A. Eaton
Kathryn A. Eaton University of Michigan–Ann Arbor
Andrzej A. Dlugosz
Andrzej A. Dlugosz University of Michigan–Ann Arbor
Paul B.S. Lai
Paul B.S. Lai Chinese University of Hong Kong
Gilbert R. Upchurch
Gilbert R. Upchurch University of Florida
Timothy C. Wang
Timothy C. Wang Columbia University
Gary K. Owens
Gary K. Owens University of Virginia
Jeremy F. Reiter
Jeremy F. Reiter University of California, San Francisco

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